Single point incremental forming of polymers

AbstractThe aim of the present paper is to evaluate the possibility of producing low-cost, small-batch, polymer sheet components by means of single point incremental forming (SPIF) at room temperature. During the research work, five different thermoplastic materials were incrementally formed into cones with an increasing wall angle on a conventional CNC milling machine. In designed experiments, significant process parameters were found, and influential material properties were identified. The experimental results confirm that SPIF of commercial polymer sheets at room temperature has potential for the manufacture of complex parts with very high depths

Experimental characterization of frequency dependent squeezed light

We report on the demonstration of broadband squeezed laser beams that show a frequency dependent orientation of the squeezing ellipse. Carrier frequency as well as quadrature angle were stably locked to a reference laser beam at 1064nm. This frequency dependent squeezing was characterized in terms of noise power spectra and contour plots of Wigner functions. The later were measured by quantum state tomography. Our tomograph allowed a stable lock to a local oscillator beam for arbitrary quadrature angles with one degree precision. Frequency dependent orientations of the squeezing ellipse are necessary for squeezed states of light to provide a broadband sensitivity improvement in third generation gravitational wave interferometers. We consider the application of our system to long baseline interferometers such as a future squeezed light upgraded GEO600 detector.Comment: 8 pages, 8 figure

High quality anti-relaxation coating material for alkali atom vapor cells

We present an experimental investigation of alkali atom vapor cells coated with a high quality anti-relaxation coating material based on alkenes. The prepared cells with single compound alkene based coating showed the longest spin relaxation times which have been measured up to now with room temperature vapor cells. Suggestions are made that chemical binding of a cesium atom and an alkene molecule by attack to the C=C bond plays a crucial role in such improvement of anti-relaxation coating quality

Characterization of an outbreak of equine coronavirus infection in adult horses in Switzerland.

INTRODUCTION Outbreaks of equine coronavirus (ECoV) infections have been described in different parts of the world including Europe. The aim of this report was to describe clinical signs, diagnostic work-up and outcome of the first documented outbreak of ECoV in Switzerland in order to raise the awareness for the disease and its various clinical presentations. The outbreak occurred on a farm with 26 horses. Of these, seven horses developed clinical disease ranging from mild signs such as fever and anorexia to severe signs of acute colitis. One horse died due to severe endotoxemia and circulatory shock secondary to severe acute necrotizing enteritis and colitis. Out of the 26 horses, five horses tested positive for ECoV, including two ponies without any clinical signs of infection. The low number of positive cases should nevertheless be interpreted with caution as testing was only performed on one occasion, over a month after the onset of clinical signs in the first suspected case. This report highlights the importance of diagnostic testing and early implementation of biosecurity measures on a farm with an ECoV outbreak. It should furthermore raise the awareness for unspecific and mild clinical signs such as fever and anorexia in affected animals that are potentially able to spread the disease

Germination of phagocytosed E. cuniculi spores does not significantly contribute to parasitophorous vacuole formation in J774 cells

The obligate intracellular microsporidia have developed a unique invasion mechanism to infect their host cells. Spores explosively evert a tube-like structure and extrude the infectious spore content through this organelle into the host cell. Spores from species of the genus Encephalitozoon were also shown to be efficiently internalized by phagocytosis, which led to the hypothesis that spore germination from inside a phagosome might contribute to the infection process. Here, we challenge this hypothesis by quantifying Encephalitozoon cuniculi infection rates of J774 cells that were incubated with the phagocytosis inhibitor cytochalasin D. We demonstrate that the invasion rate in cytochalasin D-treated cells is identical to untreated controls, although phagocytic uptake of E. cuniculi spores was less than 10% of control samples. This study suggests that germination of phagocytosed spores is not a significant infection mode for E. cuniculi

A 43-GHz Survey in the ELAIS N2 Area

We describe a survey in the ELAIS N2 region with the VLA at 43.4 GHz, carried out with 1627 independent snapshot observations in D-configuration and covering about 0.5 square degrees. One certain source is detected, a previously-catalogued flat-spectrum QSO at z=2.2. A few (<5) other sources may be present at about the 3sigma level, as determined from positions of source-like deflections coinciding with blue stellar objects, or with sources from lower-frequency surveys. Independently we show how all the source-like detections identified in the data can be used with a maximum-likelihood technique to constrain the 43-GHz source counts at a level of ~7 mJy. Previous estimates of the counts at 43 GHz, based on lower-frequency counts and spectral measurements, are consistent with these constraints, although the present results are suggestive of somewhat higher surface densities at the 7 mJy level. They do not provide direct evidence of intrusion of a previously unknown source population, although the several candidate sources need examination before such a population can be ruled out.Comment: 13 pages, 11 figures, 1 table; accepted for publication in Mon. Not R. Astr. So