Persistent memory in athermal systems in deformable energy landscapes

We show that memory can be encoded in a model amorphous solid subjected to athermal oscillatory shear deformations, and in an analogous spin model with disordered interactions, sharing the feature of a deformable energy landscape. When these systems are subjected to oscillatory shear deformation, they retain memory of the deformation amplitude imposed in the training phase, when the amplitude is below a "localization" threshold. Remarkably, multiple, persistent, memories can be stored using such an athermal, noise-free, protocol. The possibility of such memory is shown to be linked to the presence of plastic deformations and associated limit cycles traversed by the system, which exhibit avalanche statistics also seen in related contexts.Comment: 5 pages, 4 figure

Bioprospecting antimicrobials from lactiplantibacillus plantarum: Key factors underlying its probiotic action

Lactiplantibacillus plantarum (L. plantarum) is a well‐studied and versatile species of lactobacilli. It is found in several niches, including human mucosal surfaces, and it is largely employed in the food industry and boasts a millenary tradition of safe use, sharing a long‐lasting relationship with humans. L. plantarum is generally recognised as safe and exhibits a strong probiotic character, so that several strains are commercialised as health‐promoting supplements and functional food products. For these reasons, L. plantarum represents a valuable model to gain insight into the nature and mechanisms of antimicrobials as key factors underlying the probiotic action of health‐promoting microbes. Probiotic antimicrobials can inhibit the growth of pathogens in the gut ensuring the intestinal homeostasis and contributing to the host health. Furthermore, they may be attractive alternatives to conventional antibiotics, holding potential in several biomedical applications. The aim of this review is to investigate the most relevant papers published in the last ten years, bioprospecting the antimicrobial activity of characterised probiotic L. plantarum strains. Specifically, it focuses on the different chemical nature, the action spectra and the mechanisms underlying the bioactivity of their antibacterial and antiviral agents. Emerging trends in postbiotics, some in vivo applications of L. plantarum antimicrobials, including strengths and limitations of their therapeutic potential, are addressed and discussed

Geophysics

Contains reports on four research projects.United States Air Force (Contract AF19(628)-500)Lincoln Laboratory (Purchase Order DDL BB-107

Geophysics

Contains reports on three research projects

Plasma Electronics

Contains reports on six research projects.United States Navy, Office of Naval Research (Contract Nonr-1841(78))Lincoln Laboratory (Purchase Order DDL B-00337)United States ArmyUnited States Air Force (Contract AF19(604)-7400)United States NavyNational Science Foundation (Grant G-9330

Radio Astronomy

Contains reports on four research projects.National Science Foundation (Grant G-13904)National Aeronautics and Space Administration (Contract NaSr-101)National Aeronautics and Space Administration (Grant NsG-250-62

Optical coherence tomography for patch test grading: A prospective study on its use for noninvasive diagnosis of allergic contact dermatitis

Background: The diagnosis of allergic contact dermatitis should be confirmed by skin patch tests. Distinguishing between irritant and allergic reactions is sometimes difficult. Objectives: To analyse the in vivo morphological changes in patch test reactions compared to healthy skin, and to detect subclinical changes in doubtful reactions using optical coherence tomography (OCT). To develop an OCT-based algorithm to support patch-test grading. Methods: One hundred twenty-nine skin patch-test areas were scanned with OCT to evaluate the following features: architectural and vascular morphology, epidermal thickness, optical attenuation coefficient (AC), and blood flow at 0.1, 0.2, and 0.35 mm depth. Results: Most common OCT features of acute contact allergic reactions in patch tests were spongiosis with microvesicles (94.8%), macrovesicles (60.3%), and coalescing vesicles (46.6%), the latter useful in differentiating acute allergic from irritant dermatitis (P-value <.05). Objective quantitative parameters correlated well with the severity grade: epidermal thickness due to spongiosis, AC (P-value <.05) and blood flow at 0.2 and 0.35 mm (P-value <.01). Conclusions: OCT as a noninvasive diagnostic tool, established for skin cancer diagnosis, is useful for evaluating contact allergic patch-test reactions. Not only morphological but also objective features such as blood flow and AC correlate with the reaction severity. Further studies are needed to explore the differences in irritant and allergic contact dermatitis

Chemical modification of wood induced by the traditional making procedures of bowed string musical instruments: the effect of alkaline treatments

Over the last few decades, chemical and physical studies on bowed string musical instruments have provided a better understanding of their wooden finished surface. Nevertheless, until now only a few of them investigated the effects of the chemical pre-treatments in the traditional making procedures. Those treatments are believed to affect wood properties, its interaction with the following treatments (i.e. varnish application) and its vibro-mechanical behaviour (that may contribute to the acoustical properties of musical instruments). In this study, two traditional alkaline treatments were applied to reference samples of spruce wood, the wood commonly used to make violins’ soundboards. An integrated analytical strategy, which combines infrared spectroscopy, analytical pyrolysis coupled to gas chromatography-mass spectrometry, and gel permeation chromatography, was employed to investigate the chemical alterations of lignocellulosic polymers (cellulose, hemicellulose, and lignin). Results have shown that the selected alkaline treatments induce the partial hydrolysis of the hemicellulose chains and a slight decrease in the crystallinity of cellulose. We could also prove: (i) the cleavage of lignin-carbohydrate complexes formed by the covalent bonds between hemicellulose and lignin in spruce wood, and (ii) the partial breaking of the hydrogen bonds network in cellulose. According to the literature, the alteration of the lignin-carbohydrate complexes is responsible for changes in wood mechanical behaviour. Hence, future perspectives of this research could outline new knowledge on the vibro-mechanical behaviour of the violin soundboard and the consequent acoustics

X-rays investigations for the characterization of two 17th century brass instruments from Nuremberg

A recent finding at the Castello Sforzesco in Milan of two brass natural horns from the end of the 17th century and assigned to the Haas family from Nuremberg brought to light new information about this class of objects. The instruments were heavily damaged, but their historical value was great. In this study, a multidisciplinary approach mainly based on non-invasive analytical techniques and including X-rays investigations (X-ray radiography, X-ray fluorescence and X-ray diffraction) was used. The present study was aimed at: i) pointing out the executive techniques for archaeometric purposes; ii) characterizing the morphological and the chemical features of materials; and iii) identifying and mapping the damages of the structure and the alterations of the surface

Surface and interface treatments on wooden artefacts: Potentialities and limits of a non-invasive multi-technique study

Wooden artefacts embrace wide-ranging types of objects, like paintings on panel, sculptures, musical instruments, and furniture. Generally, in the manufacturing process of an artwork, wood is firstly treated with organic and inorganic materials to make it nonporous and morphologically homogeneous, and, at last, the surface treatment consists of varnishes or coatings applied with the aims of conferring aesthetic properties and protecting wood from biological growth and external degradation agents, as well as mechanical damage. In this work, different wooden mock-ups were prepared by varying some parameters: concentration of filler and pigment, respectively, in the ground and paint layers, thickness of the protective varnish coat, and sequence of the layers. The mock-ups were subsequently exposed to time-varying artificial aging processes. The multi-analytical non-invasive approach involved spectroscopic (reflection FT-IR, Raman, and X-ray fluorescence), tomographic (optical coherence tomography) and colorimetric techniques. Data were interpreted using both univariate and multivariate methods. The aim was to evaluate potential and limits of each non-invasive technique into the study of different stratigraphies of wooden artworks. This approach was supported by microscopic observations of cross-sections obtained from selected mock-ups. The methodological approach proposed here would add valuable technical know-how and information about the non-invasive techniques applied to the study of wooden artworks