15,217 research outputs found
Anomalous diffusion in quantum Brownian motion with colored noise
Anomalous diffusion is discussed in the context of quantum Brownian motion
with colored noise. It is shown that earlier results follow simply and directly
from the fluctuation-dissipation theorem. The limits on the long-time
dependence of anomalous diffusion are shown to be a consequence of the second
law of thermodynamics. The special case of an electron interacting with the
radiation field is discussed in detail. We apply our results to wave-packet
spreading
Quantum Field Theory Constrains Traversable Wormhole Geometries
Recently a bound on negative energy densities in four-dimensional Minkowski
spacetime was derived for a minimally coupled, quantized, massless, scalar
field in an arbitrary quantum state. The bound has the form of an uncertainty
principle-type constraint on the magnitude and duration of the negative energy
density seen by a timelike geodesic observer. When spacetime is curved and/or
has boundaries, we argue that the bound should hold in regions small compared
to the minimum local characteristic radius of curvature or the distance to any
boundaries, since spacetime can be considered approximately Minkowski on these
scales. We apply the bound to the stress-energy of static traversable wormhole
spacetimes. Our analysis implies that either the wormhole must be only a little
larger than Planck size or that there is a large discrepancy in the length
scales which characterize the wormhole. In the latter case, the negative energy
must typically be concentrated in a thin band many orders of magnitude smaller
than the throat size. These results would seem to make the existence of
macroscopic traversable wormholes very improbable.Comment: 26 pages, plain LaTe
Nevirapine- and efavirenz-associated hepatotoxicity under programmatic conditions in Kenya and Mozambique.
To describe the frequency, risk factors, and clinical signs and symptoms associated with hepatotoxicity (HT) in patients on nevirapine- or efavirenz-based antiretroviral therapy (ART), we conducted a retrospective cohort analysis of patients attending the ART clinic in Kibera, Kenya, from April 2003 to December 2006 and in Mavalane, Mozambique, from December 2002 to March 2007. Data were collected on 5832 HIV-positive individuals who had initiated nevirapine- or efavirenz-based ART. Median baseline CD4+ count was 125 cells/ÎĽL (interquartile range [IQR] 55-196). Over a median follow-up time of 426 (IQR 147-693) days, 124 (2.4%) patients developed HT. Forty-one (54.7%) of 75 patients with grade 3 HT compared with 21 (80.8%) of 26 with grade 4 had associated clinical signs or symptoms (P = 0.018). Four (5.7%) of 124 patients with HT died in the first six months compared with 271 (5.3%) of 5159 patients who did not develop HT (P = 0.315). The proportion of patients developing HT was low and HT was not associated with increased mortality. Clinical signs and symptoms identified 50% of grade 3 HT and most cases of grade 4 HT. This suggests that in settings where alanine aminotransferase measurement is not feasible, nevirapine- and efavirenz-based ART may be given safely without laboratory monitoring
Quantum measurement and decoherence
Distribution functions defined in accord with the quantum theory of
measurement are combined with results obtained from the quantum Langevin
equation to discuss decoherence in quantum Brownian motion. Closed form
expressions for wave packet spreading and the attenuation of coherence of a
pair of wave packets are obtained. The results are exact within the context of
linear passive dissipation. It is shown that, contrary to widely accepted
current belief, decoherence can occur at high temperature in the absence of
dissipation. Expressions for the decoherence time with and without dissipation
are obtained that differ from those appearing in earlier discussions
Exponential Divergence and Long Time Relaxation in Chaotic Quantum Dynamics
Phase space representations of the dynamics of the quantal and classical cat
map are used to explore quantum--classical correspondence in a K-system: as
, the classical chaotic behavior is shown to emerge smoothly and
exactly. The quantum dynamics near the classical limit displays both
exponential separation of adjacent distributions and long time relaxation, two
characteristic features of classical chaotic motion.Comment: 10 pages, ReVTeX, to appear in Phys. Rev. Lett. 13 figures NOT
included. Available either as LARGE (uuencoded gzipped) postscript files or
hard-copies from [email protected]
Restrictions on Negative Energy Density in Flat Spacetime
In a previous paper, a bound on the negative energy density seen by an
arbitrary inertial observer was derived for the free massless, quantized scalar
field in four-dimensional Minkowski spacetime. This constraint has the form of
an uncertainty principle-type limitation on the magnitude and duration of the
negative energy density. That result was obtained after a somewhat complicated
analysis. The goal of the current paper is to present a much simpler method for
obtaining such constraints. Similar ``quantum inequality'' bounds on negative
energy density are derived for the electromagnetic field, and for the massive
scalar field in both two and four-dimensional Minkowski spacetime.Comment: 17 pages, including two figures, uses epsf, minor revisions in the
Introduction, conclusions unchange
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