Climate technology transfer at the local, national and global levels: analyzing the relationships between multi-level structures

This thesis examines the relationships between multi-leveled decision structures for climate technology transfer through an analysis of top-down macro-policy and bottom-up micro-implementation. It examines how international climate technology transfer policy under the UNFCCC filters down to the national policies that govern the micro entities, such as firms and companies. Similarly, the thesis examines how climate technology transfer practices at the firm level are reflected in national strategies and molded by international climate policies.\ud Specifically, the thesis addresses the research question: what is the relationship between firm practices, national policies, and internatinoal discourses for climate technology transfer, and if there is a disjunction, then why? In order to analyze these relationships, the thesis locates technology transfer as a response to climate change at the interface between three factors: (1) technology transfer issues that have always been at the forefront of the global climate change debate (2) the objective of technology transfer for achieving low-carbon climate resilient national socio-economic development aspirations and (3) the effectiveness of technology transfer at the firm level in decreasing GHG emissions.\ud The thesis concludes by addressing the research question of whether the three levels (international, national and local) are more weakly coupled than is needed for effective climate technology transfer. The loose interconnections between the three levels in the intense interplay of top-down and bottom-up processes have resulted in a mixture of coherent and incoherent relationships between the three levels. Results from combining top-down macro-policy analysis (mainly in Chapters 4 and 5) with bottom-up micro-implementation analysis (mainly in Chapter 6) reveal the existence of the different level of coherence between the multi-leveled decision structures for climate technology transfer. The research shows that there is a relatively sound accord between international climate technology transfer discourses under the UNFCCC and national technology transfer policy. There is also good congruity between national policy and firm-level climate technology transfer practices. However, there is a clear disjunction between the international and local level

Global value chain governance for resource efficiency building sustainable consumption and production bridges across the global sustainability divides

This paper looks at improving resource productivity at global value chains. Resource flows from its extraction through the manufacturing and use phase towards its end-of-life – increasingly crossing national boundaries. Effective improvement in resource productivity requires actions beyond a country’s territory. This article focuses on non-renewable resource flows and analysis how developed countries are involved in four distinct phases of global value chains, and how this involvement links to changes in resource efficiency. Resource extraction and associated early processes activities have been increasingly moved from developed to developing countries. Offshoring manufacturing activities also becomes a common phenomenon. Throughout these activities, lower rates of resource productivity during extraction and manufacturing are frequently observed, leading not only to international burden shifting, but most likely letting these burdens grow. If appropriate international measures across the global divides are applied, resource efficiency potentials could be realised through offshoring and global consumption and recycling could also offer opportunities for resource productivity. International actions to improve resource productivity can help to meet economic and environmental objectives at the same time over a global value chain. It could also safeguard countries against unintended indirect and side effects from the relocation of resource flows and help the private sector to benefit from opportunities in global markets for resource efficiency

Hospital based surveillance of congenital rubella syndrome cases in the pre-vaccine era in Amhara Regional State, Ethiopia: A base line information for the country.

BACKGROUND:Rubella virus infection in early pregnancy lead to serious multi-organ birth defects known as congenital rubella syndrome (CRS). The incidence of CRS varies in different populations and the highest burden is found in developing countries in which rubella vaccination is not included in their national immunization programs. In Ethiopia, there is scarcity of data about congenital rubella syndrome. Therefore, the aim of this study was to determine the burden of CRS-related birth defects and its incidence in the pre-vaccine era in Amhara Regional State, Ethiopia. MATERIALS AND METHODS:A cross sectional study was conducted in Dessie, Felege-Hiwot and University of Gondar Referral Hospitals, from December 2015 to August 2017. After getting informed assent from each parent/guardian, blood was collected from infants < 1 year of age for laboratory determination of anti-rubella virus antibodies. Their socio-demographic data and clinical information compatible with congenital rubella syndrome were collected using WHO guideline. RESULTS:During the study period, a total of 50 infants suspected for congenital rubella syndrome were included in the study. All infants suspected for CRS were tested against rubella specific IgM and IgG [for infants ≥ 6 months of age] antibodies using ELISA method. Of these, 9/50 (18%) and 4/14 (28.6%) of them were laboratory confirmed and potential CRS cases, respectively. In the present study, the most common laboratory confirmed defect was ocular manifestations 6 (66.7%) followed by heart related problems 5 (55.6%). In the present study, most of the laboratory confirmed cases (66.7%) were reported among 1-5 months of age infants. In addition, 5 (55.6%) of the infants with laboratory confirmed CRS cases were male and 6 (66.7%) of them were from urban settings. In this study, the incidence of CRS was 0.4 per 1000 live births. CONCLUSION:In this study, nearly one fifth of the infants had laboratory confirmed congenital rubella syndrome and most of them had multiple rubella associated congenital defects at a time. Most of these congenital anomalies were reported among infants ≥ 1 month of age. Based on our result, the incidence of the CRS was line with the global incidence of the CRS in the pre-vaccine era. Therefore, establishing strong rubella/CRS surveillance system as well as introducing the rubella containing vaccine in the national immunization program might be important to reduce the burden of rubella and CRS in the country

Molecular and Immunological Diagnostic Techniques of Medical Viruses

Viral infections are causing serious problems in human population worldwide. The recent outbreak of coronavirus disease 2019 caused by SARS-CoV-2 is a perfect example how viral infection could pose a great threat to global public health and economic sectors. Therefore, the first step in combating viral pathogens is to get a timely and accurate diagnosis. Early and accurate detection of the viral presence in patient sample is crucial for appropriate treatment, control, and prevention of epidemics. Here, we summarize some of the molecular and immunological diagnostic approaches available for the detection of viral infections of humans. Molecular diagnostic techniques provide rapid viral detection in patient sample. They are also relatively inexpensive and highly sensitive and specific diagnostic methods. Immunological-based techniques have been extensively utilized for the detection and epidemiological studies of human viral infections. They can detect antiviral antibodies or viral antigens in clinical samples. There are several commercially available molecular and immunological diagnostic kits that facilitate the use of these methods in the majority of clinical laboratories worldwide. In developing countries including Ethiopia where most of viral infections are endemic, exposure to improved or new methods is highly limited as these methods are very costly to use and also require technical skills. Since researchers and clinicians in all corners of the globe are working hard, it is hoped that in the near future, they will develop good quality tests that can be accessible in low-income countries