The multi-path Traveling Salesman Problem with stochastic travel costs

Given a set of nodes, where each pair of nodes is connected by several paths and each path shows a stochastic travel cost with unknown distribution, the multipath Traveling Salesman Problem with stochastic travel costs aims at finding an expected minimum Hamiltonian tour connecting all nodes. Under a mild assumption on the unknown probability distribution a deterministic approximation of the stochastic problem is given. The comparison of such approximation with a Montecarlo simulation shows both the accuracy and the eciency of the deterministic approximation, with a mean percentage gap around 2% and a reduction of the computational times of two orders of magnitude

HEDGE ACCOUNTING WITHIN IAS 39

This work proposes an accounting calculation scheme for hedging swaps based on the requirements listed under International Accounting Statement (IAS) 39. In particular we developed a procedure that assists risk managers in the identification of the hedging efficiency between a group of loans (or bonds) and swaps held in a bank portfolio qualifying for hedge accounting. The proposed scheme aims at associating to any given swap of the bank portfolio, a certain collection of loans (or bonds) whose risk exposures offset each other. The final result is the construction of a number of hedges that are effective according to IAS 39.Accounting; IAS 39; International Accounting System 39; swap; Hedge

The Cagliari Airport impact on Sardinia tourism: a Logit-based analysis

In the field of air transportation management, traditionally, airlines have been the main actors in the process for deciding which new flights open in a given airport, while airports acted only as the managers of the operations. The changes in the market due to the introduction of low cost companies, with consequent reduction of the airports' fares, as well as the increment of the density of regional airports in several European countries are modifying the mutual roles of airlines and airports. The final decision on new flight to be opened, in fact, is nowadays the result of a negotiation between airlines and airports. The airports must prove the sustainability on the new routes and forecast the economic impact on their catchment area. This paper contributes to advance the current state-of-the-art along two axes. From the pure transportation literature point of view, we introduce a Logit model able to predict the passengers flow in an airport when the management introduces a change in the flight schedule. The model is also able to predict the impact of this change on the airports in the surrounding areas. The second contribution is a case study on the tourist market of the Sardinia region, where we show how to use the results of the model to deduce the economic impact of the decisions of the management of the Cagliari airport on its catchment area in terms of tourists and economic growt

H1-conforming finite element cochain complexes and commuting quasi-interpolation operators on cartesian meshes

A finite element cochain complex on Cartesian meshes of any dimension based on the H1-inner product is introduced. It yields H1-conforming finite element spaces with exterior derivatives in H1. We use a tensor product construction to obtain L2-stable projectors into these spaces which commute with the exterior derivative. The finite element complex is generalized to a family of arbitrary order

Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients

BACKGROUND: Rheumatoid arthritis (RA) patients carry a high risk of cardiovascular morbidity and mortality. The excess of cardiovascular disease cannot be entirely explained by traditional risk factors and the immune system contributes to the development of atherosclerosis. Moreover, post-translational modifications such as citrullination and carbamylation have been linked to inflammation and atherosclerosis. Anti-carbamylated proteins antibodies (anti-CarP) are a new subset of autoantibodies identified in RA patients. This study aimed to investigate a possible association between anti-CarP and subclinical atherosclerosis in RA patients. METHODS: We enrolled RA patients and normal healthy controls (NHS) without known cardiovascular risk factors or heart disease. Cardiovascular risk was assessed using the Modified Systemic Coronary Risk Evaluation (mSCORE). Anti-CarP were investigated by a solid phase "home-made" ELISA. Anti-citrullinated protein antibodies (ACPA) and Rheumatoid Factor (RF) were investigated by ELISA assays. Subclinical atherosclerosis was evaluated by brachial artery Flow-Mediated Dilatation (FMD) and Carotid Intima-Media Thickness (c-IMT) while arterial stiffness by Ankle-Brachial Index (ABI) and Cardio-Ankle Vascular Index (CAVI). RESULTS: We enrolled 50 RA patients (34 F and 16 M, mean age 58.4 ± 13.1 years, mean disease duration 127 ± 96.7 months) and 30 age and sex matched NHS. According to the mSCORE, 58% of patients had a low risk, 32% a moderate and 8% a high risk for cardiovascular disease. FMD was significantly lower in RA patients than in NHS (5.6 ± 3.2 vs 10.7 ± 8.1%; p < 0.004) and CAVIs significantly higher in a RA patients compared to NHS (left CAVI 8.9 ± 1.7 vs 8.1 ± 1.5; p < 0.04 for and right CAVI 8.8 ± 1.6 vs 8.0 ± 1.4; p < 0.04 for the). ABI and c-IMT did not differ between the two populations. The multivariate regression analysis showed a significant association of anti-CarP antibodies with FMD, left and right CAVI and both c-IMT (r = 1.6 and p = 0.05; r = 1.7 and p = 0.04; r = 2.9 and p = 0.05; r = 1.5 and p = 0.03; r = 1.1 and p = 0.03 respectively). CONCLUSIONS: This study confirms that RA patients, without evidence of cardiovascular disease or traditional risk factors, have an impaired endothelial function. Moreover, we found an association with anti-CarP antibodies suggesting a possible contribution of these autoantibodies to endothelial dysfunction, the earliest stage of atherosclerosis. Besides ultrasound assessment, anti-CarP should be assessed in RA patients and considered an additional cardiovascular risk factor

