Theory of mind, empathy and emotion perception in cortical and subcortical neurodegenerative diseases

Although the impact of neurodegenerative diseases on everyday interactions is well known in the literature, their impact on social cognitive processes remains unclear. The concept of social cognition refers to a set of skills, all of which are essential for living in a community. It involves social knowledge, perception and processing of social cues, and representation of mental states. This report is a review of recent findings on the impact of cortical and subcortical neurodegenerative diseases on three social cognitive processes, namely, the theory of mind, empathy and processing emotions. The focus here is on a conceptual approach to each of these skills and their cerebral underpinnings

Social cognition in normal and pathological aging

The concept of social cognition refers to a set of skills and to emotional and social experiences regulating relationships between individuals. This concept is appropriate in order to help us to explain individual human behaviours and behaviours in groups. Social cognition involves social knowledge, perception and processing of social cues, and the representation of mental states. The concept of social cognition thus refers to a multitude of skills. This paper stops on several of them, namely theory of mind, empathy, moral reasoning, emotional processing and emotional regulation. We propose a conceptual approach to each of these skills also stopping on their cerebral underpinnings. We also make an inventory of knowledge about the effects of age and neurodegenerative diseases on social cognition

Neuropsychologie et cognition sociale

La notion de cognition sociale fait référence à l’ensemble des aptitudes et expériences émotionnelles et sociales régulant les relations entre les individus et permettant d’expliquer les comportements humains individuels ou en groupe. Elle implique des connaissances sociales, la perception et le traitement de signaux sociaux, ainsi que la représentation des états mentaux. La notion de cognition sociale renvoie donc à de multiples aptitudes. Ce chapitre s\u27arrête sur plusieurs d\u27entre-elles, à savoir la théorie de l\u27esprit, l\u27empathie, le raisonnement et le jugement moral. Nous proposons une approche conceptuelle de chacune de ces aptitudes en nous appuyant, pour une large part, sur les travaux développés dans le champ de la neuropsychologie humaine. Nous nous arrêtons également sur les soubassements neuro-anatomiques de chacune de ces aptitudes

Observation and absolute frequency measurements of the 1S0 - 3P0 optical clock transition in ytterbium

We report the direct excitation of the highly forbidden (6s^2) 1S0 - (6s6p) 3P0 optical transition in two odd isotopes of ytterbium. As the excitation laser frequency is scanned, absorption is detected by monitoring the depletion from an atomic cloud at ~70 uK in a magneto-optical trap. The measured frequency in 171Yb (F=1/2) is 518,295,836,593.2 +/- 4.4 kHz. The measured frequency in 173Yb (F=5/2) is 518,294,576,850.0 +/- 4.4 kHz. Measurements are made with a femtosecond-laser frequency comb calibrated by the NIST cesium fountain clock and represent nearly a million-fold reduction in uncertainty. The natural linewidth of these J=0 to J=0 transitions is calculated to be ~10 mHz, making them well-suited to support a new generation of optical atomic clocks based on confinement in an optical lattice.Comment: 4 pages, 3 figure

Observation of the 1S0 - 3P0 clock transition in 27Al+

We report for the first time, laser spectroscopy of the 1S0 - 3P0 clock transition in 27Al+. A single aluminum ion and a single beryllium ion are simultaneously confined in a linear Paul trap, coupled by their mutual Coulomb repulsion. This coupling allows the beryllium ion to sympathetically cool the aluminum ion, and also enables transfer of the aluminum's electronic state to the beryllium's hyperfine state, which can be measured with high fidelity. These techniques are applied to a measurement of the clock transition frequency, \nu = 1 121 015 393 207 851(8) Hz. They are also used to measure the lifetime of the metastable clock state, \tau = 20.6 +/- 1.4 s, the ground state 1S0 g-factor, g_S = -0.00079248(14), and the excited state 3P0 g-factor, g_P = -0.00197686(21), in units of the Bohr magneton.Comment: 4 pages, 2 figures; updated author lis

Characterisation of the clinical importance of porcine group C rotavirus in a swine nursery production network in Quebec

Enteric infectious diseases in swine have considerable economic impact on the industry due either to mortality, cost of treatment or reduced growth rates which can lead to extended production periods. The consequences can be catastrophic especially in nursery sites since young piglets are in a susceptible period associated with immature immune system and are often affected by rapid dehydration related to neonatal diseases

Comparison of low--energy resonances in 15N(alpha,gamma)19F and 15O(alpha,gamma)19Ne and related uncertainties

A disagreement between two determinations of Gamma_alpha of the astro- physically relevant level at E_x=4.378 MeV in 19F has been stated in two recent papers by Wilmes et al. and de Oliveira et al. In this work the uncertainties of both papers are discussed in detail, and we adopt the value Gamma_alpha=(1.5^{+1.5}_{-0.8})10^-9eV for the 4.378 MeV state. In addition, the validity and the uncertainties of the usual approximations for mirror nuclei Gamma_gamma(19F) approx Gamma_gamma(19Ne), theta^2_alpha(19F) approx theta^2_alpha(19Ne) are discussed, together with the resulting uncertainties on the resonance strengths in 19Ne and on the 15O(alpha,gamma)19Ne rate.Comment: 9 pages, Latex, To appear in Phys. Rev.

Neuropsychologie et technologies numériques

Digital technologies have made particularly spectacular progress in recent decades, providing clinicians with new tools for neuropsychological assessment and revalidation (software for neuropsychological assessment and revalidation, virtual reality, digital external aids, tele-neuropsychology), which can significantly change their practices. This article proposes a general, critical, and illustrated reflection centered on the state of technological adaptation in the field of clinical neuropsychology. To do this, we will focus on the significance and limitations of traditional clinical neuropsychology (Neuropsychology 1.0), computer-assisted neuropsychology (Neuropsychology 2.0), neuropsychology based on virtual environments (Neuropsychology 3.0), and tele-neuropsychology. This reflection raises a number of scientific, technical, practical and ethical questions that we hope will provoke debate within our community.