4 research outputs found
Distribution of KIR/KIR-ligands co-presence in full responders (FR) and immunological non responders (INR). Analysis is adjusted for nadir CD4<sup>+</sup> T-cell counts.
<p><b>NOTE</b>. Data are numbers (no.) and percentages (%) of participants unless otherwise specified. Statistical significance is indicated by a P value of <0.05.</p><p>The presence of KIR-ligand genotype is considered <sup>+</sup> when observed in at least one allele: C1<sup>β</sup> β=β C1<sup>β/β</sup>; C1<sup>+</sup> β=β C1<sup>+/+</sup> or C1<sup>+/β</sup>; C2<sup>β</sup> β=β C2<sup>β/β</sup>; C2<sup>+</sup> β=β C2<sup>+/+</sup> or C2<sup>+/β</sup>; Cw*04<sup>β</sup> β=β Cw*04<sup>β/β</sup>; Cw*04<sup>+</sup> β=β Cw*04<sup>+/+</sup> or Cw*04<sup>+/β</sup>; Bw4<sup>β</sup> β=β Bw4<sup>β/β</sup>; Bw4<sup>+</sup> β=β Bw4<sup>+/+</sup> or Bw4<sup>+/β</sup>.</p><p>OR, Odds ratio; CI, Confidence Intervals; ND, not determined.</p
KIR alleles and haplotype frequencies distribution in full responders (FR), immunological non responders (INR), and in healthy controls as reference (HC). Analysis is adjusted for nadir CD4<sup>+</sup> T-cell counts.
<p><b>NOTE</b>. Data are no. (%) of participants unless otherwise specified. Statistical significance is indicated by a P value of <0.05. OR, Odds ratio; CI, Confidence Intervals.</p
Distribution of HLA B and C allele frequencies between immunological non responders (INR) and full responders (FR).
<p><b>NOTE</b>. Data are expressed as number (no.) of alleles and percentages (%) calculated on the total number of alleles per group (INR<b>β=β</b>100 alleles; FR<b>β=β</b>208 alleles). For each allele, the number of homozygous (h) subjects were reported. Statistical significance is indicated by a P value of <0.05.</p
Association study and meta-analysis for rs30187 in RRMS and CD.
a<p>P value from Pearson's Chi-squared test with Yates' continuity correction.</p>b<p>P value from Cochran Q heterogeneity test.</p>c<p>Heterogeneity index.</p>d<p>Random-effects meta-analysis p value.</p