Correlation between pandemic A/H1N1 and seasonal A/H1N1 neutralizing titers.

<p>Neutralizing titers are expressed as the log₁₀ of the geometric mean of titers calculated as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0011036#s4" target="_blank">Materials and Methods</a> in two independent experiments. Linear regression curve (continuous line) and 95%CI (dotted line) are presented. The correlation coefficient and P value were calculated by Spearman test.</p

Comparison of pandemic A/H1N1 neutralizing titers in subjects according to age.

<p>Symbols and P values are the same as those on <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0011036#pone-0011036-g002" target="_blank">figure 2</a>.</p

Changes in neutralizing and HI titers after pandemic A/H1N1 vaccination.

<p>*p<0.0001 vs baseline.</p

Comparison of pandemic A/H1N1 neutralizing titers in subjects vaccinated or not against seasonal influenza during the 2008–2009 epidemic season.

<p>Box and whiskers plots present the median, first and third quartile of the distribution (box) and outer whiskers extend the whole range of data. P values are from a Wilcoxon rank sum test.</p

French adaptation and validation of the Chronic Otitis Media Questionnaire-12 (COMQ-12)

Chronic otitis media (COM) can seriously impact quality of life (QOL). Disease-specific questionnaires are essential for an accurate assessment of this impact. There is no questionnaire available for French-speaking patients with COM. This study aims to adapt and validate the French version of the COMQ-12 questionnaire. This is a controlled, prospective study, conducted between May 2020 and December 2021. Translation was performed using a forward-backward technique, and statistical validation was performed with a COM patients and a controls adult cohorts. 100 patients (mean age 48 ± 16), and 50 controls (mean age 41 ± 16; p = 0.02) completed the test. Internal consistency, assessed by Cronbach’s alpha, was 0.870 for the cases group. The mean COMQ-12 total score was 23.92 ± 11.3 for cases versus 3.70 ± 6.15 for controls (p  The French version of the COMQ-12 is a short and easy-to-use test, with robust statistical properties, for assessing QOL in patients with COM.</p

Weekly rate of endonasal swabs positive for H1N1v pandemic influenza virus.

<p>Percentage of H1N1v positive endonasal swabs are indicated for each hospital (SLS: open circle, TRS: open square) and for both (plain black triangle and black dotted line). The national weekly rate from data provided by the GROG network is indicated by a grey dotted line and plain grey circles. The epidemic status of H1N1v was proclaimed in France by health authorities during the second week of September (black arrow).</p

Technical characteristic of EU-approved HIV screening rapid tests for use on whole blood and/or oral fluid.

<p>Technical characteristic of EU-approved HIV screening rapid tests for use on whole blood and/or oral fluid.</p

Clinical characteristics of patients with respiratory samples positive for H1N1v, positive for other respiratory pathogens or negative.

<p>*w/: presence of the clinical sign,</p>†<p>w/o: absence of the clinical sign,</p>‡<p>N/A: not available.</p>§<p>These data include the three patients whose respiratory samples could not be studied with the multiplex assay because of RT-PCR inhibitors.</p>∥<p>Comparison between the three groups of patients (with respiratory samples respectively positive for H1N1v, positive for other respiratory pathogens or negative). If p value is significant (<0.05), patients positive for H1N1v are compared with patients positive for other respiratory pathogens ^(¶) and with patients without any detection of respiratory pathogens ^(**).</p>††<p>Significant p values (<0.05) are indicated in bold.</p

Phylogenetic analysis of HIV-1 sequences.

<p><b>a)</b> Maximum likelihood tree inferred from the 190 concatenated group O sequences, with white diamonds at nodes with bootstrap values >70 and colours highlighting the nature of the residue at position 181 in the Reverse Transcriptase: Pink = C (N = 116); Green = Y (N = 71); Blue = mixed Y and C (N = 3); Grey = sequences from patients non NNRTI-naïve or with no data about NNRTI treatment. <b>b)</b> Maximum likelihood tree inferred from the 190 concatenated group M sequences.</p

Sensitivity of rapid test detection according to the HIV genotype.

<p>*Failure from PCR, serotyping insufficient volume in one sample;</p><p>**HIV-1 Subtype non B: A (3); D (2); F (2); J (1); O (1); CRF01 (3); CRF02 (17); CRF06 (1); CRF19 (1); Recombinant B/CRF02 (1); Complex recombinant (2); Serotyped as non B (24). Fischer exact test, p>0.25.</p