Distribution of KIR/KIR-ligands co-presence in full responders (FR) and immunological non responders (INR). Analysis is adjusted for nadir CD4⁺ T-cell counts.

<p><b>NOTE</b>. Data are numbers (no.) and percentages (%) of participants unless otherwise specified. Statistical significance is indicated by a P value of <0.05.</p><p>The presence of KIR-ligand genotype is considered ⁺ when observed in at least one allele: C1⁻  =  C1^−/−; C1⁺  =  C1^+/+ or C1^+/−; C2⁻  =  C2^−/−; C2⁺  =  C2^+/+ or C2^+/−; Cw*04⁻  =  Cw*04^−/−; Cw*04⁺  =  Cw*04^+/+ or Cw*04^+/−; Bw4⁻  =  Bw4^−/−; Bw4⁺  =  Bw4^+/+ or Bw4^+/−.</p><p>OR, Odds ratio; CI, Confidence Intervals; ND, not determined.</p

KIR alleles and haplotype frequencies distribution in full responders (FR), immunological non responders (INR), and in healthy controls as reference (HC). Analysis is adjusted for nadir CD4⁺ T-cell counts.

<p><b>NOTE</b>. Data are no. (%) of participants unless otherwise specified. Statistical significance is indicated by a P value of <0.05. OR, Odds ratio; CI, Confidence Intervals.</p

Distribution of HLA B and C allele frequencies between immunological non responders (INR) and full responders (FR).

<p><b>NOTE</b>. Data are expressed as number (no.) of alleles and percentages (%) calculated on the total number of alleles per group (INR<b> = </b>100 alleles; FR<b> = </b>208 alleles). For each allele, the number of homozygous (h) subjects were reported. Statistical significance is indicated by a P value of <0.05.</p

Association study and meta-analysis for rs30187 in RRMS and CD.

a<p>P value from Pearson's Chi-squared test with Yates' continuity correction.</p>b<p>P value from Cochran Q heterogeneity test.</p>c<p>Heterogeneity index.</p>d<p>Random-effects meta-analysis p value.</p