18 research outputs found
Fusion of the -Vertex Operators and its Application to Solvable Vertex Models
We diagonalize the transfer matrix of the inhomogeneous vertex models of the
6-vertex type in the anti-ferroelectric regime intoducing new types of q-vertex
operators. The special cases of those models were used to diagonalize the s-d
exchange model\cite{W,A,FW1}. New vertex operators are constructed from the
level one vertex operators by the fusion procedure and have the description by
bosons. In order to clarify the particle structure we estabish new isomorphisms
of crystals. The results are very simple and figure out representation
theoretically the ground state degenerations.Comment: 35 page
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
E77 Role of alpha-adrenergic blockers in enhancing clearance of stone fragments after ESWL of renal calculi
Construction and performance of the barrel electromagnetic calorimeter for the GlueX experiment
The barrel calorimeter is part of the new spectrometer installed in Hall D at Jefferson Lab for the GlueX experiment. The calorimeter was installed in 2013, commissioned in 2014 and has been operating routinely since early 2015. The detector configuration, associated Monte Carlo simulations, calibration and operational performance are described herein. The calorimeter records the time and energy deposited by charged and neutral particles created by a multi-GeV photon beam. It is constructed as a lead and scintillating-fiber calorimeter and read out with 3840 large-area silicon photomultiplier arrays. Particles impinge on the detector over a wide range of angles, from normal incidence at 90 degrees down to 11.5 degrees, which defines a geometry that is fairly unique among calorimeters. The response of the calorimeter has been measured during a running experiment and performs as expected for electromagnetic showers below 2.5 GeV. We characterize the performance of the BCAL using the energy resolution integrated over typical angular distributions for and η production of =5.2\% 3.6\% and a timing resolution of σ\,=\,150\,ps at 1\,GeV
Measurement of the photon beam asymmetry in γ - p→K+ ς0 at Eγ=8.5 GeV
We report measurements of the photon beam asymmetry ς for the reaction γ - p→K+ς0(1193) using the GlueX spectrometer in Hall D at Jefferson Lab. Data were collected by using a linearly polarized photon beam in the energy range of 8.2-8.8 GeV incident on a liquid hydrogen target. The beam asymmetry ς was measured as a function of the Mandelstam variable t, and a single value of ς was extracted for events produced in the u channel. These are the first exclusive measurements of the photon beam asymmetry ς for the reaction in this energy range. For the t channel, the measured beam asymmetry is close to unity over the t range studied, -t=(0.1-1.4)(GeV/c)2, with an average value of ς=1.00±0.05. This agrees with theoretical models that describe the reaction via the natural-parity exchange of the K∗(892) Regge trajectory. A value of ς=0.41±0.09 is obtained for the u channel integrated up to -u=2.0 (GeV/c)2. © 2020 American Physical Society
Measurement of beam asymmetry for π- Δ++ photoproduction on the proton at Eγ=8.5 GeV
We report a measurement of the π- photoproduction beam asymmetry for the reaction γp→π-Δ++ using data from the GlueX experiment in the photon beam energy range 8.2-8.8 GeV. The asymmetry ς is measured as a function of four-momentum transfer t to the Δ++ and compared to phenomenological models. We find that ς varies as a function of t: negative at smaller values and positive at higher values of |t|. The reaction can be described theoretically by t-channel particle exchange requiring pseudoscalar, vector, and tensor intermediaries. In particular, this reaction requires charge exchange, allowing us to probe pion exchange and the significance of higher-order corrections to one-pion exchange at low momentum transfer. Constraining production mechanisms of conventional mesons may aid in the search for and study of unconventional mesons. This is the first measurement of the process at this energy. © 2021 American Physical Society
First Measurement of Near-Threshold J /ψ Exclusive Photoproduction off the Proton
We report on the measurement of the γp→J/ψp cross section from Eγ=11.8 GeV down to the threshold at 8.2 GeV using a tagged photon beam with the GlueX experiment. We find that the total cross section falls toward the threshold less steeply than expected from two-gluon exchange models. The differential cross section dσ/dt has an exponential slope of 1.67±0.39 GeV-2 at 10.7 GeV average energy. The LHCb pentaquark candidates Pc+ can be produced in the s channel of this reaction. We see no evidence for them and set model-dependent upper limits on their branching fractions B(Pc+→J/ψp) and cross sections σ(γp→Pc+)×B(Pc+→J/ψp). © 2019 American Physical Society