The Struggle is Real for large ensemble

Program Note: The art of composition is frequently difficult and discouraging. It is a struggle to create something new and true, even with the awareness of all the music that has come before and that is currently being created. The layered voices of self-criticism and doubt can be overwhelming. In some of my most frustrated moments, I started thinking about how many of the great masterpieces of classical music are about struggle: a struggle toward resolution, peace or revelation. In many of these pieces, the conflict is represented through dense counterpoint and fugal procedures, and I decided to appropriate some of the same methods. The resulting piece, while in some ways traditional and Romantic, feels like a fitting tribute to my own struggles and conflicts. The title is a phrase that has come into use recently to refer ironically to petty problems, but here I mean it in absolute sincerity. The struggle is real

Concordance groups of links

We define a notion of concordance based on Euler characteristic, and show that it gives rise to a concordance group of links in the 3-sphere, which has the concordance group of knots as a direct summand with infinitely generated complement. We consider variants of this using oriented and nonoriented surfaces as well as smooth and locally flat embeddings

Design of new highly functional polymer grafted polyhipes for proteins immobilization

PolyHIPE have proven to be useful in a large variety of applications included column filtration/separation, supported organic chemistry, as media for tissue engineering and 3D cell culture.1 The ability to conveniently modify pHIPE surfaces with functional groups is essential to opening new applications areas. The most promising method to conveniently modify pHIPE surface with a high density of functional groups is the “grafting from” approach. Stable polymer brushes covalently attached to the surface posses excellent mechanical and chemical robustness and offer the flexibility to introduce a large variety of functional monomers.2 We developed a new and unique pHIPE platform by incorporation of a polymerizable monomer with amino group into the HIPE available for different post in situ polymerization. The pHIPE with amino groups on the surface (pHIPE-NH2) can be directly used for the ring opening polymerization of amino acids N-carboxyanhydrates (NCAs) monomers to make pHIPE-g-polypeptide (such as pHIPE-g-poly(L-Benzyl Glutamate)) or easily converted to an atom transfer radical polymerization (ATRP) initiator for activators generated electron transfer (AGET) ATRP of tert-Butyl acrylate monomers. The polymers grafted can be deprotected to form pHIPE-g-poly(glutamic acid) or pHIPE-g-poly(acrylic acid) with reactive groups, on the surface of the pHIPE, available for further bioconjugation

A Patchwork Safety Net: A Survey of Cliometric Studies of Income Maintenance Programs in the United States in the First Half of the Twentieth Century

Social welfare programs in the United States are designed to serve as safety nets for people in hard times, in contrast with the universal approach found in many other developed western nations. In a survey of Cliometric studies of social welfare programs in the U.S., we examine the variation in the safety net in the U.S. across states in the 20th century, the determinants of the variation, and its impact on socioeconomic outcomes. The U.S. has always displayed substantial variation in the extent of the safety net because the features of most public social welfare programs are and were determined by local and state governments, even after the federal government became involved. Differences across states persist strongly for typically a decade, although the persistence weakens with time, and there are some periods when federal intervention led to a re-ordering. The rankings of state benefits differs from program to program, and economic and political factors have different weights in determining benefit levels in panel data estimation of their effects. Variation in benefits across programs during the early 1900s had significant impact on labor markets, economic activity, family formation, death rates, and crime.