The Relationship of Dynamic Indicators of Basic Early Literacy Skills (DIBELS) Oral Reading Fluency and the Terra Nova, 2nd Ed. Performance on Ohio Grade 3 Reading Achievement Assessment

The purpose of this study was to investigate the correlation between performance on the DIBELS ORF Benchmark 2, the Terra Nova, 2nd Ed., and reading proficiency on the Ohio Grade 3 Reading Achievement Test. The research question examined the wisdom of using both the DIBELS ORF Benchmark 2 Indicator and the Terra Nova, as predictors for the Ohio Grade 3 Reading Achievement Test. After gathering archival data for the 136 students involved, a Pearson-Product Moment Correlation was used to determine this correlation. Data was additionally analyzed using a Hits and Misses Table. Results produced a significant, positive correlation between DIBELS ORF scores, the Terra Nova, and the Ohio Third Grade Reading Achievement Test. This study demonstrates, however, administering the Terra Nova as an additional assessment from March through May provides marginal student benefit. This study identifies the effectiveness of using early identification to predict reading mastery on high-stakes reading tests

Mirrwana and wurrkama: applying an Indigenous knowledge framework to collaborative research on ceremonies

This chapter outlines how Ford, Barwick and Marett have collaborated to develop, implement, and critically evaluate a research project that integrates and remains true to both Indigenous and western academic knowledge systems. The context is the ceremonies of the Tyikim people from remote, rural and urban areas in the Wagait-Daly region of the Top End of Northern Territory, and in particular, the series of ceremonies that followed the death of Ford’s mother in 2007. We outline the processes of Indigenous and non-Indigenous collaboration that underpinned the performance and documentation of the ceremonies and, more specifically, how this process can be seen through the Indigenous knowledge framework mirrwana-wurrkama, developed by Ford based on her family’s traditional cycad nut processing practices.Australian Research Council DP0450131, DP109689

Muluk's Wangga

Jimmy Muluk (born c. 1925, died sometime before 1986) was one of the great wangga songmen, whose musical virtuosity and love of diversity and variation are exceeded by no other singer. A Mendheyangal man, he held traditional country around the Cape Ford area south of the Daly River mouth, but he lived most of his life in and around Belyuen on the Cox Peninsula. For many years he led a dance troupe presenting performances for tourists at Mica Beach, and later at Mandorah. He also mentored younger generations of singers to perform with him in public at tourist corroborees and the Darwin Eisteddfod. The success of his strategy for intergenerational transmission of knowledge was evident when Marett and Barwick recorded the same singers, now men, in the 1990s. Muluk’s mentee, Colin Worumbu Ferguson, leads the Kenbi dancers today

Ma-Yawa Wangga

The Ma-yawa wangga repertory was given to songmen by the Marri Ammu ancestral ghosts known as Ma-yawa. Before the late 1960s, it seems that this repertory was frequently performed at Wadeye, but nowadays Marri Ammu people join their Marri Tjavin neighbours in performing the Walakandha wangga repertory for ceremony. All but one of the Ma-yawa wangga songs were composed by the senior Marri Ammu lawman and artist Charlie Niwilhi Brinken (c. 1910–1993), but so far as we know, no recording was ever made of him singing. Maurice Tjakurl Ngulkur (Nyilco) (1940–2001), the Marri Ammu songman, inherited the repertory and added one of his own songs to it. Since his passing in 2001, the songs have rarely been performed. With its strong focus on the Dreamings (ngirrwat) and Dreaming sites (kigatiya) of the Marri Ammu people, the Ma-yawa wangga repertory holds a unique place within the corpus

