241 research outputs found

    Production Capacity and Queues in a Bookstore at Porto Velho, Brazil

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    The objective of this work was to study the productive capacity and queues in the services of a bookstore in Porto Velho city, Brazil. To do this, the specific objectives were: (1) to study the productive capacity in the operation units of the bookstore; (2) to carry out an analysis of queuing and flow management in the operation units of the bookstore; and (3) to suggest prospects for the development using the SWOT Matrix analysis tool

    Ancient Exaptation of a CORE-SINE Retroposon into a Highly Conserved Mammalian Neuronal Enhancer of the Proopiomelanocortin Gene

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    The proopiomelanocortin gene (POMC) is expressed in the pituitary gland and the ventral hypothalamus of all jawed vertebrates, producing several bioactive peptides that function as peripheral hormones or central neuropeptides, respectively. We have recently determined that mouse and human POMC expression in the hypothalamus is conferred by the action of two 5′ distal and unrelated enhancers, nPE1 and nPE2. To investigate the evolutionary origin of the neuronal enhancer nPE2, we searched available vertebrate genome databases and determined that nPE2 is a highly conserved element in placentals, marsupials, and monotremes, whereas it is absent in nonmammalian vertebrates. Following an in silico paleogenomic strategy based on genome-wide searches for paralog sequences, we discovered that opossum and wallaby nPE2 sequences are highly similar to members of the superfamily of CORE-short interspersed nucleotide element (SINE) retroposons, in particular to MAR1 retroposons that are widely present in marsupial genomes. Thus, the neuronal enhancer nPE2 originated from the exaptation of a CORE-SINE retroposon in the lineage leading to mammals and remained under purifying selection in all mammalian orders for the last 170 million years. Expression studies performed in transgenic mice showed that two nonadjacent nPE2 subregions are essential to drive reporter gene expression into POMC hypothalamic neurons, providing the first functional example of an exapted enhancer derived from an ancient CORE-SINE retroposon. In addition, we found that this CORE-SINE family of retroposons is likely to still be active in American and Australian marsupial genomes and that several highly conserved exonic, intronic and intergenic sequences in the human genome originated from the exaptation of CORE-SINE retroposons. Together, our results provide clear evidence of the functional novelties that transposed elements contributed to their host genomes throughout evolution

    Mathematics as a Supporting Tool for Technological Management

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    The necessity of production involving the applicability of mathematics in the management decision-making process stimulates the elaboration of this article. This approach seeks to develop under a new profile of Mathematical Science, now as another tool of technological management, while it allows to understand the diverse deductive paradigms of this knowledge of support to the administrative process. In this way, the general objective is to deal with the application of mathematics as a tool in technological management; (1), to evaluate the applicability of these tools in the management of small and medium enterprises (2), to propose a mathematical model that contributes to the innovation of the business enterprise (3). The theoretical foundation is in the Taxonomy of Bloom, prescribed for the development of abilities and cognitive attitudes of the individual. There will be no doubt that mathematical problem-solving procedures advance significantly, especially to the demands of complex solutions. The Content Analysis Method and related procedures apply to this task. As a result .... Therefore, the study of mathematical and statistical application, in addition to computer resources to identify the possible trend in the index of technological management, the present article states that mathematics as a tool has its widespread applicability within the most diverse types of technological management, regardless of their size and showing how mathematics is associated in different areas of knowledge as a trend for technological management, since it is still considered for some as a difficult element among managers

    Prevalent Leadership Profile: A Research on Management of Innovation in the Military Organization

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    In this work we investigate prevailing leadership in a military organization. Our study has a multi-disciplinarily nature as it focuses on Organizational Innovation and the profile of a leader as well as a little investigation on history of the development of a military organization Our main objective is to identify the profile of a strategic prevalent leadership at the Firemen Corporation in Porto Velho, Rondonia – Northern Brazil. We propose to describe the process of nomination for someone to exercise the role of a leader used in the military structure. In this context, we make a survey of the prevalent elements considering the profile of leadership in the face of organizational innovation having in mind the expectation of the people involved in the process of research. At the end we conduct a critical analysis comparing the prevalent elements identified in our study with the expectation of innovation revealed by the military structure investigated. We apply the method of content analysis through convenient procedures. As a result, we present the elements which show prevalence for the definition of the leadership profile of the investigated military structure. We hope our research can contribute to the studies in the field of leadership, as we still have few references in the area of knowledge

