2 nd Brazilian Consensus on Chagas Disease, 2015

Abstract Chagas disease is a neglected chronic condition with a high burden of morbidity and mortality. It has considerable psychological, social, and economic impacts. The disease represents a significant public health issue in Brazil, with different regional patterns. This document presents the evidence that resulted in the Brazilian Consensus on Chagas Disease. The objective was to review and standardize strategies for diagnosis, treatment, prevention, and control of Chagas disease in the country, based on the available scientific evidence. The consensus is based on the articulation and strategic contribution of renowned Brazilian experts with knowledge and experience on various aspects of the disease. It is the result of a close collaboration between the Brazilian Society of Tropical Medicine and the Ministry of Health. It is hoped that this document will strengthen the development of integrated actions against Chagas disease in the country, focusing on epidemiology, management, comprehensive care (including families and communities), communication, information, education, and research

The Potential of Red Propolis to Improve the Quality of Quail Eggs

ABSTRACT This study investigated the effects of dietary aqueous extract of red propolis (AERP) on the performance, egg quality, antioxidant capacity, and fecal microbiota of laying quails. A total of 120 52-day-old laying quails were randomly divided into four dietary treatments, each consisting of six replicates of 5 animals. The dietary treatments were a control basal diet and basal diets with of 1g of AERP, 2g of AERP, and 0.01g of enramycin per kg of feed for 63 days. Productive performance results such as percentage of egg production, feed intake per quail per day, average egg weight, egg mass, and feed conversion rate showed no significant difference between treatments. On the other hand, eggs from quails fed with red propolis showed darker yolk, higher intensity of red, and lower intensity of yellow (p<0.05); as well as lower pH in the yolk. Moreover, microbiological counts on the surface of eggs and feces from diets containing propolis were lower in comparison with other treatments. It is possible to conclude that 1 g of AERP showed promising results as a feed additive for laying quails, since it maintained the productive performance of these animals and caused qualitative enhancements in the physicochemical and microbiological characteristics of the eggs. Therefore, it could be used as a more natural way to improve quails’ egg production

Síndrome de turcot relato de dois casos

Os autores descrevem dois pacientes com associação de polipose intestinal e tumor do sistema nervoso central (síndrome de Turcot), discutindo aspectos clínicos, genéticos e terapêuticos

Alta parasitemia pelo Trypanosoma cruzi em paciente com lupus eritematoso sistêmico Trypanosoma cruzi high parasitemia in patient with systemic lupus erythematosus

É descrito um caso de doença de Chagas com alta parasitemia pelo Trypanosoma cruzi em paciente com lupus eritematoso sistêmico. O xenodiagnóstico foi útil na identificação da parasitemia e o benznidazol foi capaz de reduzir a alta e incomum parasitemia. Em indivíduos com doenças auto-imunes e immunossuprimidos, o benznidazol pode ser uma alternativa no controle da alta parasitemia por Trypanosoma cruzi.<br>A case of Trypanosoma cruzi high parasitemia in patient with systemic lupus erythematosus is reported. A xenodiagnostic test was useful in the identification of high and uncommon parasitemia, and Benznidazole was able to reduce the parasitemia. Benznidazole can be an alternative to control the Trypanosoma cruzi high parasitemia in people with autoimmune disease and immunosuppression