Hypothetical prevalence curve (dots) for a successful STH elimination program, overlaid with program phase (diamond for transition points) and diagnostic use-cases.

<p>MDA, mass drug administration; STH, soil-transmitted helminth.</p

General desired characteristics of use-case #3 and #4 biomarkers.

<p>General desired characteristics of use-case #3 and #4 biomarkers.</p

Classes of intensity, based on Kato-Katz measurements [1].

<p>Classes of intensity, based on Kato-Katz measurements [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0006213#pntd.0006213.ref001" target="_blank">1</a>].</p

Planning processes for product development.

<p>Planning processes for product development.</p

Limitations and opportunities for improving coproscopy, with the Kato-Katz method as a predicate technique.

<p>Limitations and opportunities for improving coproscopy, with the Kato-Katz method as a predicate technique.</p

Diagnostic use-cases, described by program decision algorithm.

<p>Dashed box indicates a decision not described under current WHO guidelines for controlling STH morbidity but that may be important for a program aiming to eliminate transmission of STH. Dx, diagnostic; KK, Kato-Katz; MDA, mass drug administration; SAC, school-aged children; STH, soil-transmitted helminth.</p