1,781 research outputs found
Covariant equations for the three-body bound state
The covariant spectator (or Gross) equations for the bound state of three
identical spin 1/2 particles, in which two of the three interacting particles
are always on shell, are developed and reduced to a form suitable for numerical
solution. The equations are first written in operator form and compared to the
Bethe-Salpeter equation, then expanded into plane wave momentum states, and
finally expanded into partial waves using the three-body helicity formalism
first introduced by Wick. In order to solve the equations, the two-body
scattering amplitudes must be boosted from the overall three-body rest frame to
their individual two-body rest frames, and all effects which arise from these
boosts, including the Wigner rotations and rho-spin decomposition of the
off-shell particle, are treated exactly. In their final form, the equations
reduce to a coupled set of Faddeev-like double integral equations with
additional channels arising from the negative rho-spin states of the off-shell
particle.Comment: 57 pages, RevTeX, 6 figures, uses epsf.st
Critical role for BIM in T cell receptor restimulation-induced death
<p>Abstract</p> <p>Background</p> <p>Upon repeated or chronic antigen stimulation, activated T cells undergo a T cell receptor (TCR)-triggered propriocidal cell death important for governing the intensity of immune responses. This is thought to be chiefly mediated by an extrinsic signal through the Fas-FasL pathway. However, we observed that TCR restimulation still potently induced apoptosis when this interaction was blocked, or genetically impaired in T cells derived from autoimmune lymphoproliferative syndrome (ALPS) patients, prompting us to examine Fas-independent, intrinsic signals.</p> <p>Results</p> <p>Upon TCR restimulation, we specifically noted a marked increase in the expression of BIM, a pro-apoptotic Bcl-2 family protein known to mediate lymphocyte apoptosis induced by cytokine withdrawal. In fact, T cells from an ALPS type IV patient in which BIM expression is suppressed were more resistant to restimulation-induced death. Strikingly, knockdown of BIM expression rescued normal T cells from TCR-induced death to as great an extent as Fas disruption.</p> <p>Conclusion</p> <p>Our data implicates BIM as a critical mediator of apoptosis induced by restimulation as well as growth cytokine withdrawal. These findings suggest an important role for BIM in eliminating activated T cells even when IL-2 is abundant, working in conjunction with Fas to eliminate chronically stimulated T cells and maintain immune homeostasis.</p> <p>Reviewers</p> <p>This article was reviewed by Dr. Wendy Davidson (nominated by Dr. David Scott), Dr. Mark Williams (nominated by Dr. Neil Greenspan), and Dr. Laurence C. Eisenlohr.</p
What’s Sex (Composition) Got to Do with It? The Importance of Sex Composition of Gangs for Female and Male Members’ Offending and Victimization
Sex composition of groups has been theorized in organizational sociology and found in prior work to structure female and male members’ behaviors and experiences. Peer group and gang literature similarly finds that the sex gap in offending varies across groups of differing sex ratios. Drawing on this and other research linking gang membership, offending, and victimization, we examine whether sex composition of gangs is linked to sex differences in offending in this sample, further assess whether sex composition similarly structures females’ and males’ victimization experiences, and if so, why. Self-report data from gang members in a multi-site, longitudinal study of 3,820 youths are employed. Results support previous findings about variations in member delinquency by both sex and sex composition of the gang and also indicate parallel variations in members’ victimization. These results are further considered within the context of facilitating effects such as gender dynamics, gang characteristics, and normative orientation
A New Supersymmetric CP Violating Contribution to Neutral Meson Mixing
We study the contribution to flavor changing neutral current processes from
box diagrams with light higgsinos and squarks. Starting with just the Cabbibo
Kobayashi Maskawa (CKM) phase, we find contributions to the and
meson mass matrices that are out of phase with the Standard Model contributions
in the case of substantial mixing between the up-type squarks. This difference
in phase could be large enough to be detected at the proposed factories,
with interesting implications for the unitarity triangle of CKM matrix
elements.Comment: 1 reference added, 1 reference clarified, 2 typos corrected (QCD
corrections to K meson mixing in Tables 1 and 3). To be published in Phys.
Rev. D. 15 pages (Latex), 2 figures and epsfig.sty submitte
Spin relaxation in low-dimensional systems
We review some of the newest findings on the spin dynamics of carriers and
excitons in GaAs/GaAlAs quantum wells. In intrinsic wells, where the optical
properties are dominated by excitonic effects, we show that exciton-exciton
interaction produces a breaking of the spin degeneracy in two-dimensional
semiconductors. In doped wells, the two spin components of an optically created
two-dimensional electron gas are well described by Fermi-Dirac distributions
with a common temperature but different chemical potentials. The rate of the
spin depolarization of the electron gas is found to be independent of the mean
electron kinetic energy but accelerated by thermal spreading of the carriers.Comment: 1 PDF file, 13 eps figures, Proceedings of the 1998 International
Workshop on Nanophysics and Electronics (NPE-98)- Lecce (Italy
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