A avaliação perceptiva de atributos paralinguísticos e extralinguísticos na fala de uma comunidade de prática

Este trabalho tem como objetivo investigar as impressões causadas, pelo falar de sujeitos de uma comunidade de prática caiçara, em grupos de ouvintes de três localidades diversas, por meio da aplicação de um questionário de diferencial semântico, o qual contém descritores referentes a atributos paralinguísticos e extralinguísticos: psicológicos, sociais, culturais, físicos e econômicos. Trata-se de uma pesquisa de natureza sociofonética perceptiva que compreende uma tarefa de produção e uma de percepção e utiliza o método de análise estatística multidimensional. Os resultados indicam que a fala da comunidade caiçara não causou nenhuma estranheza ou incompreensão, mas foi considerada pouco agradável pelos juízes de todas as localidades. Com base nas variáveis estatisticamente significantes, os caiçaras, a partir da percepção da sua maneira de falar, foram julgados como pessoas que exercem trabalhos manuais, apresentam situação financeira baixa e são ingênuos, simplórios e humildes

Imigrantes russos no Brasil: para entender, para ser compreendido

While L2 acquisition by Brazilians has been studied for different languages, the acquisition of Brazilian Portuguese by foreigners has been poorly explored. Recent studies of non-native accented speech in other languages have shown that a foreign accent could largely influence the perception of personal qualities of speakers, and this issue presents a large interest for intercultural research projects. Our research project is focused on Russophone immigrants living in Brazil, bilingual speakers of Russian and Portuguese. The specific aim of the current work is to describe a database containing information about 40 native Russian speakers living in São Paulo for at least six months. Their linguistic and sociocultural profiles are presented, and the experimental protocol of the data collection is described. The protocol included recording speech samples in Russian and in Portuguese and video recordings for further facial expression analysis of bilinguals by the program FaceReader 7.0. The analysis of the sociocultural profiles of the Russophones, presented in the current work, provides a strong basis for the enrichment of the phonetic, sociolinguistic, and nonverbal behavior analysis of these speakers.A aquisição de L2 por brasileiros tem sido foco de um grande número de estudos. No entanto, a aquisição de português brasileiro por falantes de outras línguas tem sido pouco explorada. Pesquisas recentes sobre o sotaque estrangeiro mostram que este pode exercer forte influência na percepção de características pessoais de falantes, fator este que se reveste de grande interesse em projetos de pesquisa de natureza intercultural. O nosso projeto de pesquisa tem como foco imigrantes russófonos que moram no Brasil, falantes bilíngues de russo e português. O objetivo específico deste trabalho é descrever um banco de dados que contém informação sobre 40 falantes nativos de russo que moram em São Paulo há pelo menos 6 meses. Descrevemos seus perfis linguísticos e socioculturais, e apresentamos o protocolo de coleta de dados desenvolvido. O protocolo inclui a gravação de amostras de fala em russo e em português, e também a gravação em vídeo para futura análise de expressões faciais em bilingues, utilizando o programa FaceReader 7.0. A análise de perfis socioculturais de russófonos, apresentada no presente trabalho, fornece subsídios para enriquecer as análises fonéticas, sociolinguísticas e de comportamento não-verbal desses falantes

One binge-type cycle of alcohol plus ketamine exposure induces emotional-like disorders associated with oxidative damage in adolescent female rats

