Folate supplementation and coronary heart disease risk in subjects with type-2 diabetes

The primary objective of this study was to evaluate the risk of coronary heart disease (CHD) correlated to total homocysteine (tHcy) levels among Hispanics (25.6%) and non-Hispanic whites (74.4%) with type-2 diabetes. The charts of 39 subjects with type-2 diabetes were selected from one physician’s caseload for a convenience sample. This endocrinologist has been supplementing his patients with 1-3 mg of folic acid daily if their tHcy levels were \u3e 13 pmol/L. We found a significant difference (p \u3c .001) between tHcy levels at baseline, follow-up I and follow-up II with a mean total reduction of 4 pmol/L. The results indicated that tHcy levels could be reduced by 1-2 mg folic acid daily in 2-8 months in subjects with type-2 diabetes. The recommendation generated from this study’s findings is that a folic acid supplement be consumed as part of a long-term management regimen for type-2 diabetics

Manganese 5,10,15,20-Tetra(N-ethyl-3-carbazolyl) Porphyrin

Manganese complex of 5,10,15,20-tetra(N-ethyl-3-carbazolyl) porphyrin was synthesized and characterized by electronic absorption spectrophotometry and cyclic voltammetry. The spectral data were in agreement with the proposed structure. The manganese complex exhibited a shift in the Soret band in comparison to the non-metallated porphyrin and the extinction coefficient for the Soret band was on the order of 105 cm-1M-1. Trends observed in the oxidation and reduction potentials were consistent with the nature of the porphyrin. That is, the electron donating group in 5,10,15,20-tetra(N-ethyl-3-carbazolyl) porphyrin enhances oxidation and inhibits reduction

Are Religious Teens Nice Kids? Faith and Congeniality among American Adolescents

One body of extant research has documented the social contours and positive effects of teen religiosity, while another has explored the religious sources of social congeniality (“niceness„) among adult Americans. This study integrates these parallel bodies of scholarship by examining the religious bases of niceness among American teens. Using post-hoc interviewer ratings from wave 1 of the National Longitudinal Study of Adolescent Health (Add Health), we examine the degree to which religious teens are perceived more positively than their nonreligious peers. Associations linked to six dimensions of teen religiosity are considered. Select facets of teen religiosity are associated with more positive interviewer ratings, particularly for interpersonal warmth, thereby providing modest support for hypothesized patterns. Findings are interpreted in light of current theories of religious involvement, interpersonal dispositions, and social competencies

Synthesis and characterization of 5,10,15,20-tetra (N-ethyl-3-carbazoyl) porphyrin

1658-1665The newly prepared 5,10,15,20-tetra(N-ethyl-3-carbazoyl) porphyrin is characterized by ¹H NMR, FAB-HRMS, UV-visible spectrophotometry, fluorescence spectrometry, and electrochemistry. The porphyrin display an extinction coefficient of 2.8 × 10⁵ cm⁻¹M⁻¹ for the Soret band at 433 nm. Three Q bands have been also observed at 523, 563, and 655 nm with corresponding extinction coefficients given as 1.3 × 10⁴, 1.1 × 10⁴, and 5.6 × 10³ cm⁻¹M⁻¹. Excitation at 433 nm gives an emission line at 662 nm. The quantum yield has been determined to be 0.09. Cyclic voltammetry has been used to determine the oxidation and reduction potentials of the new porphyrin. Two quasi-reversible one-electron oxidations have been observed at 0.862 and 1.010 V and a quasi-reversible reduction of the chromophore has been observed at -1.186 V versus the standard calomel electrode with tetrabutylammonium tetrafluoroborate as the supporting electrolyte. Carbazole is an electron donating group covalently attached to the porphyrin in the meso positions. Trends observed in the oxidation and reduction potentials are consistent with the nature of the porphyrin. That is, the electron donating group in 5,10,15,20-tetra(N-ethyl-3-carbazoyl) porphyrin enhances oxidation and inhibits reduction