Разработка осветительной установки молочной фермы с использованием автоматической системы управления освещением

В ходе выполнения ВКР решалось несколько основных задач: улучшение светового климата внутри помещений для содержания крупного рогатого скота и, как следствие, увеличение производительности молочных коров; повышение эффективности системы искусственного освещения на молочных фермах с использованием энергосберегающих осветительных средств (реконструкция осветительной установки и внедрение автоматической системы управления освещением по протоколу DALI), позволяющих снизить расход электрической энергии на процесс освещения.During the implementation of the graduation work, several main tasks were solved: improving the light climate within the premises for cattle and, as a consequence, increasing the productivity of dairy cows; increasing the efficiency of the artificial lighting system on dairy farms using energy-saving lighting (reconstruction of the lighting system and the introduction of an automatic lighting control system using the DALI protocol), which allow to reduce the electric energy consumption for the lighting process

Mesopelagic prokaryotic bulk and single-cell heterotrophic activity and community composition in the NW Africa–Canary Islands coastal-transition zone

8 pages, 3 figures, 2 tablesMesopelagic prokaryotic communities have often been assumed to be relatively inactive in comparison to those from epipelagic waters, and therefore unresponsive to the presence of nearby upwelled waters. We have studied the zonal (shelf-ocean), latitudinal, and depth (epipelagic–mesopelagic) variability of microbial assemblages in the NW Africa–Canary Islands coastal-transition zone (CTZ). Vertical profiles of bacterial bulk and single-cell activity through the epi- and mesopelagic waters were combined with point measurements of bacterial respiration, leucine-to-carbon conversion factors and leucine-to-thymidine incorporation ratios. The overall picture that emerges from our study is that prokaryotes in the mesopelagic zone of this area are less abundant than in the epipelagic but have comparable levels of activity. The relationship between prokaryotes and heterotrophic nanoflagellates, their main predators, remains constant throughout the water column, further contradicting the assumption that deep ocean bacterial communities are mostly inactive. Both bulk and single-cell activity showed clear differences between stations, with higher mesopelagic activities closer to the shelf or affected by upwelling features. We also tested whether differences in microbial function between stations could be related to differences in bacterial community structure, and conclude that bacterial communities are very similar at similar depths in the deep ocean, even if the stations present order-of-magnitude differences in bacterial functionThis work was supported by Grants COCA (REN2000 1471-CO2-O1-MAR), RODA (CTM 2004-06842-C03/MAR) and MODIVUS (CTM2005-04795/MAR), and is a contribution to EU Networks of Excellence EUROCEANS and MARBEFPeer reviewe

Theranostic USPIO-loaded microbubbles for mediating and monitoring blood-brain barrier permeation

Efficient and safe drug delivery across the blood-brain barrier (BBB) remains one of the major challenges of biomedical and (nano-) pharmaceutical research. Here, it is demonstrated that poly(butyl cyanoacrylate)-based microbubbles (MB), carrying ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles within their shell, can be used to mediate and monitor BBB permeation. Upon exposure to transcranial ultrasound pulses, USPIO-MB are destroyed, resulting in acoustic forces inducing vessel permeability. At the same time, USPIO are released from the MB shell, they extravasate across the permeabilized BBB and they accumulate in extravascular brain tissue, thereby providing non-invasive R2 ∗-based magnetic resonance imaging information on the extent of BBB opening. Quantitative changes in R2 ∗ relaxometry are in good agreement with 2D and 3D microscopy results on the extravascular deposition of the macromolecular model drug fl uorescein isothiocyanate (FITC)-dextran into the brain. Such theranostic materials and methods are considered to be useful for mediating and monitoring drug delivery across the BBB and for enabling safe and efficient treatment of CNS disorders