    Strategic Paradigms of Social and Environmental Balance

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    Complaints about the socio-environmental relationship have become prominent, requiring the academy to deepen its studies on the strategic paradigms of sustainability. The objective of this essay is to study the conceptions of strategic paradigms along the path of social and environmental balance, with the specific objectives of raising the paradigms under social, economic, environmental and institutional aspects (1), analyzing the strategic paradigms that can favorably promote equilibrium (2), and critiquing the discourse of society, aiming at social and environmental balance (3). The elaboration of this work is based on the Institutionalist Theory that prescribes the set of individual behaviors, beliefs and values, processed in accordance with the individuals’ perception, and in their interpretative capacity of the reality in which they are inserted. This qualitative research is elaborated through the Method of Content Analysis, and applies procedures of bibliographical survey and documentary treatment of the social discourse that substantiates sustainable paradigms. As a result of the critical analysis, it is verified that the discourses and behaviors of the social agents do not contribute to the social-environmental balance. Then, new proposals of strategic paradigms which are useful for reflective actions and universal meanings are incorporated here. The expectation is to redirect the individual to behavioral reflections, through a learning that is coherent with the confrontation of the planetary emergency. It is also indicated for the spirit of preservation and conservation of the environment, in which the relationship with the social, economic and institutional will bring the desired balance for generations. This study represents those interested in the discussion about the socio-environmental relationship, and those involved in learning about sustainability and orientation towards ethical posture

    Green Purchases and Sustainability in Amazon’s Coffee Management

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    This study was conceived in the cradle of the Brazilian Amazon region, on managerial and cognitive knowledge of the perspectives of sustainable management in coffee cultivation. The objective is to study the green purchasing process and sustainability in coffee management; (1), to map the factors that interfere in the green purchasing processes and sustainability in the researched scenario (2), propose the innovation required with participative management in the face of sustainability with green purchasing (3). With a base on Contingency theories of adaptive nature and emerging demands, Ecodevelopment interprets and performs compatible actions for sustainable local development, the U Theory confronts the problems and transforms them with innovative solutions. The Method of Study adopted is the Case study, of a qualitative nature, such as bibliographic survey procedures, data collection by semi-structured interviews with social actors of the coffee system, data analysis through triangulation and criticism with the theoretical framework and construction of the innovation sustainable development proposal. The result shows the lack of knowledge about green purchasing and the sustainability aspect of the practices used in the Global Coffee Platform. The quality work of the coffee farmers was evidenced in an individual form, but in order to meet the quantitative demands of the market, it is required the structural and leadership development for the construction of APL or agricultural cooperative. The mental design configured at the base of the productive chain needs to break paradigms that interfere in the sustainable posture, to understand the needs of the consumers and to emphasize their participation on the responsibility with the Amazon and the beneficiary society as a whole. We presented suggestions of innovation discussed from the gaps detected by the mapping of factors

    Application of the Quick Tool Exchange (QTE) System in Building Maintenance

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    Quick Tool Exchange (QTE) acts to reduce losses and failures during the production process and throughput time, contributing to rapid response to market changes. The object of the work is a private school of the Municipality of Porto Velho, capital of Rondônia. The general objective is to study the building maintenance of a private school in the Municipality of Porto Velho / RO, focusing on QTE technology. Therefore, the specific objectives were to characterize the building maintenance in the study (1); compare the operational processes applied in the face of QTE concepts (2); and propose innovation for the operational improvement of building maintenance in operation (3). The building maintenance has a clear importance, since its compliance contributes to the preservation of life and health of users of any construction. Both the preventive and the corrective have been receiving the importance due to it, especially the preventive one, since this is always cheaper in comparison to the corrective one, since besides the damages caused to the physical structure of the building, there can exist to the users present in the occurrence of the fact. The methodological procedures consisted in carrying out a bibliographic survey followed by a case study. The results demonstrated measures approved and not approved by the QTE, suggesting simple innovations, but with significant consequences to the improvement of service rendering, minimizing costs in the area of building maintenance. This study is of interest to businessmen in general, especially the public or private educational sector, and those involved with the area of Production Administration
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