Metrology For Advanced Manufacturing – The Networking Project AdvManuNet

Advanced Manufacturing is a branch of manufacturing that is considered an important driver for future economic and societal progress. The European Commission (EC) has identified Advanced Manufacturing as one of six Key Enabling Technologies (KETs) with applications across multiple industrial sectors. The networking project JNP19Net01 AdvManuNet funded by EURAMET for four years starting in June 2020 aims to accelerate the process of establishing a European Metrology Network (EMN) to strengthen Europe’s position in Advanced Manufacturing. The consortium to deliver this project comprises National Metrological Institutes (PTB, NPL, INRIM, RISE, CMI, METAS, TUBITAK, GUM), Designated Institutes (BAM), University partners (Politecnico di Torino) and the European Society for Precision Engineering and Nanotechnology (euspen) from across Europe

New European Metrology Network for advanced manufacturing

Advanced manufacturing has been identified as one of the key enabling technologies with applications in multiple industries. The growing importance of advanced manufacturing is reflected by an increased number of publications on this topic in recent years. Advanced manufacturing requires new and enhanced metrology methods to assure the quality of manufacturing processes and the resulting products. However, a high-level coordination of the metrology community is currently absent in this field and consequently this limits the impact of metrology developments on advanced manufacturing. In this article we introduce the new European Metrology Network (EMN) for Advanced Manufacturing within EURAMET, the European Association of National Metrology Institutes (NMIs). The EMN is intended to be operated sustainably by NMIs and Designated Institutes in close cooperation with stakeholders interested in advanced manufacturing. The objectives of the EMN are to set up a permanent stakeholder dialogue, to develop a Strategic Research Agenda for the metrology input required for advanced manufacturing technologies, to create and maintain a knowledge sharing programme and to implement a web-based service desk for stakeholders. The EMN development is supported by a Joint Network Project within the European Metrology Programme for Innovation and Research

Pregnancy Does Not Affect HIV Incidence Test Results Obtained Using the BED Capture Enzyme Immunoassay or an Antibody Avidity Assay

Accurate incidence estimates are needed for surveillance of the HIV epidemic. HIV surveillance occurs at maternal-child health clinics, but it is not known if pregnancy affects HIV incidence testing.We used the BED capture immunoassay (BED) and an antibody avidity assay to test longitudinal samples from 51 HIV-infected Ugandan women infected with subtype A, C, D and intersubtype recombinant HIV who were enrolled in the HIVNET 012 trial (37 baseline samples collected near the time of delivery and 135 follow-up samples collected 3, 4 or 5 years later). Nineteen of 51 women were also pregnant at the time of one or more of the follow-up visits. The BED assay was performed according to the manufacturer's instructions. The avidity assay was performed using a Genetic Systems HIV-1/HIV-2 + O EIA using 0.1M diethylamine as the chaotropic agent.During the HIVNET 012 follow-up study, there was no difference in normalized optical density values (OD-n) obtained with the BED assay or in the avidity test results (%) when women were pregnant (n = 20 results) compared to those obtained when women were not pregnant (n = 115; for BED: p = 0.9, generalized estimating equations model; for avidity: p = 0.7, Wilcoxon rank sum). In addition, BED and avidity results were almost exactly the same in longitudinal samples from the 18 women who were pregnant at only one study visit during the follow-up study (p = 0.6, paired t-test).These results from 51 Ugandan women suggest that any changes in the antibody response to HIV infection that occur during pregnancy are not sufficient to alter results obtained with the BED and avidity assays. Confirmation with larger studies and with other HIV subtypes is needed

Projects management cost factors for the optimization of forestry enterprises production structure

The management factors which influence on the project’s cost for the optimization of forestry enterprises production structure have been considered in the article. The key aspects of projects costs have been determined for a management which set them hierarchical subordination

Визначення узагальнених критеріїв оптимальності вибору об’єктів укриття цивільних осіб від ударів балістичними (крилатими) ракетами та БПЛА-камікадзе в урбанізованих територіях

