Body-rock or lift-off in flow

Conditions are investigated under which a body lying at rest or rocking on a solid horizontal surface can be removed from the surface by hydrodynamic forces or instead continues rocking. The investigation is motivated by recent observations on Martian dust movement as well as other small- and large-scale applications. The nonlinear theory of fluid-body interaction here has unsteady motion of an inviscid fluid interacting with a moving thin body. Various shapes of body are addressed together with a range of initial conditions. The relevant parameter space is found to be subtle as evolution and shape play substantial roles coupled with scaled mass and gravity effects. Lift-off of the body from the surface generally cannot occur without fluid flow but it can occur either immediately or within a finite time once the fluid flow starts up: parameters for this are found and comparisons are made with Martian observations.Comment: 28 pages, 9 figure

The T-box family

Transcription factors of the T-box family are required both for early cell-fate decisions, such as those necessary for formation of the basic vertebrate body plan, and for differentiation and organogenesis. When mutated, T-box genes give dramatic phenotypes in mouse and zebrafish, and they have been implicated both in fundamentals of limb patterning and in a number of human congenital malformations such as Holt-Oram, ulnar-mammary and DiGeorge syndromes, as well as being amplified in a subset of cancers. Genes encoding members of the T-box family have recently been shown to comprise approximately 0.1% of genomes as diverse as those of nematodes and humans and have been identified in a wide variety of animals from ctenophores (comb jellies) to mammals; they are, however, completely absent from genomes from other organisms (such as the model plant Arabidopsis thaliana)

Intraspeaker Comparisons of Acoustic and Articulatory Variability in American English /r/ Productions

The purpose of this report is to test the hypothesis that speakers utilize an acoustic, rather than articulatory, planning space for speech production. It has been well-documented that many speakers of American English use different tongue configurations to produce /r/ in different phonetic contexts. The acoustic planning hypothesis suggests that although the /r/ configuration varies widely in different contexts, the primary acoustic cue for /r/, a dip in the F3 trajectory, will be less variable due to tradeoffs in articulatory variability, or trading relations, that help maintain a relatively constant F3 trajectory across phonetic contexts. Acoustic data and EMMA articulatory data from seven speakers producing /r/ in different phonetic contexts were analyzed. Visual inspection of the EMMA data at the point of F3 minimum revealed that each speaker appeared to use at least two of three trading relation strategies that would be expected to reduce F3 variability. Articulatory covariance measures confirmed that all seven speakers utilized a trading relation between tongue back height and tongue back horizontal position, six speakers utilized a trading relation between tongue tip height and tongue back height, and the speaker who did not use this latter strategy instead utilized a trading relation between tongue tip height and tongue back horizontal position. Estimates of F3 variability with and without the articulatory covariances indicated that F3 would be much higher for all speakers if the articulatory covariances were not utilized. These conclusions were further supported by a comparison of measured F3 variability to F3 variabilities estimated from the pellet data with and without articulatory covariances. In all subjects, the actual F3 variance was significantly lower than the F3 variance estimated without articulatory covariances, further supporting the conclusion that the articulatory trading relations were being used to reduce F3 variability. Together, these results strongly suggest that the neural control mechanisms underlying speech production make elegant use of trading relations between articulators to maintain a relatively invariant acoustic trace for /r/ across phonetic contexts

Intraspeaker Comparisons of Acoustic and Articulatory Variability in American English /r/ Productions

The purpose of this report is to test the hypothesis that speakers utilize an acoustic, rather than articulatory, planning space for speech production. It has been well-documented that many speakers of American English use different tongue configurations to produce /r/ in different phonetic contexts. The acoustic planning hypothesis suggests that although the /r/ configuration varies widely in different contexts, the primary acoustic cue for /r/, a dip in the F3 trajectory, will be less variable due to tradeoffs in articulatory variability, or trading relations, that help maintain a relatively constant F3 trajectory across phonetic contexts. Acoustic data and EMMA articulatory data from seven speakers producing /r/ in different phonetic contexts were analyzed. Visual inspection of the EMMA data at the point of F3 minimum revealed that each speaker appeared to use at least two of three trading relation strategies that would be expected to reduce F3 variability. Articulatory covariance measures confirmed that all seven speakers utilized a trading relation between tongue back height and tongue back horizontal position, six speakers utilized a trading relation between tongue tip height and tongue back height, and the speaker who did not use this latter strategy instead utilized a trading relation between tongue tip height and tongue back horizontal position. Estimates of F3 variability with and without the articulatory covariances indicated that F3 would be much higher for all speakers if the articulatory covariances were not utilized. These conclusions were further supported by a comparison of measured F3 variability to F3 variabilities estimated from the pellet data with and without articulatory covariances. In all subjects, the actual F3 variance was significantly lower than the F3 variance estimated without articulatory covariances, further supporting the conclusion that the articulatory trading relations were being used to reduce F3 variability. Together, these results strongly suggest that the neural control mechanisms underlying speech production make elegant use of trading relations between articulators to maintain a relatively invariant acoustic trace for /r/ across phonetic contexts

