4,259 research outputs found
Investigation of foamed metals for application on space capsules annual report, 29 jun. 1963 - 15 aug. 1964
Foamed metal development for space capsules - brazing, variable density beam, thermal testing, mechanical tests, and machinin
Genetic variation of metabolite and hormone concentration in UK Holstein-Friesian calves and the genetic relationship with economically important traits
Notorious places: image, reputation, stigma: the role of newspapers in area reputations for social housing estates
This paper reviews work in several disciplines to distinguish between image, reputation and stigma. It also shows that there has been little research on the process by which area reputations are established and sustained through transmission processes. This paper reports on research into the portrayal of two social housing estates in the printed media over an extended period of time (14 years). It was found that negative and mixed coverage of the estates dominated, with the amount of positive coverage being very small. By examining the way in which dominant themes were used by newspapers in respect of each estate, questions are raised about the mode of operation of the press and the communities' collective right to challenge this. By identifying the way regeneration stories are covered and the nature of the content of positive stories, lessons are drawn for programmes of area transformation. The need for social regeneration activities is identified as an important ingredient for changing deprived-area reputations
16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice
Acknowledgements The authors acknowledge the assistance of Grietje Holtrop (RINH-BioSS) with the statistical analysis of the data and the Wellcome Trust Sanger Instituteâs 454 pyrosequencing team for generating 16S rRNA gene data. AWW, PS and JP received core funding support from the Wellcome Trust [grant number 098051]. AWW, JCM, HJF and KPS are funded by the Scottish Government (SG-RESAS).Peer reviewedPublisher PD
Density waves theory of the capsid structure of small icosahedral viruses
We apply Landau theory of crystallization to explain and to classify the
capsid structures of small viruses with spherical topology and icosahedral
symmetry. We develop an explicit method which predicts the positions of centers
of mass for the proteins constituting viral capsid shell. Corresponding density
distribution function which generates the positions has universal form without
any fitting parameter. The theory describes in a uniform way both the
structures satisfying the well-known Caspar and Klug geometrical model for
capsid construction and those violating it. The quasiequivalence of protein
environments in viral capsid and peculiarities of the assembly thermodynamics
are also discussed.Comment: 8 pages, 3 figur
Manufacturing of 100mm diameter GaSb substrates for advanced space based applications
Engineered substrates such as large diameter (100mm) GaSb wafers need to be ready years in advance of any major shift in DoD and commercial technology, and typically before much of the rest of the materials and equipment for fabricating next generation devices. Antimony based III-V semiconductors are of significant interest for advanced applications in optoelectronics, high speed transistors, microwave devices, and photovoltaics. GaSb demand is increasing due to its lattice parameter matching of various ternary and quaternary III-V compounds, as their bandgaps can be engineered to cover a wide spectral range. For these stealth and spaced based applications, larger format IRFPAs benefit clearly from next generation starting substrates. In this study, we have manufactured and tested 100mm GaSb substrates. This paper describes the characterization process that provides the best possible GaSb material for advanced IRFPA and SLS epi growth. The analysis of substrate by AFM surface roughness, particles, haze, GaSb oxide character and desorption using XPS, flatness measurements, and SLS based epitaxy quality are shown. By implementing subtle changes in our substrate processing, we show that a Sb-oxide rich surface is routinely provided for rapid desorption. Post-MBE CBIRD structures on the 100mm ULD GaSb were examined and reveals a high intensity, 6.6nm periodicity, low (15.48 arcsec) FWHM peak distribution that suggests low surface strain and excellent lattice matching. The Ra for GaSb is a consistent ~0.2-4nm, with average batch wafer warp of ~4 Îźm to provide a clean, flat GaSb template critical for next generation epi growth
The effect of in vitro fermentation of oats (Avena sativa) and barley (Hordeum vulgare) on the faecal gut microbiota
Basal-Plane Nonlinear Susceptibility: A Direct Probe of the Single-Ion Physics in URu2Si2
The microscopic nature of the hidden order state in URu2Si2 is dependent on
the low-energy configurations of the uranium ions, and there is currently no
consensus on whether it is predominantly 5f^2 or 5f^3. Here we show that
measurement of the basal-plane nonlinear susceptibility can resolve this issue;
its sign at low-temperatures is a distinguishing factor. We calculate the
linear and nonlinear susceptibilities for specific 5f^2 and 5f^3 crystal-field
schemes that are consistent with current experiment. Because of its dual
magnetic and orbital character, a \Gamma_5 magnetic non-Kramers doublet
ground-state of the U ion can be identified by where we have determined the constant of proportionality for
URu2Si2.Comment: 7 pages, 4 figure
Aseptic meningitis in a patient taking etanercept for rheumatoid arthritis: a case report
Background \ud
We report a case of a 53 year old lady recently commenced on etanercept, an anti-TNF (tumour necrosis factor) therapy for rheumatoid arthritis presenting with \ud
confusion, pyrexia and an erythematous rash. \ud
\ud
Case presentation \ud
A lumbar puncture was highly suggestive of bacterial meningitis, but CSF cultures produced no growth, and polymerase chain reactions (PCR) for all previously reported bacterial, fungal and viral causes of meningitis were negative. \ud
\ud
Conclusions \ud
This case report describes aseptic meningitis as a previously unreported complication of etanercept therapy, and serves as a reminder of the rare but potentially lifethreatening risk of serious infections in patients taking anti-TNF therapy for a variety of conditions
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