12,617 research outputs found

    Is there a relationship between the lean concept and productivity rate of construction projects?

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    Copyright © 2011 by Research Publishing Services. This paper seeks to show whether the implementation of the lean concept within the UK construction industry has an impact on the productivity rate of projects. 37 UK construction Project Directors and Project Managerswere surveyed and the result shows that the lean concept is making considerable headway in improving productivity of UK construction projects. There is a strong correlation between high leanness and high productivity rates on UK construction projects. The results also indicated that there is no significant difference between the application of the lean concept between the manufacturing and the construction industry

    The EDGES signal: An imprint from the mirror world?

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    Recent results from the Experiment to Detect the Global Epoch of Reionization Signature (EDGES) show an anomalous spectral feature at redshifts z1520z\sim 15-20 in its 21-cm absorption signal. This deviation from cosmological predictions can be understood as a consequence of physics that either lower the hydrogen spin temperature or increases the radiation temperature through the injection of soft photons in the bath. In the latter case, standard model neutrino decays νiνjγ\nu_i \to \nu_j\,\gamma induced by effective magnetic and electric transition moments (μeff\mu_\text{eff}) are precluded by the tight astrophysical constraints on μeff\mu_\text{eff}. We show that if mirror neutrinos are present in the bath at early times, an analogous mechanism in the mirror sector can lead to a population of mirror photons that are then "processed" into visible photons through resonant conversion, thus accounting for the EDGES signal. We point out that the mechanism can work for mirror neutrinos which are either heavier than or degenerate with the standard model (SM) neutrinos, a scenario naturally realized in mirror twin Higgs models.Comment: 8 pages, 2 figure

    Whistleblower Protection and the Office of Special Counsel: The Development of Reprisal Law in the 1980s

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    The Distinction of the Interactions Between the Transmembrane Domains of Basigin Gene Products and Monocarboxylate Transporters

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    Although it was once thought that neurons solely rely on glucose as a substrate for cellular energy production, it is now known that small monocarboxylate molecules, like pyruvate, lactate, and ketone bodies, are also utilized. Monocarboxylates are transported across plasma membranes via facilitated diffusion using a family of transport proteins known as monocarboxylate transporters (MCTs). Four MCTs (MCT1, MCT2, MCT3, and MCT4) are expressed within neural tissues. Expression of the MCTs has been tied to co-expression of a cell adhesion molecule belonging to the Basigin subset of the immunoglobulin superfamily (IgSF). Basigin gene products are known to interact with MCT1 and MCT4 in the mammalian neural retina and this association is essential to support the cellular energy needs of photoreceptors. A previous study indicated that Basigin gene products use hydrophobic amino acids within specific regions of the transmembrane domain to interact with MCT1. In the present study, it is hypothesized that the same amino acids within the transmembrane domain are used to interact with MCT4, but that no association exists with MCT2, which typically interacts with a different member of the IgSF subset. Therefore, the purpose of the present study was to assess the association between Basigin gene products and MCT4, and with MCT2. Recombinant proteins corresponding to the transmembrane domain of Basigin gene products were used in in vitro binding assays with endogenous MCT2 and MCT4 from mouse brain protein lysates. Contrary to the hypothesis, it was determined that the transmembrane domain of Basigin gene products binds to both MCT2 and MCT4 in vitro. Different amino acids within the transmembrane domain of Basigin gene products are used for each association and the pattern is different from that used in the association with MCT1. The data suggest that Basigin plays multiple roles in the nervous system

    Localization Using Convolutional Neural Networks

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    With the increased accessibility to powerful GPUs, ability to develop machine learning algorithms has increased significantly. Coupled with open source deep learning frameworks, average users are now able to experiment with convolutional neural networks (CNNs) to solve novel problems. This project sought to train a CNN capable of classifying between various locations within a building. A single continuous video was taken while standing at each desired location so that every class in the neural network was represented by a single video. Each location was given a number to be used for classification and the video was subsequently titled locX. These videos were converted to frames to train several well known CNNs using fine-tuning. Once the CNNs were trained, their performance on test sets of photos were observed

    Description of the PMAD DC test bed architecture and integration sequence

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    NASA-Lewis is responsible for the development, fabrication, and assembly of the electric power system (EPS) for the Space Station Freedom (SSF). The SSF power system is radically different from previous spacecraft power systems in both the size and complexity of the system. Unlike past spacecraft power system the SSF EPS will grow and be maintained on orbit and must be flexible to meet changing user power needs. The SSF power system is also unique in comparison with terrestrial power systems because it is dominated by power electronic converters which regulate and control the power. Although spacecraft historically have used power converters for regulation they typically involved only a single series regulating element. The SSF EPS involves multiple regulating elements, two or more in series, prior to the load. These unique system features required the construction of a testbed which would allow the development of spacecraft power system technology. A description is provided of the Power Management and Distribution (PMAD) DC Testbed which was assembled to support the design and early evaluation of the SSF EPS. A description of the integration process used in the assembly sequence is also given along with a description of the support facility

    Supercritical multicomponent solvent coal extraction

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    The yield of organic extract from the supercritical extraction of coal with larger diameter organic solvents such as toluene is increased by use of a minor amount of from 0.1 to 10% by weight of a second solvent such as methanol having a molecular diameter significantly smaller than the average pore diameter of the coal

    Leptogenesis from Soft Supersymmetry Breaking (Soft Leptogenesis)

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    Soft leptogenesis is a scenario in which the cosmic baryon asymmetry is produced from a lepton asymmetry generated in the decays of heavy sneutrinos (the partners of the singlet neutrinos of the seesaw) and where the relevant sources of CP violation are the complex phases of soft supersymmetry-breaking terms. We explain the motivations for soft leptogenesis, and review its basic ingredients: the different CP-violating contributions, the crucial role played by thermal corrections, and the enhancement of the efficiency from lepton flavour effects. We also discuss the high temperature regime T>107T > 10^7 GeV in which the cosmic baryon asymmetry originates from an initial asymmetry of an anomalous RR-charge, and soft leptogenesis reembodies in RR-genesis.Comment: References updated. Some minor corrections to match the published versio

    A Strong Impact of Genetic Background on Gut Microflora in Mice

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    Genetic background affects susceptibility to ileocolitis in mice deficient in two intracellular glutathione peroxidases, GPx1 and GPx2. The C57BL/6 (B6) GPx1/2 double-knockout (DKO) mice have mild ileocolitis, and 129S1/Sv (129) DKO mice have severe inflammation. We used diet to modulate ileocolitis; a casein-based defined diet with AIN76A micronutrients (AIN) attenuates inflammation compared to conventional LabDiets. Because luminal microbiota induce DKO ileocolitis, we assessed bacterial composition with automated ribosomal intergenic-spacer analysis (ARISA) on cecal DNA. We found that mouse strain had the strongest impact on the composition of microbiota than diet and GPx genotypes. In comparing AIN and LabDiet, DKO mice were more resistant to change than the non-DKO or WT mice. However, supplementing yeast and inulin to AIN diet greatly altered microflora profiles in the DKO mice. From 129 DKO strictly, we found overgrowth of Escherichia coli. We conclude that genetic background predisposes mice to colonization of potentially pathogenic E. coli
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