Comparisons of biochemical parameters before and after supervised physical activity (n = 60).

<p>Data are expressed as mean±SD or as median (interquartil range). FGF21 was log-transformed before analysis. NS = not significant. BMI = body mass index; WC = waist circumference; FFAs = free fatty acids.</p>*<p>Bonferroni adjustment for multiple comparisons. Parameters of the repeated measures model of: Glucose: Hotteling's trace = 0.33; F = 3.29; p = 0.034; Insulin: Hotteling's trace = 1.80; F = 18.01; p<0.0001; FGF21: Hotteling's trace = 2.62; F = 22.76; p<0.0001; FFAs: Hotteling's trace = 1.58; F = 13.2; p<0.0001; Leptin: Hotteling's trace = 0.96; F = 10.93; p<0.0001; Epinephrine: Hotteling's trace = 2.29; F = 19.13; p<0.0001; Adiponectin: Hotteling's trace = 0.17; F = 1.98; p = 0.135.</p

Correlation of the log delta FGF21 (final-basal) levels with METs (A), delta epinephrine (B), and delta free fatty acids (C) in 60 women after two weeks of supervised physical activity.

<p>Correlation of the log delta FGF21 (final-basal) levels with METs (A), delta epinephrine (B), and delta free fatty acids (C) in 60 women after two weeks of supervised physical activity.</p

Correlations of the DELTA log FGF21 (final-basal) with the delta and mean values of related parameters associated with physical activity, lipolysis and adrenergic response (n = 60).

<p>FGF21 was log-transformed before analysis. All the correlations were adjusted for BMI. FGF21 = Fibroblast Growth Factor 21 (ng/l); RHR = Rest heart rate; MHR = Maximum heart rate; METs = Metabolic equivalents; FFA = Free fatty acids;</p>*<p>p<0.05;</p>**<p>p<0.01.</p

Flow chart of the study protocol.

<p>Flow chart of the study protocol.</p

Clinical and biochemical parameters of the sample studied before and after two weeks of supervised physical activity (n = 60).

<p>Data are expressed as mean±SD or as median (interquartil range). NS = not significant. SBP = systolic blood pressure; DBP = diastolic blood pressure; BMI = body mass index; WHR = waist-hip-ratio; ALT = alanine aminotransfarase; AST = aspartate aminotransferase; LDL-C = low-density lipoprotein cholesterol; HDL-C = high-density lipoprotein cholesterol; GGT = gamma-glutamyltransferase.</p>*<p>Daily physical activity measured with questionnaire.</p