An enigmatic group of arctic island caribou and the potential implications for conservation of biodiversity

We investigated the status of caribou classified as Rangifer tarandus pearyi by DNA analyses, with an emphasis on those large-bodied caribou identified as ultra pearyi that were collected in summer 1958 on Prince of Wales Island, south-central Canadian Arctic Archipelago. Our comparative assessment reveals that the ultra pearyi from Prince of Wales Island belong to a group of pearyi and are not hybrids of pearyi x groenlandicus, as we found for the caribou occurring on nearby Banks Island and northwest Victoria Island. The ultra pearyi from Prince of Wales Island cluster with high arctic pearyi and are separated genetically from the caribou populations that we sampled on the low Canadian Arctic Islands and the Canadian mainland. Our findings reveal biodiversity below the level of subspecies or regional designations. These results support the position that to retain the biodiversity present among caribou populations on the Canadian Arctic Islands, conservation efforts should be targeted at the smaller scale level of the geographic population, rather than on a wider regional or subspecific range-wide basis

Formation of a Quasar Host Galaxy through a Wet Merger 1.4 Billion Years after the Big Bang

We present high-resolution Very Large Array imaging of the molecular gas in the host galaxy of the high redshift quasar BRI 1335-0417 (z=4.41). Our CO(2-1) observations have a linear resolution of 0.15" (1.0 kpc) and resolve the molecular gas emission both spatially and in velocity. The molecular gas in BRI 1335-0417 is extended on scales of 5 kpc, and shows a complex structure. At least three distinct components encompassing about two thirds of the total molecular mass of 9.2 x 10^10 M_sun are identified in velocity space, which are embedded in a structure that harbors about one third of the total molecular mass in the system. The brightest CO(2-1) line emission region has a peak brightness temperature of 61+/-9 K within 1 kpc diameter, which is comparable to the kinetic gas temperature as predicted from the CO line excitation. This is also comparable to the gas temperatures found in the central regions of nearby ultra-luminous infrared galaxies, which are however much more compact than 1 kpc. The spatial and velocity structure of the molecular reservoir in BRI 1335-0417 is inconsistent with a simple gravitationally bound disk, but resembles a merging system. Our observations are consistent with a major, gas-rich (`wet') merger that both feeds an accreting supermassive black hole (causing the bright quasar activity), and fuels a massive starburst that builds up the stellar bulge in this galaxy. Our study of this z>4 quasar host galaxy may thus be the most direct observational evidence that `wet' mergers at high redshift are related to AGN activity.Comment: 5 pages, 4 figures, to appear in ApJL (accepted August 27, 2008

What is the prevalence, and what are the clinical correlates, of insulin resistance in young people presenting for mental health care? A cross-sectional study

Objectives: To report the distribution and predictors of insulin resistance (IR) in young people presenting to primary care-based mental health services. Design: Cross-sectional. Setting: Headspace-linked clinics operated by the Brain and Mind Centre of the University of Sydney. Participants: 768 young people (66% female, mean age 19.7±3.5, range 12–30 years). Main outcome measures: IR was estimated using the updated homeostatic model assessment (HOMA2-IR). Height and weight were collected from direct measurement or self-report for body mass index (BMI). Results: For BMI, 20.6% of the cohort were overweight and 10.2% were obese. However,6.9 mmol/L). By contrast, 9.9% had a HOMA2-IR score \u3e2.0 (suggesting development of IR) and 11.7% (n=90) had a score between 1.5 and 2. Further, there was a positive correlation between BMI and HOMA2-IR (r=0.44, p Conclusions: Emerging IR is evident in a significant subgroup of young people presenting to primary care based mental health services. While the major modifiable risk factor is BMI, a large proportion of the variance is not accounted for by other demographic, clinical or treatment factors. Given the early emergence of IR, secondary prevention interventions may need to commence prior to the development of full-threshold or major mood or psychotic disorders