The object of the study is the planning of the selection of civilian shelter from attacks by ballistic (cruise) missiles and kamikaze drones in urbanized areas. A generalized model for assessing the choice of civilian shelter facilities has been developed by applying linear forms of factor linkage in combination with a general-ized optimality criterion in the form of a linear combination of local criteria. The multivariate regression analysis method was chosen to study the correlation between the generalized criterion and the observed feature. A generalized criterion for the op-timal choice of civilian shelter facilities from attacks by ballistic (cruise) missiles and kamikaze drones in urbanized areas is calculated in the form of regression coef-ficients. The criterion can facilitate a simplified determination of the generalized in-dicator of a linear model for planning the protection of civilians in cities outside the area of hostilities. The initial data is a set of physical (technical) states of shelters with a list of values and features sufficient to assess their resistance to high dynamic loadsОб’єктом дослідження є планування вибору засобів укриття цивільного населення від атак балістичними (крилатими) ракетами та ударними безпілотними літальними апаратами (БпЛА) в урбанізованих районах. Розроблено узагальнену модель оцінювання вибору засобів укриття цивільного населення шляхом застосування лінійних форм зв’язку факторів у поєднанні з узагальненим критерієм оптимальності у вигляді лінійної комбінації локальних критеріїв. Як метод дослідження кореляції між узагальненим критерієм та спостережною ознакою обрано метод багатовимірного регресійного аналізу. Розраховано узагальнений критерій оптимальності вибору засобів укриття цивільного населення від атак балістичними (крилатими) ракетами та ударними БпЛА в урбанізованих районах у вигляді коефіцієнтів формування регресії. Критерій здатенсприяти спрощеному визначенню узагальненого показника лінійної моделі планування захисту мирних громадян у містах поза межами бойових дій. Вихідними даними є набір фізичних (технічних) станів укриттів з переліком величин і ознак, достатніх для оцінювання їх стійкості до високих динамічних навантажень

European Metrology Network for Advanced Manufacturing

The progress of Advanced Manufacturing, which has been identified by the European Commission as a Key Enabling Technology (KET) for future economic and societal progress is strongly reliant on the development of metrology capabilities. EURAMET, the association of metrology institutes in Europe, has established metrology research programs to address the metrology requirements across a spectrum of different thematic areas. In order to leverage the benefits of these developments on the wider industrial landscape, a high-level coordination of the metrology community supporting the Advanced Manufacturing landscape is required. This coordination is aimed to be achieved by the establishment of European Metrology Networks (EMNs), which are intended by EURAMET to provide a sustainable structure for stakeholder engagement and support. The joint networking project 19NET01 AdvManuNet funded by EMPIR for 4 years, started in June 2020 and aims to accelerate the process of establishing an EMN to strengthen Europe’s position in Advanced Manufacturing. The AdvManuNet project aims to support the establishment of an EMN on Advanced Manufacturing via the following specific aims: 1. Creation of a single hub for stakeholder engagement across the landscape of various industrial sectors including relevant societies and standardization bodies. 2. Development of a Strategic Research Agenda (SRA) and roadmaps for Advanced Manufacturing metrology based on the stakeholder engagement activities, considering current gaps in metrological capabilities existing networks and roadmaps. 3. Establish a knowledge-sharing program for Advanced Manufacturing stakeholders, promoting the dissemination and exploitation of the results of the project, including those from previous EU funded research projects. 4. Development of a sustainable web-based platform and service desk for Advanced Manufacturing stakeholders to allow for easy access to European metrology capabilities and support the wider advanced manufacturing community with metrology-based requirements. 5. Develop a plan for a coordinated and sustainable European metrology infrastructure for Advanced Manufacturing via a European Metrology Network. The project concept followed by the scope and definition of Advanced Manufacturing will be described. The analysis of the current capability of metrology for Advanced Manufacturing and the preliminary concepts for the strategic research agenda will be presented with a focus on dimensional metrology. Acknowledgement The project JNP 19NET01 AdvManuNet has received funding from the EMPIR programme co-financed by the Participating States and from the European Union’s Horizon 2020 research and innovation programme

Determining the Components of the Structural-automatic Model of Firing A Single Target in Armor Protection with Fragmentation-beam Projectiles of Directed Action in A Series of Three Shots Based on the Reference Graph of States

The problem of determining the components of the structural-automatic model is solved by creating a graph of states and transitions. The purpose of the process is to form a formalized expression of the object of study in the form of a structural-machine model of the process of firing a mobile armored vehicle with a series of three shots with fragmentation-beam projectiles of directional action. This model can be further practically implemented during the development of the latest samples of fire resistance in order to reduce errors at the stage of system design. This approach reduces the cost of design and production of prototypes by up to 25 %. This paper considers the process involving interrelated elements of the components of a system while accounting for all possible variants of its behavior from the moment of detection to the failure of a single target in armor protection to perform tasks as intended. The execution of a fire task is considered as a set of certain procedures characterized by the average value of their duration. The explosive destruction of the hull of each fragmentation-beam projectile is characterized by the self-propagation of the reaction of explosive transformations based on tabular data on an armored combat vehicle. Appropriate procedures (phases) of firing a single target in armor protection are advisable to formalize to create preconditions for obtaining the value of a statistical indicator of the effectiveness of causing damage to the target and to study further alternative options for this process. For the proposed structural-automatic model of the process of firing a single target in armor protection with a series of fragmentation-beam projectiles of directional action, validation and verification were carried out, which demonstrated the convergence of the results that exceeded 60 %. The use of the structural-automatic model's components proposed in this work increases the probability of performing a fire task for the first shot from 0.23 to 0.88, for the second – from 0.35 to 0.95, for the third – from 0.45 to 0.9