This work is supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES-FINANCE CODE 001); Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq/ Brazil for her Research Productivity Grant (number 311335/2019–5 to CSFM); R.R.L. is a researcher from the CNPq, under grant number 312275/ 2021–8. Research Pro-Rectory of the Federal University of Pará (PROPESP, UFPA, Brazil).Federal University of Pará. Institute of Health Science. Faculty of Pharmacy. Laboratory of Pharmacology of Inflammation and Behavior. Belém, PA, Brazil.Federal University of Pará. Institute of Health Science. Faculty of Pharmacy. Laboratory of Pharmacology of Inflammation and Behavior. Belém, PA, Brazil.Federal University of Pará. Institute of Health Science. Faculty of Pharmacy. Laboratory of Pharmacology of Inflammation and Behavior. Belém, PA, Brazil.Federal University of Pará. Institute of Health Science. Faculty of Pharmacy. Laboratory of Pharmacology of Inflammation and Behavior. Belém, PA, Brazil.Federal University of Pará. Institute of Health Science. Faculty of Pharmacy. Laboratory of Pharmacology of Inflammation and Behavior. Belém, PA, Brazil.University of Pará State. Center for Biological and Health Sciences. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Science. Laboratory of Pharmacology and Toxicology of Cardiovascular System. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Laboratory of Functional and Structural Biology. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Laboratory of Functional and Structural Biology. Belém, PA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Instituto Evandro Chagas. Laboratório de Citogenômica e Mutagênese Ambiental. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Instituto Evandro Chagas. Laboratório de Citogenômica e Mutagênese Ambiental. Ananindeua, PA, Brasil.Ophir Loyola Hospital. Laboratory of Molecular Biology. Belém, PA, Brazil.Ophir Loyola Hospital. Laboratory of Molecular Biology. Belém, PA, Brazil.Federal University of Pará. Institute of Health Science. Faculty of Pharmacy. Laboratory of Pharmacology of Inflammation and Behavior. Belém, PA, Brazil.Federal University of Pará. Institute of Health Science. Faculty of Pharmacy. Laboratory of Pharmacology of Inflammation and Behavior. Belém, PA, Brazil.Drug abuse is a global public health problem among adolescents, with alcohol often used in association with other psychotropic drugs, such as ketamine. Considering the scarcity of evidence, this study aimed to investigate emotional behavioral effects induced by ethanol plus ketamine co-abuse, as well as oxidative biochemistry, and neurotrophic mediator in the prefrontal cortex and hippocampus in the early withdrawal of adolescent female rats. Animals were divided into control, ethanol, ketamine, and ethanol plus ketamine groups. The protocol administration was performed for 3 consecutive days (binge-like pattern). Behavioral assays of open field, elevated plus maze, and forced swim test were performed. After that, the prefrontal cortex and hippocampus were collected to evaluate oxidative biochemistry (reactive oxygen species-ROS; Antioxidant capacity against peroxyl radicals-ACAP; and lipid peroxidation). We found that isolated or combined ethanol and ketamine exposure displayed anxiety- and depressive-like profile, in a non-synergistically manner during early withdrawal. However, oxidative damage was aggravated in the co-administered animals than in isolated exposed subjects. We concluded that ethanol plus ketamine co-abuse may intensify oxidative damage in the hippocampus and prefrontal cortex in the early withdrawal of adolescent female rats, which was not reflected in the emotional behavioral phenotype

One binge-type cycle of alcohol plus ketamine exposure induces emotional-like disorders associated with oxidative damage in adolescent female rats

Drug abuse is a global public health problem among adolescents, with alcohol often used in association with other psychotropic drugs, such as ketamine. Considering the scarcity of evidence, this study aimed to investigate emotional behavioral effects induced by ethanol plus ketamine co-abuse, as well as oxidative biochemistry, and neurotrophic mediator in the prefrontal cortex and hippocampus in the early withdrawal of adolescent female rats. Animals were divided into control, ethanol, ketamine, and ethanol plus ketamine groups. The protocol administration was performed for 3 consecutive days (binge-like pattern). Behavioral assays of open field, elevated plus maze, and forced swim test were performed. After that, the prefrontal cortex and hippocampus were collected to evaluate oxidative biochemistry (reactive oxygen species-ROS; Antioxidant capacity against peroxyl radicals-ACAP; and lipid peroxidation). We found that isolated or combined ethanol and ketamine exposure displayed anxiety- and depressive-like profile, in a non-synergistically manner during early withdrawal. However, oxidative damage was aggravated in the co-administered animals than in isolated exposed subjects. We concluded that ethanol plus ketamine co-abuse may intensify oxidative damage in the hippocampus and prefrontal cortex in the early withdrawal of adolescent female rats, which was not reflected in the emotional behavioral phenotype. Data availability statement: The datasets used and/or analyzed during the current investigation are available upon reasonable request from the corresponding author