Chiral Lagrangians with tensor sources

The implementation of tensor sources in Chiral Lagrangians allows the computation of Green functions and form factors involving tensor currents, that is, quark bilinears of the form \bar{q}_i\sigma^{\mu\nu}q_j. Whereas only four new terms show up at O(p^4), we find around a hundred of them at O(p^6). So it becomes essential to ensure that this set o operators is indeed minimal and non-redundant (i.e., it is a basis). We discuss two phenomenological applications in the context of vector meson resonances and the radiative pion decay.Comment: Talk given at the 4th International Worshop on Quantum ChromoDynamics, Theory and experiment, June 16-20, 2007. Martina Franca - Valle d'Itria - Ital

Association of a homozygous GCK missense mutation with mild diabetes

Background: Homozygous inactivating GCK mutations have been repeatedly reported to cause severe hyperglycemia, presenting as permanent neonatal diabetes mellitus (PNDM). Conversely, only two cases of GCK homozygous mutations causing mild hyperglycemia have been so far described. We here report a novel GCK mutation (c.1116G>C, p.E372D), in a family with one homozygous member showing mild hyperglycemia. Methods: GCK mutational screening was carried out by Sanger sequencing. Computational analyses to investigate pathogenicity and molecular dynamics (MD) were performed for GCK-E372D and for previously described homozygous mutations associated with mild (n = 2) or severe (n = 1) hyperglycemia, used as references. Results: Of four mildly hyperglycemic family-members, three were heterozygous and one, diagnosed in the adulthood, was homozygous for GCK-E372D. Two nondiabetic family members carried no mutations. Fasting glucose (p = 0.016) and HbA1c (p = 0.035) correlated with the number of mutated alleles (0–2). In-silico predicted pathogenicity was not correlated with the four mutations’ severity. At MD, GCK-E372D conferred protein structure flexibility intermediate between mild and severe GCK mutations. Conclusions: We present the third case of homozygous GCK mutations associated with mild hyperglycemia, rather than PNDM. Our in-silico analyses support previous evidences suggesting that protein stability plays a role in determining clinical severity of GCK mutations

Dynamics and Hadronization at intermediate transverse momentum at RHIC

The ultra-relativistic heavy-ion program at RHIC has shown that at intermediate transverse momenta ($p_T \simeq 2$-6 GeV) standard (independent) parton fragmentation can neither describe the observed baryon-to-meson ratios nor the empirical scaling of the hadronic elliptic flow ($v_2$) according to the number of valence quarks. Both aspects find instead a natural explanation in a coalescence plus fragmentation approach to hadronization. After a brief review of the main results for light quarks, we focus on heavy quarks showing that a combined fragmentation and quark-coalescence framework is relevant also here. Moreover, within relativistic Langevin simulations we find evidence for the importance of heavy-light resonances in the Quark-Gluon Plasma (QGP) to explain the strong energy loss and collective flow of heavy-quark spectra as inferred from non-photonic electron observables. Such heavy-light resonances can pave the way to a unified understanding of the microscopic structure of the QGP and its subsequent hadronization by coalescence.Comment: Proceedings of the International Workshop on QCD - Martina Franca (Italy), June 2007. To be published in AIP. 6 pages, 6 figure

An integrated overview of physiological and biochemical responses of Celtis australis to drought stress

Trees in Mediterranean areas frequently face severe drought stress events, due to sudden decreases in soil water availability associated to intense heat waves. The knowledge of strategies adopted by plants to cope with the environmental pressures associated to Mediterranean climate is crucial for reforestation strategies and planning future urban greening. Here we investigated the physiological and biochemical adjustments activated by Celtis australis in response to drought stress during summer. Despite widely used for reforestation in Southern Mediterranean, how C. australis responds to the severe challenges imposed by Mediterranean climate has not investigated yet. In our study, we performed analyses of water relations, gas exchange and PSII performance, the concentration of photosynthetic pigments, the activity and the concentration of primary antioxidants in plants exposed to drought stress of increasing severity. Data of our study reveal that C. australis displays both conservative water use and isohydric behavior in response to drought, and diffusive resistance mostly limits photosynthesis even at severe drought. Our study also reveals an effective down-regulation rather than permanent impairment of PSII photochemistry in response to drought stress of increasing severity, since excess electron transport due to declines in photosynthesis (-61% at severe stress, compared to control) was matched by an increase in nonphotochemical quenching (+71% at severe stress, compared to control). However, our study highlights that under severe drought, zeaxanthin (and neoxanthin) increased by 75% (and 25%), likely served an important function as chloroplast antioxidant, other than sustaining nonphotochemical quenching. Antioxidant enzymes and ascorbate also increased (+132% on average for superoxide dismutase, ascorbate peroxidase, and catalase) and contributed in countering oxidative stress in severely droughted plants. Large adjustments in the suite of physiological and biochemical traits may effectively enable C. australis to gain carbon at appreciable rates while avoiding irreversible damage to the photosynthetic apparatus even when challenged by severe drought stress, thereby making this species an excellent candidate for forest and urban plantings in sites experiencing extended periods of drought stress

Organocatalysis and beyond: Activating reactions with two catalytic species

Since the beginning of the millennium, organocatalysis has been gaining a predominant role in asymmetric synthesis and it is, nowadays, a foundation of catalysis. Synergistic catalysis, combining two or more different catalytic cycles acting in concert, exploits the vast knowledge acquired in organocatalysis and other fields to perform reactions that would be otherwise impossible. Merging organocatalysis with photo-, metallo- and organocatalysis itself, researchers have ingeniously devised a range of activations. This feature review, focusing on selected synergistic catalytic approaches, aims to provide a flavor of the creativity and innovation in the area, showing ground-breaking examples of organocatalysts, such as proline derivatives, hydrogen bond-mediated, Cinchona alkaloids or phosphoric acids catalysts, which work cooperatively with different catalytic partners

Optical delay control of large-spectral-bandwidth laser pulses

In this letter we report the first experimental observation of temporal delay control of large-spectral-bandwidth multimode laser pulses by means of electromagnetically induced transparency (EIT). We achieved controllable retardation with limited temporal distortion of optical pulses with an input spectral bandwidth of 3.3 GHz. The experimental results compare favorably with theoretical predictions.Comment: Submitted to Optics Letters (January 2009

Co-axial dual-core resonant leaky fibre for optical amplifiers

We present a co-axial dual-core resonant leaky optical fibre design, in which the outer core is made highly leaky. A suitable choice of parameters can enable us to resonantly couple power from the inner core to the outer core. In a large-core fibre, such a resonant coupling can considerably increase the differential leakage loss between the fundamental and the higher order modes and can result in effective single-mode operation. In a small-core single-mode fibre, such a coupling can lead to sharp increase in the wavelength dependent leakage loss near the resonant wavelength and can be utilized for the suppression of amplified spontaneous emission and thereby gain equalization of an optical amplifier. We study the propagation characteristics of the fibre using the transfer matrix method and present an example of each, the large-mode-area design for high power amplifiers and the wavelength tunable leakage loss design for inherent gain equalization of optical amplifiers.Comment: 6 page