From product performance to consumption experience. The development of a new scale for measuring customer satisfaction

This paper proposes a different approach to customer satisfaction measurement. The nature of the concept is maintained as an evaluation deriving from a comparative process, but we change, or better, extend the terms to which expectations and desires are compared: from product performance alone to the entire consumption experience. The proposed scale has three versions: for convenience, shopping, and specialty goods. The scale for shopping goods was also administered to a sample of buyers of a specific branded product (i.e., a pair of jeans)

Systemic Lupus Erythematosus with and without Anti-dsDNA Antibodies: Analysis from a Large Monocentric Cohort

Objectives. The anti-dsDNA antibodies are a marker for Systemic Lupus Erythematosus (SLE) and 70–98% of patients test positive. We evaluated the demographic, clinical, laboratory, and therapeutical features of a monocentric SLE cohort according to the antidsDNA status. Methods. We identified three groups: anti-dsDNA + (persistent positivity); anti-dsDNA ± (initial positivity and subsequent negativity during disease course); anti-dsDNA − (persistent negativity). Disease activity was assessed by the European Consensus Lupus Activity Measurement (ECLAM). Results. We evaluated 393 patients (anti-dsDNA +: 62.3%; anti-dsDNA ±: 13.3%; anti-dsDNA −: 24.4%). The renal involvement was signifiantly more frequent in anti-dsDNA + (30.2%), compared with antidsDNA ± and anti-dsDNA − (21.1% and 18.7%, resp.; = 0.001). Serositis resulted signifiantly more frequent in anti-dsDNA − (82.3%) compared to anti-dsDNA + and anti-dsDNA ± (20.8% and 13.4%, resp.; < 0.0001). Th reduction of C4 serum levels was identified significantly more frequently in anti-dsDNA + and anti-dsDNA ± (40.0% and 44.2%, resp.) compared with antidsDNA − (21.8%, = 0.005). We did not identify significant differences in the mean ECLAM values before and after modifiation of anti-dsDNA status ( = 0.7). Conclusion. Anti-dsDNA status influences the clinical and immunological features of SLE patients. Nonetheless, it does not appear to affect disease activity

Comparison of Polyethylene Bubble Wrap and Corrugated Cardboard Traps for Sampling Tree-Inhabiting Spiders

In this paper, we studied the use of polyethylene bubble wrap and corrugated cardboard bark traps to sample spiders inhabiting tree trunks, with special reference to test whether they function the same way despite the differences in the spider community imposed by the different tree species and surroundings and times of sampling. The survey was carried out from July 1997 to July 1998 in Turin, Italy, in a green urban area on three poplars and four American basswoods. Differences between the two methods were tested in terms of abundance, diversity, dominance, mean body length of specimens, and proportion of juveniles, calculating Spearman's correlations. Three-factor analysis of variance, multiresponse permutation procedure, and indicator species analysis were used for further analysis. Results obtained by the two traps were correlated following a similar trend over sampling time. Bubble polyethylene seemed to be more effective than corrugated cardboard at trapping higher number of specimens. The dimension and total amount of interstices and the different microhabitat conditions of temperature and humidity seemed to be the main factors influencing spider composition in terms of the selected variables. On the basis of our results, polyethylene bark traps are recommended for sampling spiders living on trees. It is important to consider seasonality in experimental design, autumn being the period with the highest abundance of spiders but a lower level of diversity