TINGKAT PENGETAHUAN DAN SIKAP MAHASISWA TERHADAP TINDAKAN BANTUAN HIDUP DASAR DI UNIVERSITAS SRIWIJAYA

Tujuan: Tujuan penelitian ini adalah untuk menganalisis pengetahuan dan sikap terhadap bantuan hidup dasar pada mahasiswa Universitas Sriwijaya. Metode: Penelitian ini dilakukan dengan desain deskriptif analitik dan menggunakan teknik purposive sampling dengan kuota sampling. Pengambilan data menggunakan kuesioner secara online yang disebarkan kepada mahasiswa tingkat akhir dari sembilan fakultas di Universitas Sriwijaya. Hasil: Sebanyak 418 mahasiswa yang mengikuti penelitian ini. Hasil penelitian menemukan bahwa lebih dari setengah responden (59,1%) memiliki tingkat pengetahuan yang cukup baik tentang bantuan hidup dasar dan 57,9% memiliki sikap yang cukup terhadap tindakan bantuan hidup dasar. Simpulan: Meskipun tingkat pengetahuan tentang bantuan hidup dasar cukup baik, namun perlu pemberian informasi dan edukasi mengenai bantuan hidup dasar bagi mahasiswa sebagai kelompok awam dalam penanganan korban yang membutuhkan bantuan hidup dasar di komunitas. Pelatihan mengenai bantuan hidup dasar juga diperlukan agar meningkatkan sikap dan keterampilan dalam melakukan tindakan bantuan hidup dasar. Kata kunci: bantuan hidup dasar, mahasiswa, pengetahuan, sikap

Effect of methanol extracts of nony fruit on mice infected by RH strain of Toxoplasma gondii

Intraperitoneal infection of Type I Toxoplasma gondii on mice causes high mortality at a short time due to parasitic burden, immunosuppression, cell and tissue damage. The mice survival is increased after treated with drugs that reduce or destroy tachyzoite and modulate or recovered the immune system. Nony fruit (Morinda citrifolia) is popular as immunomudulator and has antoxoplasma properties. The purpose of this experiment is to evaluate the effect of ethanol extract of nony fruit and Fansidar® (pyrimethamine-sulfadiazine) to reduce tachyzoite and improve survival as well as immunomudulator on mice following toxoplasma infection. Mice was divided into six groups (10 mice respectively) consist of infected-non treated groups, infected + Fansidar®, infected + ethanol extract of nony on several doses (100, 50, 25%) and non infected-non treated groups. All mice on each groups were infected intraperitoneally by 5 x 106 and 2,5 x 103 RH strain of Toxoplasma gondii tachyzoite/mice respectively. The results have shown that Fansidar® was successfully to reduced tachyzoite and improved mice survival but the ethanol extract of nony fruit was failed.     Key Words: Survivality, Immunomodulator, Toxoplasma gondii, Nony extract

Effect of methanol extracts of nony fruit on mice infected by RH strain of Toxoplasma gondii

Intraperitoneal infection of Type I Toxoplasma gondii on mice causes high mortality at a short time due to parasitic burden, immunosuppression, cell and tissue damage. The mice survival is increased after treated with drugs that reduce or destroy tachyzoite and modulate or recovered the immune system. Nony fruit (Morinda citrifolia) is popular as immunomudulator and has antoxoplasma properties. The purpose of this experiment is to evaluate the effect of ethanol extract of nony fruit and Fansidar® (pyrimethamine-sulfadiazine) to reduce tachyzoite and improve survival as well as immunomudulator on mice following toxoplasma infection. Mice was divided into six groups (10 mice respectively) consist of infected-non treated groups, infected + Fansidar®, infected + ethanol extract of nony on several doses (100, 50, 25%) and non infected-non treated groups. All mice on each groups were infected intraperitoneally by 5 x 106 and 2,5 x 103 RH strain of Toxoplasma gondii tachyzoite/mice respectively. The results have shown that Fansidar® was successfully to reduced tachyzoite and improved mice survival but the ethanol extract of nony fruit was failed