411 research outputs found
Utility and lower limits of frequency detection in surface electrode stimulation for somatosensory brain-computer interface in humans
Objective: Stimulation of the primary somatosensory cortex (S1) has been successful in evoking artificial somatosensation in both humans and animals, but much is unknown about the optimal stimulation parameters needed to generate robust percepts of somatosensation. In this study, the authors investigated frequency as an adjustable stimulation parameter for artificial somatosensation in a closed-loop brain-computer interface (BCI) system.
Methods: Three epilepsy patients with subdural mini-electrocorticography grids over the hand area of S1 were asked to compare the percepts elicited with different stimulation frequencies. Amplitude, pulse width, and duration were held constant across all trials. In each trial, subjects experienced 2 stimuli and reported which they thought was given at a higher stimulation frequency. Two paradigms were used: first, 50 versus 100 Hz to establish the utility of comparing frequencies, and then 2, 5, 10, 20, 50, or 100 Hz were pseudorandomly compared.
Results: As the magnitude of the stimulation frequency was increased, subjects described percepts that were āmore intenseā or āfaster.ā Cumulatively, the participants achieved 98.0% accuracy when comparing stimulation at 50 and 100 Hz. In the second paradigm, the corresponding overall accuracy was 73.3%. If both tested frequencies were less than or equal to 10 Hz, accuracy was 41.7% and increased to 79.4% when one frequency was greater than 10 Hz (p = 0.01). When both stimulation frequencies were 20 Hz or less, accuracy was 40.7% compared with 91.7% when one frequency was greater than 20 Hz (p < 0.001). Accuracy was 85% in trials in which 50 Hz was the higher stimulation frequency. Therefore, the lower limit of detection occurred at 20 Hz, and accuracy decreased significantly when lower frequencies were tested. In trials testing 10 Hz versus 20 Hz, accuracy was 16.7% compared with 85.7% in trials testing 20 Hz versus 50 Hz (p < 0.05). Accuracy was greater than chance at frequency differences greater than or equal to 30 Hz.
Conclusions: Frequencies greater than 20 Hz may be used as an adjustable parameter to elicit distinguishable percepts. These findings may be useful in informing the settings and the degrees of freedom achievable in future BCI systems
The North Pacific Fur Seal Industry. The Record of International Management
The State of Alask
BK Lyncis: The Oldest Old Nova?... And a Bellwether for Cataclysmic-Variable Evolution
We summarize the results of a 20-year campaign to study the light curves of
BK Lyncis, a nova-like star strangely located below the 2-3 hour orbital period
gap in the family of cataclysmic variables. Two apparent "superhumps" dominate
the nightly light curves - with periods 4.6% longer, and 3.0% shorter, than
P_orb. The first appears to be associated with the star's brighter states
(V~14), while the second appears to be present throughout and becomes very
dominant in the low state (V~15.7).
Starting in the year 2005, the star's light curve became indistinguishable
from that of a dwarf nova - in particular, that of the ER UMa subclass.
Reviewing all the star's oddities, we speculate: (a) BK Lyn is the remnant of
the probable nova on 30 December 101, and (b) it has been fading ever since,
but has taken ~2000 years for the accretion rate to drop sufficiently to permit
dwarf-nova eruptions. If such behavior is common, it can explain other puzzles
of CV evolution. One: why the ER UMa class even exists (because all members can
be remnants of recent novae). Two: why ER UMa stars and short-period novalikes
are rare (because their lifetimes, which are essentially cooling times, are
short). Three: why short-period novae all decline to luminosity states far
above their true quiescence (because they're just getting started in their
postnova cooling). Four: why the orbital periods, accretion rates, and
white-dwarf temperatures of short-period CVs are somewhat too large to arise
purely from the effects of gravitational radiation (because the unexpectedly
long interval of enhanced postnova brightness boosts the mean mass-transfer
rate). These are substantial rewards in return for one investment of
hypothesis: that the second parameter in CV evolution, besides P_orb, is time
since the last classical-nova eruption.Comment: PDF, 46 pages, 4 tables, 10 figures; in preparation; more info at
http://cbastro.org
Utility and lower limits of frequency detection in surface electrode stimulation for somatosensory brain-computer interface in humans
Objective: Stimulation of the primary somatosensory cortex (S1) has been successful in evoking artificial somatosensation in both humans and animals, but much is unknown about the optimal stimulation parameters needed to generate robust percepts of somatosensation. In this study, the authors investigated frequency as an adjustable stimulation parameter for artificial somatosensation in a closed-loop brain-computer interface (BCI) system.
Methods: Three epilepsy patients with subdural mini-electrocorticography grids over the hand area of S1 were asked to compare the percepts elicited with different stimulation frequencies. Amplitude, pulse width, and duration were held constant across all trials. In each trial, subjects experienced 2 stimuli and reported which they thought was given at a higher stimulation frequency. Two paradigms were used: first, 50 versus 100 Hz to establish the utility of comparing frequencies, and then 2, 5, 10, 20, 50, or 100 Hz were pseudorandomly compared.
Results: As the magnitude of the stimulation frequency was increased, subjects described percepts that were āmore intenseā or āfaster.ā Cumulatively, the participants achieved 98.0% accuracy when comparing stimulation at 50 and 100 Hz. In the second paradigm, the corresponding overall accuracy was 73.3%. If both tested frequencies were less than or equal to 10 Hz, accuracy was 41.7% and increased to 79.4% when one frequency was greater than 10 Hz (p = 0.01). When both stimulation frequencies were 20 Hz or less, accuracy was 40.7% compared with 91.7% when one frequency was greater than 20 Hz (p < 0.001). Accuracy was 85% in trials in which 50 Hz was the higher stimulation frequency. Therefore, the lower limit of detection occurred at 20 Hz, and accuracy decreased significantly when lower frequencies were tested. In trials testing 10 Hz versus 20 Hz, accuracy was 16.7% compared with 85.7% in trials testing 20 Hz versus 50 Hz (p < 0.05). Accuracy was greater than chance at frequency differences greater than or equal to 30 Hz.
Conclusions: Frequencies greater than 20 Hz may be used as an adjustable parameter to elicit distinguishable percepts. These findings may be useful in informing the settings and the degrees of freedom achievable in future BCI systems
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