16,338 research outputs found

    Space Station: Leadership for the Future

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    No longer limited to occasional spectaculars, space has become an essential, almost commonplace dimension of national life. Among other things, space is an arena of competition with our allies and adversaries, a place of business, a field of research, and an avenue of cooperation with our allies. The space station will play a critical role in each of these endeavors. Perhaps the most significant feature of the space station, essential to its utility for science, commerce, and technology, is the permanent nature of its crew. The space station will build upon the tradition of employing new capabilities to explore further and question deeper, and by providing a permanent presence, the station should significantly increase the opportunities for conducting research in space. Economic productivity is, in part, a function of technical innovation. A major thrust of the station design effort is devoted to enhancing performance through advanced technology. The space station represents the commitment of the United States to a future in space. Perhaps most importantly, as recovery from the loss of Challenger and its crew continues, the space station symbolizes the national determination to remain undeterred by tragedy and to continue exploring the frontiers of space

    Asymmetric discrimination of non-speech tonal analogues of vowels

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    Published in final edited form as: J Exp Psychol Hum Percept Perform. 2019 February ; 45(2): 285–300. doi:10.1037/xhp0000603.Directional asymmetries reveal a universal bias in vowel perception favoring extreme vocalic articulations, which lead to acoustic vowel signals with dynamic formant trajectories and well-defined spectral prominences due to the convergence of adjacent formants. The present experiments investigated whether this bias reflects speech-specific processes or general properties of spectral processing in the auditory system. Toward this end, we examined whether analogous asymmetries in perception arise with non-speech tonal analogues that approximate some of the dynamic and static spectral characteristics of naturally-produced /u/ vowels executed with more versus less extreme lip gestures. We found a qualitatively similar but weaker directional effect with two-component tones varying in both the dynamic changes and proximity of their spectral energies. In subsequent experiments, we pinned down the phenomenon using tones that varied in one or both of these two acoustic characteristics. We found comparable asymmetries with tones that differed exclusively in their spectral dynamics, and no asymmetries with tones that differed exclusively in their spectral proximity or both spectral features. We interpret these findings as evidence that dynamic spectral changes are a critical cue for eliciting asymmetries in non-speech tone perception, but that the potential contribution of general auditory processes to asymmetries in vowel perception is limited.Accepted manuscrip

    Board of Registration for Professional Engineers and Land Surveyors

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    Board of Registration for Professional Engineers and Land Surveyors

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    Board of Registration for Professional Engineers and Land Surveyors

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    Distributed Queries for Quality Control Checks in Clinical Trials

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    Operational Quality Control (QC) checks are standard practice in clinical trials and ensure ongoing compliance with the study protocol, standard operating procedures (SOPs) and Good Clinical Practice (GCP). We present a method for defining QC checks as distributed queries over case report forms (CRF) and clinical imaging data- sources. Our distributed query system can integrate time-sensitive information in order to populate QC checks that can facilitate discrepancy resolution workflow in clinical trials
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