3,422 research outputs found

    Improvement of oral reports through the students' use of audio-visual aids

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    Author misnumbered thesis. Please note that there are TWO page 108s, but the continuity is the same. Thesis (Ed.M.)--Boston Universit

    Stability of Hematological Parameters in Woodland Caribou (Rangifer tarandus caribou) Blood Stored at 4°C

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    Eighteen free-ranging female woodland caribou were captured in northern Alberta in January and February 1993. Blood was collected into ethylenediaminetetraacetate (EDTA) tubes which were packaged in coolers containing ice packs, and transported to the laboratory where they arrived within 48 hrs of collection. Complete blood counts (CBC) were performed on five consecutive days to assess the stability of hematological parameters. Average values of hematocrit (HCT), mean cell hemoglobin (MCH), mean cell volume (MCV), red cell distribution width (P-J3W), white blood cell count (WBC), and red blood cell count (RJ3C) remained stable with no statistically significant changes occurring during 5 days of post-collection storage at 4°C. Mean PvBC values exhibited significant differences (p<0.05) between geographic locations. Mean platelet volume (MPV) increased significantly (p<0.001) with storage time, while platelet (PLT) values decreased (p<0.001) over time and were significantly different (p<0.01) between locations. For optimal hematological results, it is recommended that sample analysis be performed within 24 hours of blood collection; however, if caribou blood samples are properly stored at 4°C, useful information may be obtained from stable parameters up to 5 days following collection

    Microfactory – Blend – Compression - Performance test

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    Aims and objectives - API’s with acicular habits are commonplace and present processing and handling challenges due to poor flow. This is traditionally addressed by wet granulation processes during formulation. Currently continuous direct compression (CDC) is gaining favour as a simplified formulation and dose formation process. However, poor flow properties limit CDC. This work aims to enable CDC by spherical agglomeration in the primary process and develop underpinning modelling approaches to allow formulations to be explored in-silico (i.e. digital twin) - Here at CMAC an integrated crystalisation-spherical agglomeration-drying-blending-compression process is being developed (microfactory) to be used to parameterise and develop modelling tools on the g-formulate package - This work presents some of the activities on the compression component to parameterise and develop a suitable model to enable the process to be explored (i.e. digital twin

    Zinc fertilization increases productivity and grain nutritional quality of cowpea (Vigna unguiculata [L.] Walp.) under integrated soil fertility management

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    Cowpea (Vigna unguiculata [L.] Walp.) is an important but under-studied grain legume which can potentially contribute to improved dietary zinc (Zn) intake in sub-Saharan Africa. In this study, surveys were conducted on smallholder farms in Zimbabwe during 2014/15 to determine the influence of diverse soil fertility management options on cowpea grain productivity and nutrition quality. Guided by the surveys, field experiments were conducted to investigate the influence of Zn fertilizer on the productivity and quality of cowpea under integrated soil fertility management (ISFM). Experiments were conducted on two soil-types, namely, sandy (6% clay) and red clay (57% clay) in 2014/15 and 2015/16 where cowpea was grown in rotation with staple maize (Zea mays L.) and fertilized with combinations of Zn, nitrogen (N), phosphorus (P) and two organic nutrient resources, cattle manure and woodland leaf litter. Cowpea grain yields on surveyed farms ranged from 0.3 to 0.9 t ha−1, with grain Zn concentration ranging from 23.9 to 30.1 mg kg−1. The highest grain Zn concentration was on fields where organic nutrient resources were applied in combination with mineral N and P fertilizers. Within the field experiments, mean grain yields of cowpea increased by between 12 and 18% on both soil types when Zn fertilizer was applied, from a baseline of 1.6 and 1.1 t ha−1 on red clay and sandy soils, respectively. When Zn fertilizer was co-applied with organic nutrient resources, grain Zn concentrations of cowpea reached 42.1 mg kg−1 (red clay) and 44.7 mg kg−1 (sandy) against grain Zn concentrations of 35.9 mg kg−1 and 31.1 mg kg−1 measured in cowpea grown with no Zn fertilizer on red clay and sandy soils, respectively. Agronomic biofortification of legumes is feasible and has the potential to contribute significantly towards increasing dietary Zn intake by humans. A greater increase in grain Zn of cowpea grown on sandy than red clay soils under Zn fertilization illustrates the influence of soil type on Zn uptake, which should be explored further in agronomic biofortification programs

    Fighting Ebola with novel spore decontamination technologies for the military

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    AbstractRecently, global public health organizations such as Doctors without Borders (MSF), the World Health Organization (WHO), Public Health Canada, National Institutes of Health (NIH), and the U.S. government developed and deployed Field Decontamination Kits (FDKs), a novel, lightweight, compact, reusable decontamination technology to sterilize Ebola-contaminated medical devices at remote clinical sites lacking infra-structure in crisis-stricken regions of West Africa (medical waste materials are placed in bags and burned). The basis for effectuating sterilization with FDKs is chlorine dioxide (ClO2) produced from a patented invention developed by researchers at the US Army – Natick Soldier RD&E Center (NSRDEC) and commercialized as a dry mixed-chemical for bacterial spore decontamination. In fact, the NSRDEC research scientists developed an ensemble of ClO2 technologies designed for different applications in decontaminating fresh produce; food contact and handling surfaces; personal protective equipment; textiles used in clothing, uniforms, tents, and shelters; graywater recycling; airplanes; surgical instruments; and hard surfaces in latrines, laundries, and deployable medical facilities. These examples demonstrate the far-reaching impact, adaptability, and versatility of these innovative technologies. We present herein the unique attributes of NSRDEC’s novel decontamination technologies and a Case Study of the development of FDKs that were deployed in West Africa by international public health organizations to sterilize Ebola-contaminated medical equipment. FDKs use bacterial spores as indicators of sterility. We review the properties and structures of spores and the mechanisms of bacterial spore inactivation by ClO2. We also review mechanisms of bacterial spore inactivation by novel, emerging, and established nonthermal technologies for food preservation, such as high pressure processing, irradiation, cold plasma, and chemical sanitizers, using an array of
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