Preface

Dissertação de mestrado (Quimica Farmacêutica Industrial), apresentada á Faculdade de Farmácia da Universidade de CoimbraA via ubiquitina-proteassoma desempenha um papel importante na homeostase celular, exercendo também um papel relevante na regulação de diversas vias celulares, incluindo no crescimento e na proliferação celular, na apoptose, na reparação do ADN, na transcrição e na resposta imune. O proteassoma é um complexo multienzimático que contém vários centros ativos, sendo a sua função principal degradar proteínas desnecessárias ou danificadas. Algumas patologias humanas devem-se a alterações nesta via. Como tal, a inibição da via ubiquitina-proteassoma por inibidores do proteassoma pode ser uma abordagem terapêutica racional para várias doenças, tais como o cancro e doenças inflamatórias. Com o objetivo de obter novos inibidores do proteassoma para o local ativo CT-L, foram utilizados os seguintes métodos computacionais: modelação por homologia, farmacóforos, docking e virtual screening. Foi desenvolvido e validado um modelo de homologia para o local ativo CT-L que teve como base o código PDB 3UN8. Na modelação farmacofórica, obtivemos e validámos dois modelos farmacofóricos: um modelo com base na estrutura de inibidores conhecidos do local ativo β5c e um modelo com base na estrutura do recetor. Na etapa de virtual screening foi efetuado o docking molecular tendo como base a estrutura de ligandos (no qual se utilizou o modelo farmacofórico obtido com base na estrutura de ligandos) e tendo como base a estrutura do recetor (sem a utilização de farmacóforos como filtro). Os resultados foram analisados de modo a selecionarmos potenciais compostos hitThe ubiquitin proteasome pathway plays an important role in cellular homeostasis and also it exerts a critical role in regulating a wide variety of cellular pathways, including cell growth and proliferation, apoptosis, DNA repair, transcription and immune response. The proteasome is a multienzyme complex, containing several active centers and the main function of the proteasome is to degrade unneeded or damaged proteins. Defects in this pathway have been implicated in a number of human pathologies. Inhibition of the ubiquitin-proteasome pathway by proteasome inhibitors may be a rational therapeutic approach for various diseases, such as cancer and inflammatory diseases. To obtain new proteasome inhibitors for the CT-L active site, were used the following computational methods: homology modeling, pharmacophores, docking and virtual screening. Using the PDB code 3UN8, it was developed and validated an homology model for the CT-L active site. In pharmacophoric modeling, we obtained and validated two pharmacophoric models: a model based in the structure of known inhibitors of the β5c active site and a model based in the receptor structure. In the virtual screening step, the molecular docking was made based in ligand structure (in which was used the pharmacophoric model ligand based) and based in the receptor structure (without the use of the pharmacophore as a filter). The results were analised so we can select potential hit compound

Primary Source Material in Science: The Importance of Archival Field Notes

Field notebooks are a gold mine of unpublished observations, journal notes, sketches, weather reports, specimen lists and travel narratives: these records are primary source data at its most raw and unevaluated. Historical collections of field notes may be the only documentation of a scientist’s thought processes, ideas and observations, particularly if only some of the material was ever published. As part of an IMLS National Leadership grant, the field notes of William Brewster, a highly published ornithologist working during the late 19th and early 20th centuries were digitized and made accessible via the Biodiversity Heritage Library portal. Along with digitizing specimens and other archival materials related to William Brewster, the notebooks allow easy access to his detailed notes and pioneering work in ornithology. The presentation of these notebooks enhances contemporary studies and makes the entire research cycle of this scientist’s work available for analysis by historians of science, scientists, social scientists and humanists or anyone interested in the process of discovery, by creating a richer and more interactive history of science resource. Who knows what ornithological preconceptions might be reconsidered if this body of work is fully available to contemporary researchers and citizen scientists? The purpose of this poster is to demonstrate the connections among Brewster’s field notes, specimens he collected, the publications that were the result of his work and current research, thus making a case for the value of archival research

Walakandha Wangga

For the last 40 years or so, the Walakandha wangga, a repertory composed collaboratively by a number of Marri Tjavin singers, has been the most prominent wangga performed in Wadeye. Initiated in the mid-1960s by Stan Mullumbuk (1937–1980), the Walakandha wangga repertory came to function as one arm of a tripartite ceremonial system organising ceremonial life at Wadeye, in complementary relationship with sister repertories djanba and lirrga. The dominant themes of the Walakandha wangga are related to the activities of the Marri Tjavin ancestral dead – the Walakandha – as givers of wangga songs and protectors of their living descendants. Longing for return to Marri Tjavin ancestral country is another common theme. Many specific places are named. Foremost among these is the hill Yendili – one of the places where Walakandha ancestors reside