Study population at baseline.

<p>Values expressed as mean (SD) or n (%). BMI = body mass index, LTOT = long-term oxygen therapy, OHS = obesity hypoventilation syndrome, ICU = intensive care unit, FEV₁ = forced expiratory volume in 1 s, FVC = forced vital capacity, IPAP = inspiratory partial airway pressure, EPAP = expiratory partial airway pressure, Min RR = minimal respiratory rate</p><p>Study population at baseline.</p

Predictive factors for adherence in patients aged ≥ 75.

<p>OHS: obesity hypoventilation syndrome, MMSE: mini mental state examination</p><p>Predictive factors for adherence in patients aged ≥ 75.</p

Comparison of NIV efficacy at 6 months in patients aged < 75 years or ≥ 75 years.

<p>Δ: variation between baseline and 6 months</p><p>*p value < 0.05</p><p>^†percentage of patients with initial Epworth scale score over 10</p><p>^§ percentage of patients with initial Pittsburgh sleep quality index over 7</p><p>^‡p value for comparison of Δ between ≥ 75 and < 75</p><p>ESS: Epworth scale score, PSQI: Pittsburgh sleep quality index</p><p>Comparison of NIV efficacy at 6 months in patients aged < 75 years or ≥ 75 years.</p

Comparison of the impact of NIV on HRQL evaluated by SF-36 in patients aged < 75 years or ≥ 75 years.

<p>Values expressed as mean (SD).</p><p>Δ: variation between baseline and 6 months</p><p>*p value < 0.05</p><p>^‡p value for comparison of Δ between ≥ 75 and < 75</p><p>PCS: physical component summary, MCS: mental component summary</p><p>Comparison of the impact of NIV on HRQL evaluated by SF-36 in patients aged < 75 years or ≥ 75 years.</p

Baseline characteristics of adherent and non-adherent patients.^*

<p>*Results presented as mean (standard deviation) unless otherwise indicated.</p><p>Adherent patients: continuous positive airway pressure (CPAP) use ≥4 h/night.</p><p>Non-adherent patients: CPAP refused or abandoned, or CPAP use<4 h/night.</p><p>Significant level for p value: <0.05.</p

Flow diagram of subjects during the study.

<p>Abbreviations: CPAP: continuous positive airway pressure; IRSR, Institut de Recherche en Santé Respiratoire des Pays de la Loire.</p

Stepwise regression analysis of variables influencing CPAP adherence.

<p>Abbreviations: CPAP, continuous positive airway pressure; AHI, apnea-hypopnea index;</p><p>CPAP adherence: CPAP use ≥4 h/night.</p><p>Significant level for p value: <0.05.</p><p>Area under the ROC: 0.607.</p