A Taste for Dim Sum: Analysing the Financial Diffusion in the New Offshore Renminbi Debt Securities

Periodically a major financial innovation creates a new product class that changes the financial landscape. Examples include junk bonds that enabled leveraged buyouts, securitization that stimulated off balance sheet growth in banks, and credit default swaps that offered pure trading in credit risk. Now new renminbi financial products are emerging as China opens its capital account, providing new opportunities for innovation in corporate finance that will promote financial stability and sustainable growth in China. This study illustrates the rapid growth in the use of these new products by Chinese and overseas firms. We use diffusion models to explore how participation in this market is influenced by greater depth and liquidity of the market, lower costs of issuance and greater expected appreciation of the renminbi against the US dollar. Understanding these offshore developments will help support smoother innovation in the onshore corporate bond market

Development of a nationwide network for technology transfer

The winter and spring of 1987 saw the cooperative nationwide network for technology transfer translated from concept to reality. The most obvious of the network relationships which were developed or which are anticipated are summarized. The objective was to help assure that every U.S. business which has the capacity to exploit, or the need to obtain new technology in any form, has access to the technology it needs or can use

First‐arrival traveltime sound speed inversion with a priori information

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134972/1/mp5955.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134972/2/mp5955_am.pd

Research Exchange - December 1, 2020 How to Navigate a Revise and Resubmit with Paul Pavlou and Wai Fong Boh

One of the most challenging aspects of publishing research is the revise and resubmit process. Join Paul Pavlou and Wai Fong Boh as they dive into the topics of engaging with the peer-review process with colleagues, gaining clarity from revision requests, creating workflow processes to address reviewer comments, and improving communication with editors. Paul A. Pavlou, a prominent researcher and expert on data analytics and digital business strategy, joined Bauer College as Dean and Cullen Distinguished Chair at the University of Houston in 2019. Pavlou previously served as Senior Associate Dean for Faculty Research, Doctoral Programs, and Strategic Initiatives at the Fox School of Business at Temple University, where he was also the Milton F. Stauffer Professor and Co-Director of the university-wide Data Science Institute. In his administrative role at the Fox School, Pavlou was responsible for overseeing all research activities and centers, including the development and mentoring of research faculty and Ph.D. students. During his tenure, five of the school’s disciplines were among the Top 10 in the nation in terms of research productivity. Pavlou initiated and implemented a strategic plan to enhance the school’s research visibility and showcase the broader impact of research on academia, industry, practice, the classroom, and public policy and society. Wai Fong Boh is Professor of Information Systems at Nanyang Technological University (NTU) in Singapore. She is currently the Deputy Dean of Nanyang Business School (NBS), Head of the Division of Information Technology and Operations Division, and Director of Information Management Research Centre at NBS. She received her PhD from the Tepper School of Business at the Carnegie Mellon University. Her research interests are in the areas of knowledge and innovation management and entrepreneurship. She has published in leading IS and management journals, including Management Science, MIS Quarterly, Academy of Management Journal, Organization Science, Journal of Management Information Systems, Journal of Association Information Systems, Research Policy, and Information & Organization. She has also won multiple awards, including an award for the Top Five IS Publications of the Year 2007. She is currently a Senior Editor of MIS Quarterly, and is currently on or has been previously on the editorial board of multiple journals, including Journal of Management Information Systems, Management Science, Information Systems Research, Organization Science, and Information & Organization

Development and Application of an Integrated Approach toward NASA Airspace Systems Research

The National Aeronautics and Space Administration's (NASA) Airspace Systems Program is contributing air traffic management research in support of the 2025 Next Generation Air Transportation System (NextGen). Contributions support research and development needs provided by the interagency Joint Planning and Development Office (JPDO). These needs generally call for integrated technical solutions that improve system-level performance and work effectively across multiple domains and planning time horizons. In response, the Airspace Systems Program is pursuing an integrated research approach and has adapted systems engineering best practices for application in a research environment. Systems engineering methods aim to enable researchers to methodically compare different technical approaches, consider system-level performance, and develop compatible solutions. Systems engineering activities are performed iteratively as the research matures. Products of this approach include a demand and needs analysis, system-level descriptions focusing on NASA research contributions, system assessment and design studies, and common systemlevel metrics, scenarios, and assumptions. Results from the first systems engineering iteration include a preliminary demand and needs analysis; a functional modeling tool; and initial system-level metrics, scenario characteristics, and assumptions. Demand and needs analysis results suggest that several advanced concepts can mitigate demand/capacity imbalances for NextGen, but fall short of enabling three-times current-day capacity at the nation s busiest airports and airspace. Current activities are focusing on standardizing metrics, scenarios, and assumptions, conducting system-level performance assessments of integrated research solutions, and exploring key system design interfaces

p66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis.

p66Shc, a 66 kDa proto-oncogene Src homologous-collagen homologue (Shc) adaptor protein, is classically known in mediating receptor tyrosine kinase signaling and recently identified as a sensor to oxidative stress-induced apoptosis and as a longevity protein in mammals. The expression of p66Shc is decreased in mice and increased in human fibroblasts upon aging and in aging-related diseases, including prostate cancer. p66Shc protein level correlates with the proliferation of several carcinoma cells and can be regulated by steroid hormones. Recent advances point that p66Shc protein plays a role in mediating cross-talk between steroid hormones and redox signals by serving as a common convergence point in signaling pathways on cell proliferation and apoptosis. This article first reviews the unique function of p66Shc protein in regulating oxidative stress-induced apoptosis. Subsequently, we discuss its novel role in androgen-regulated prostate cancer cell proliferation and metastasis and the mechanism by which it mediates androgen action via the redox signaling pathway. The data together indicate that p66Shc might be a useful biomarker for the prognosis of prostate cancer and serve as an effective target for its cancer treatment