Perspectief natuurlijke keringen: een eerste verkenning ten behoeve van het Deltaprogramma

In het Deltaprogramma staan de waterveiligheid en de watervoorziening van Nederland nu en voor de lange termijn centraal. In de aanpak wordt actief gezocht naar de koppeling met andere ambities van rijk, provincies, waterschappen, gemeenten, maar ook van maatschappelijke organisaties en bedrijven op andere beleidsterreinen, zoals economie, natuur en ruimte. De Deltacommissaris heeft de Stichting Ecoshape gevraagd de mogelijkheden te verkennen voor het toepassen van natuurlijke keringen in het IJsselmeergebied, de Wadden en estuaria en het rivierengebie

Sustainability in supply and value chain management

This chapter presents the case for integrating sustainability principles into supply and value chain management provision at higher education level as an urgent matter for consideration. It draws on the key declarations including Global Action Programme (GAP) of UNESCO that support the incorporation of sustainability values and practices into all aspects of learning to underscore the need for embedding supply and value chain management curriculum with sustainability. The shared experience and insights from scholarly engagement with integrating sustainability principles at three levels in higher education facilitates sustainability knowledge transfer. Grounded in the extant literature, a critical discussion of the integration process including pedagogical practices reveals prospects and challenges to scaling up of sustainable supply and value chain management education

The Basal Levels of Active and Inactive Plasma Renin Concentration in Infancy and Childhood

1. Basal plasma renin activity, active and inactive plasma renin concentration were measured in 89 healthy recumbent children aged between 1 week and 16 years. 2. A significant (P&amp;lt;0.001) age-related decrease for active (r = −0.60), inactive (r = −0.59) and total renin concentration (r = −0.66) was observed. 3. After correction for the influence of age, active renin concentration correlated with plasma renin activity (r = 0.81), but not with inactive renin concentration (r = 0.18). 4. The proportions of active and inactive renin were not related to age, and the overall percentage of inactive renin was 79%.</jats:p

A Dietary Fiber Mixture versus Lactulose in the Treatment of Childhood Constipation: A Double-blind Randomized Controlled Trial

Background: Constipation is a common problem in children. As first-line treatment, increased dietary fiber is often advocated. To our knowledge. however, no large Studies evaluating the effect of dietary fibers in childhood constipation have been published. Patients and Methods: A randomized, double-blind, prospective controlled Study was performed. Patients received either a fiber mixture or lactulose in a yogurt drink. After a baseline period of a week, patients were treated for 8 weeks followed by 4 weeks of weaning. Polyethylene glycol 3350 was added if no clinical improvement was observed after 3 weeks. Using a standardized bowel diary. parents recorded defecation frequency during the treatment period. In addition, incontinence frequency. stool consistency. presence of abdominal pain and flatulence. necessity for step-up medication, and dry weight of feces were recorded, as were adverse effects. Results: A total of 147 children were eligible 12 children wished not to participate. Of the remaining children, 65 were randomized to treatment with fiber Mixture and 70 to treatment with lactulose. In ally 97 children completed the study. No difference was found between the groups after the treatment period concerning defecation frequency (P=0.481) and fecal incontinence frequency (P=0.084). However, consistency of stools was softer in the lactulose group (P = 0.01). Abdominal pain and flatulence scores were comparable (P=0.395 and P = 0.739. respectively). The necessity of step-up medication during the treatment period was comparable (P=0.996), as were taste scores (P=0.657). No serious adverse effects were registered. Conclusions: A fluid fiber mixture and lactulose give Comparable results in the treatment of childhood constipation. JPGN 47:592-597, 200

Effects of sulfasalazine treatment on serum immunoglobulin levels in children with juvenile chronic arthritis

This article describes the effects of sulfasalazine (SSZ) treatment on serum immunoglobulin (Ig) levels in 6 children with oligoarticular- or polyarticular onset juvenile chronic arthritis (JCA). None of the children who developed dysimmunoglobulinemia during treatment showed clinical symptoms of this adverse event, in particular none developed severe infections. All patients regained normal immunoglobulin levels after discontinuing SSZ treatment. One patient with a partial IgA deficiency at the start of SSZ treatment showed a slow increase in the IgA level during treatment. During follow-up (4-6 years), one patient spontaneously developed a dysimmunoglobulinemia and one patient developed diabetes mellitus. Based on these case reports and review of the literature we advocate monitoring of serum immunoglobulin levels while on SSZ treatment