534 research outputs found
How find (and where) GIS data
These notes are for the sole purpose of describing the GIS data discovery proces
GIS Decalogue
These points would propose how to to a GIS environment. Any suggestion will be appreciated
An open source 'approach' for the MoMoWo GIS database
Starting from an idea of a participatory stream of knowledge, MoMoWo project has represented the field in which try to share information using free and open source software, tools and databases only. This is why we have created a WEBGIS about Women's creativity using LibreOffice, QGIS and qgis2web. In fact, a WEBGIS system is the best way to publish and share knowledge all around the world
Source and Data for the Analysis of the Metropolitan Territory with GIS Tools: A Critical Review Between Commercial and Open Access Tools
This contribution addresses the issue of the availability and accessibility of data for urban and regional studies. After an initial part in which tools and arguments are provided to frame the open data paradigm, the second part proceeds with the simulation of a GIS-based study on a territory of the Metropolitan City of Turin aimed at supporting post-COVID territorial planning, highlighting the areas in which there is a lack of data, the difficulty of access, such as in health care, or the obligation to have to use commercial data. In the last part, the results of the study are discussed, and the issue of the importance of the construction of digital models (digital twins) capable of receiving and processing data of different sources, and how these models should be developed according to an open and non-commercial paradigm
From "Free Information" to Its (Geo)referencing and Analysis: The "Costs" of Open Source
ENG-Is it possible, starting from free data or free information, also available online, to get a representation of them on paper, consequently highlight- ing the real spatial component? How to handle normal address lists and to achieve their transformation into geographic coordinates, expressed in lati- tude and longitude? What difficulties come up against and how can we face and overcome them? This contribution, trying to return an updated image of the current situation, highlights potential and critical points of mecha- nisms and procedures rarely accessible in an effective manner. Finally, it dwells on the opportunities offered by information sharing and knowledge since they facilitate the individual and collective growth, the participatory processes and the social justice. ITA-È possibile, a partire da dati o informazioni libere, disponibili anche in rete, ottenere una loro rappresentazione grafica che ne metta in evidenza la reale dimensione spaziale? Come gestire semplici liste di indirizzi e ottenere la loro trasformazione in coordinate geografiche, espresse in latitudine e longitudine? Quali difficoltà si incontrano e come si possono affrontare e superare? Questo contributo, cercando di offrire un quadro aggiornato della situazione attuale, mette in evidenza le potenzialità e i punti critici di meccanismi e procedure volti a ottenere questi risultati. Infine, vengono sottolineate le opportunità offerte dalla condivisione di informazioni e conoscenze in quanto possono agevolare la crescita individuale e collettiva, i processi di partecipazione e la giustizia social
Expression in Escherichia coli, Functional Characterization, and Tissue Distribution of Isoforms A and B of the Phosphate Carrier from Bovine Mitochondria
The two isoforms of the mammalian mitochondrial phosphate carrier (PiC), A and B, differing in the sequence near the N terminus, arise from alternative splicing of a primary transcript of the PiC gene (Dolce, V., Iacobazzi, V., Palmieri, F., and Walker, J. E. (1994) J. Biol. Chem. 269, 10451-10460). To date, the PiC isoforms A and B have not been studied at the protein level. To explore the tissue-distribution and the potential functional differences between the two isoforms, polyclonal site-directed antibodies specific for PiC-A and PiC-B were raised, and the two bovine isoforms were obtained by expression in Escherichia coli and reconstituted into phospholipid vesicles. Western blot analysis demonstrated that isoform A is present in high amounts in heart, skeletal muscle, and diaphragm mitochondria, whereas isoform B is present in the mitochondria of all tissues examined. Heart and liver bovine mitochondria contained 69 and 0 pmol of PiC-A/mg of protein, and 10 and 8 pmol of PiC-B/mg of protein, respectively. In the reconstituted system the pure recombinant isoforms A and B both catalyzed the two known modes of transport (Pi/Pi antiport and Pi/H+ symport) and exhibited similar properties of substrate specificity and inhibitor sensitivity. However, they strongly differed in their kinetic parameters. The transport affinities of isoform B for phosphate and arsenate were found to be 3-fold lower than those of isoform A. Furthermore, the maximum transport rate of isoform B is about 3-fold higher than that of isoform A. These results support the hypothesis that the sequence divergence between PiC-A and PiC-B may have functional significance in determining the affinity and the translocation rate of the substrate through the PiC molecule
From "Free Information" to Its (Geo)referencing and Analysis: The "Costs" of Open Source
ENG-Is it possible, starting from free data or free information, also available
online, to get a representation of them on paper, consequently highlight-
ing the real spatial component? How to handle normal address lists and to
achieve their transformation into geographic coordinates, expressed in lati-
tude and longitude? What difficulties come up against and how can we face
and overcome them? This contribution, trying to return an updated image
of the current situation, highlights potential and critical points of mecha-
nisms and procedures rarely accessible in an effective manner. Finally, it
dwells on the opportunities offered by information sharing and knowledge
since they facilitate the individual and collective growth, the participatory
processes and the social justice. ITA-È possibile, a partire da dati o informazioni libere, disponibili anche in rete, ottenere una loro rappresentazione grafica che ne metta in evidenza la reale dimensione spaziale? Come gestire semplici liste di indirizzi e ottenere la loro trasformazione in coordinate geografiche, espresse in latitudine e longitudine? Quali difficoltà si incontrano e come si possono affrontare e superare? Questo contributo, cercando di offrire un quadro aggiornato della situazione attuale, mette in evidenza le potenzialità e i punti critici di meccanismi e procedure volti a ottenere questi risultati. Infine, vengono sottolineate le opportunità offerte dalla condivisione di informazioni e conoscenze in quanto possono agevolare la crescita individuale e collettiva, i processi di partecipazione e la giustizia sociale
Anamorphic Cartograms and Environmental Risk Analysis
Both Geography and Statistics use graphical representations. Information Technology has enhanced the visualization of data, beyond the traditional aspects, to such an extent that we can nowadays speak of an “image society”. Traditional thematic mapping also shows transformations of a variable over time, linking the geographical datum to the time variable. For some decades now a number of cartograms have been in use, for which the base area is displaced as a function of a particular factor, these are known as anamorphic cartograms. An anamorphic map is easier to read and may give an overview of a geographic whole
Mitochondrial transport and metabolism of the vitamin B-derived cofactors thiamine pyrophosphate, coenzyme A, FAD and NAD+, and related diseases: A review
Multiple mitochondrial matrix enzymes playing key roles in metabolism require cofactors for their action. Due to the high impermeability of the mitochondrial inner membrane, these cofactors need to be synthesized within the mitochondria or be imported, themselves or one of their precursors, into the organelles. Transporters belonging to the protein family of mitochondrial carriers have been identified to transport the coenzymes: thiamine pyrophosphate, coenzyme A, FAD and NAD+, which are all structurally similar to nucleotides and derived from different B-vitamins. These mitochondrial cofactors bind more or less tightly to their enzymes and, after having been involved in a specific reaction step, are regenerated, spontaneously or by other enzymes, to return to their active form, ready for the next catalysis round. Disease-causing mutations in the mitochondrial cofactor carrier genes compromise not only the transport reaction but also the activity of all mitochondrial enzymes using that particular cofactor and the metabolic pathways in which the cofactor-dependent enzymes are involved. The mitochondrial transport, metabolism and diseases of the cofactors thiamine pyrophosphate, coenzyme A, FAD and NAD+ are the focus of this review
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