29,988 research outputs found

    Differentiating U(1)U(1)^\prime supersymmetric models with right sneutrino and neutralino dark matter

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    We perform a detailed analysis of dark matter signals of supersymmetric models containing an extra U(1)U(1)^\prime gauge group. We investigate scenarios in which either the right sneutrino or the lightest neutralino are phenomenologically acceptable dark matter candidates and we explore the parameter spaces of different supersymmetric realisations featuring an extra U(1)U(1)^\prime. We impose consistency with low energy observables, with known mass limits for the superpartners and ZZ^\prime bosons, as well as with Higgs boson signal strengths, and we moreover verify that predictions for the anomalous magnetic moment of the muon agree with the experimental value and require that the dark matter candidate satisfies the observed relic density and direct and indirect dark matter detection constraints. For the case where the sneutrino is the dark matter candidate, we find distinguishing characteristics among different U(1)U(1)^\prime mixing angles. If the neutralino is the lightest supersymmetric particle, its mass is heavier than that of the light sneutrino in scenarios where the latter is a dark matter candidate, the parameter space is less restricted and differentiation between models is more difficult. We finally comment on the possible collider tests of these models.Comment: 21 pages, 11 figures, version accepted by PR

    USL/DBMS NASA/RECON working paper series. Standards

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    The USL/DBMS NASA/RECON Working Paper Series contains a collection of reports representing results of activities being conducted by the Computer Science Department of the University of Southwestern Louisiana pursuant to the specifications of NASA Contract number NASw-3846. The work on this portion of the contract is being performed jointly by the University of Southwestern Louisiana and Southern University. This report contains the full set of standards for the development, formatting, reviewing, and issuance of entries within the USL/DBMS NASA/RECON Working Paper Series

    Loopholes in ZZ^\prime searches at the LHC: exploring supersymmetric and leptophobic scenarios

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    Searching for heavy vector bosons ZZ^\prime, predicted in models inspired by Grand Unification Theories, is among the challenging objectives of the LHC. The ATLAS and CMS collaborations have looked for ZZ^\prime bosons assuming that they can decay only into Standard Model channels, and have set exclusion limits by investigating dilepton, dijet and to a smaller extent top-antitop final states. In this work we explore possible loopholes in these ZZ^\prime searches by studying supersymmetric as well as leptophobic scenarios. We demonstrate the existence of realizations in which the ZZ^\prime boson automatically evades the typical bounds derived from the analyses of the Drell-Yan invariant-mass spectrum. Dileptonic final states can in contrast only originate from supersymmetric ZZ^\prime decays and are thus accompanied by additional effects. This feature is analyzed in the context of judiciously chosen benchmark configurations, for which visible signals could be expected in future LHC data with a 4σ7σ4\sigma-7\sigma significance. Our results should hence motivate an extension of the current ZZ^\prime search program to account for supersymmetric and leptophobic models.Comment: 32 pages, 15 figures. After JHEP revision. Published on 15 February 201

    General specifications for the development of a USL/DBMS NASA/PC R and D distributed workstation

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    The general specifications for the development of a PC-based distributed workstation (PCDWS) for an information storage and retrieval systems environment are defined. This research proposes the development of a PCDWS prototype as part of the University of Southwestern Louisiana Data Base Management System (USL/DBMS) NASA/PC R and D project in the PC-based workstation environment

    Classical Time Crystals

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    We consider the possibility that classical dynamical systems display motion in their lowest energy state, forming a time analogue of crystalline spatial order. Challenges facing that idea are identified and overcome. We display arbitrary orbits of an angular variable as lowest-energy trajectories for nonsingular Lagrangian systems. Dynamics within orbits of broken symmetry provide a natural arena for formation of time crystals. We exhibit models of that kind, including a model with traveling density waves.Comment: 5 pages, 1 figur

    Performance of Cpred/Cobs concentration ratios as a metric reflecting adherence to antidepressant drug therapy

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    Background: Nonadherence is very common among subjects undergoing pharmacotherapy for schizophrenia and depression. This study aimed to evaluate the performance of the ratio of the nonlinear mixed effects pharmacokinetic model predicted concentration to observed drug concentration (ratio of population predicted to observed concentration (Cpred/Cobs) and ratio of individual predicted to observed concentration (Cipred/Cobs) as a measure of erratic drug exposure, driven primarily by variable execution of the dosage regimen and unknown true dosage history. Methods: Modeling and simulation approaches in conjunction with dosage history information from the Medication Event Monitoring System (MEMS, provided by the "Depression: The search for treatment relevant phenotypes" study), was applied to evaluate the consistency of exposure via simulation studies with scenarios representing a long half-life drug (escitalopram). Adherence rates were calculated based on the percentage of the prescribed doses actually taken correctly during the treatment window of interest. The association between Cpred/Cobs, Cipred/Cobs ratio, and adherence rate was evaluated under various assumptions of known dosing history. Results: Simulations for those scenarios representing a known dosing history were generated from historical MEMS data. Simulations of a long half-life drug exhibited a trend for overprediction of concentrations in patients with a low percentage of doses taken and underprediction of concentrations in patients taking more than their prescribed number of doses. Overall, the ratios did not predict adherence well, except when the true adherence rates were extremely high (greater than 100% of prescribed doses) or extremely low (complete nonadherence). In general, the Cipred/Cobs ratio was a better predictor of adherence rate than the Cpred/Cobs ratio. Correct predictions of extreme (high, low) 7-day adherence rates using Cipred/Cobs were 73.8% and 64.0%. Conclusion: This simulation study demonstrated the limitations of the Cpred/obs and Cipred/obs ratios as metrics for actual dosage intake history, and identified that use of MEMS dosing history monitoring combined with sparse pharmacokinetic sampling is a more reliable approach. © 2011 Feng et al
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