Is There a Relationship between Mood Disorders and Dysmenorrhea?

WOS: 000345057100012PubMed: 25256879Objective: Menstrual problems are common among adolescent females. Mood changes are related to menstrual problems (menorrhagia, dysmenorrhea, and abnormal menstrual cycle length). the aim of this study was to determine the relationship between depressive symptoms, anxiety, and premenstrual syndrome (PMS) with dysmenorrhea in adolescent girls. Methods: A total of 159 adolescent girls (aged 13-19 y) with regular menstrual cycles presenting to the gynecology clinic with any complaints were included in the study during April-May 2013. All of the participants filled up the sociodemographic data collection form, FACES Pain Rating Scale, Beck anxiety inventory (BAI), Beck depression inventory (BDI), and a questionnaire form on criteria for PMS. Mann-Whitney U and chi-square tests were used to analyze the data. Results: the prevalence of dysmenorrhea was 67.9%. the mean BAT and BDI scores of the patients were 13.64 +/- 12.81 and 11.88 +/- 10.83, respectively. Statistically significant differences were observed between patients and control groups on the BAI and BDI scoring (P < .05). At least 1 of the symptoms of the PMS was detected in all of the participants and 29 (18.2%) of them were diagnosed as premenstrual dysphoric disorder (PMDD). the mean BAI score of the patients with PMS and PMDD were 9.65 +/- 9.28 and 21.31 +/- 15.75, respectively. the mean BDI score of the patients with PMS and PMDD were 8.39 +/- 8.62 and 19.1 +/- 11.85, respectively. Statistically significant differences were observed between PMS/PMDD and BAI/BDI scoring (P = .00). Conclusion: Adolescent girls with dysmenorrhea have an increased risk of depression and anxiety. These results of our study are significant in emphasizing the importance of a multidisciplinary approach to primary dysmenorrhea follow-up and treatment

Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in patients with endometrial hyperplasia and endometrial cancer

WOS: 000351218500016PubMed: 25363740AimNeutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and platelet distribution width (PDW) may indicate the systemic inflammatory response associated with various cancers. We aimed to investigate the relationship between NLR, PLR, PDW and endometrial pathologies including hyperplasia and cancer. MethodsIn this study, 472 cases who underwent endometrial biopsy were included. Three groups were constituted with respect to biopsy results: group 1, endometrial cancer patients (n=54); group 2, endometrial hyperplasia patients (n=152); and group 3, patients with normal biopsy results (n=281). White blood cell and platelet counts as well as NLR, PLR and PDW recorded from complete blood counts obtained on the same day of biopsy were compared in the three groups. ResultsEndometrial cancer patients were significantly older than the cases in the other two groups (P<0.001). the NLR in group 1 was significantly higher than group 3 (P=0.02). However, there was no difference between the three groups with respect to PLR (P=0.167). PDW was increased in group 1 compared to group 3 (P<0.001). ConclusionResults of our study have shown that NLR, PLR and PDW are simple, readily available and robust inflammatory markers that may be used in the management of endometrial pathologies. However, the actual predictive potential of these biomarkers still warrants further trials

Comparison of hematologic variables and NGAL levels of premenopausal overweight women with and without PCOS

WOS: 000372180000507[No abstract available

Disability and psychiatric symptoms in hyperemesis gravidarum patients

Ustuner, Isik/0000-0002-3791-4071WOS: 000329222100011PubMed: 23807698Nausea and vomiting is an important health problem which adversely affects the daily routine and quality of life in pregnant women. the purpose of this study was to measure the level of change in the quality of life, depression and anxiety in hyperemesis gravidarum (HG) patients in relation to social-demographic data and disease variables. One hundred pregnant women hospitalized with the diagnosis of HG were included in the study. A total of 100 healthy pregnant women were also evaluated as the control group. All the patients in the study completed the socio-demographic data form, the Hospital Anxiety and Depression Scale (HADS-A and D) and Brief Disability Questionnaire (BDQ). the mean HADS-D subscale score was 7.09 +/- 3.91 in HG patients and 5.73 +/- A 3.32 in controls. the depression score in the HG patients were significantly higher than that of the control group (p = 0.009). the mean HADS-A subscale score was 7.73 +/- A 3.86, which was significantly higher in HG patients compared to 6.70 +/- A 3.31 in controls (p = 0.045). the mean BDQ score was 11.2 +/- A 4.40 in HG patients and 8.5 +/- A 3.31 in the control group of pregnant women, thus, significantly higher in the HG group as compared to controls (p < 0.0001). in the HADS-D, 52 patients in the HG group and 40 patients in the control group scored above the threshold value (p = 0.089). in the HADS-A, 28 patients in the HG group and 20 in the control group scored above the threshold value (p = 0.185). in patients with HG, a significant deterioration of physical and social health was encountered. HG disease is independent of any underlying psychiatric condition and adversely affects the quality of life of the sufferer

Could platelet distribution width be a predictive marker for unexplained recurrent miscarriage?

WOS: 000339727400009PubMed: 24619190The aim of our study was to evaluate the platelet function in unexplained recurrent miscarriage and to investigate whether any hematologic changes detectable by simple complete blood count have a diagnostic value for the prediction of unexplained recurrent miscarriage. A prospective study based on the comparison of 74 patients with unexplained recurrent first-trimester pregnancy loss with 208 control subjects matched for age. the two groups were compared in terms of platelet indices. There was a significant difference in platelet distribution width in patients with unexplained recurrent miscarriage compared to healthy control subjects. Platelet distribution width values in the patient group were statistically higher (P < 0.001) than the control group. Our study provides an evidence that platelet distribution width gradually increases in women with recurrent miscarriage compared to control group. Patients with unexplained recurrent miscarriage have significantly increased platelet aggregation. This data may provide an empirical rationale for the use of anticoagulants in the management of this clinical condition

Chronic Abdominal Pain in a Patient with Escobar Syndrome

Erdivanli, Basar/0000-0002-3955-8242WOS: 000348046600011PubMed: 25196531Escobar syndrome is characterized with multiple pterygia or webs of the skin and multiple congenital anomalies. We present a 15-year-old patient with Escobar syndrome who complained of persistent blunt abdominal pain for 1 year. Preoperative evaluation confirmed the diagnosis of imperforate hymen, and the patient underwent hymenectomy under intravenous sedation. the patient's postoperative course was uneventful and her complaints resolved completely. After a 3-month follow-up, she reported having normal menstrual bleeding intervals each month without any complications. Patients with Escobar syndrome may suffer from abdominal pain due to imperforate hymen. Careful evaluation of these patients must include a complete gynaecological assessment and, if indicated, surgical treatment must be performed without delay. (C) 2014 S. Karger AG, Base

Response to: Platelet indices in patients with unexplained recurrent miscarriage; related factors should be considered

WOS: 000340518300006PubMed: 24925348[No abstract available