SPECIFIC BEHAVIOUR OF THE BLOOD SEDIMENTATION PROCESSES EXAMINED BY THE ELECTROCHEMICAL IMPEDANCE MICROSENSOR

Electrochemical impedance microsensor for the fast monitoring of the blood sedimentation has been developed. Planar microsensor consisted of the interdigital array of electrodes (IDAE - finger/gap widths of different values from 5/5 μm to 400/400 μm) based on Au or Pt thin films sputtered on Si/SiO2 or ceramic alumina substrates. IDAE microsensor allows time measurements of electrical impedance changes - impedance rates - (at frequencies of order 0.1 kHz and 10 kHz) of small blood drop applied on it. The determination of the impedance rate during sedimentation and the impedance spectrometry at a low-frequency range of order of 1 kHz seems to be very helpful for a quick diagnostics of the health state. In the IDAE microsensor erythrocyte aggregation/rapid settling/packing periods associated with dryperiod are overlapping due to the planar arrangement of dimensions in order of 1-100 μm. The time monitoring of the blood sedimentation (in the range of 10-900 seconds) by the impedance method can distinguish between healthy and cancer state of blood and could serve for the simple long-term diagnostics after the surgical operation or as a screening procedure for early diagnoses

GOLD NANOSTRUCTURES SPUTTERED ON ZINC OXIDE THIN FILM AND CORNING GLASS SUBSTRATES

Forming of Au nanostructures on Corning glass substrates and transparent conductive oxide ZnO:Al thin films by the RF diode sequential sputtering is presented. The morphology of Au structures was analysed by scanning electron microscopy (SEM) with the free ImageJ software, the optical properties were evaluated by UV-Vis spectrometry and micro-Raman spectroscopy. The sputtering power density (deposition rate) and nominal Au thickness caused changes in the sizes (10 – 1000 nm2) and nearest neighbour NN distances (4 – 40 nm) of Au nanostructures. The morphology of nanostructures exhibited the LogNormal distribution of the size of nanostructures. The lowest sputtering power density/deposition rate (9 mW/mm2/0.12 nm s–1) was optimal to get both the high optical transparency and a superior activity surface-enhanced Raman scattering of 11-mercaptoundecanoic acid adsorbed on the Au/ZnO:Al film