1 research outputs found
Renal Complications Due to SARS-CoV-2 Infection in Pediatric Population
Background and Aim: COVID-19 pandemic originated in Wuhan City, China, in 2019.The disease spectrum ranges from asymptomatic to severe respiratory failure leadingto death. Although in a lower percentage, pediatric patients also have complications,not only pulmonary but also systemic, affecting other organs. This article aims to studythe renal involvement of pediatric patients infected by the Severe Acute RespiratorySyndrome Coronavirus 2 (SARS-CoV-2).Methods: We designed a retrospective observational cohort study of patientshospitalized in the emergency department and intensive care unit of a tertiary medicalfacility hospital Infantil de MĂ©xico Federico Gomez in Mexico City, from March 1,2020, to May 16, 2021. The inclusion criteria included patients younger than 18 yearswho had a positive Reverse Transcription-Polymerase Chain Reaction (RT-PCR) test ora positive rapid antigen test of nasopharyngeal sample for SARS-CoV-2 at admission.Results: We included 165 patients, of whom 29(17.6%) patients developed renalcomplications during hospitalization. In these patients, 12(41.3%) patients developedproteinuria, 10(34.5%) developed any type of Acute Kidney Injury (AKI), i.e., AcuteKidney Injury Network (AKIN-1) in 26.6%, AKIN-2 in 40% and AKIN-3 in 33.3%.Also, 5(17.2%) patients had arterial hypertension, 2(6.9%) required renal replacementtherapy, 4(13.8%) had hematuria. Only 1(3.4%) patient had developed rapidlyprogressive glomerulonephritis.Conclusion: COVID-19 infection within its spectrum can cause kidney disease; themost common complications are proteinuria and AKI. Older age and admission to theintensive care unit are risk factors for kidney damage