Experimental evidence for radiative attachment in astrochemistry from electron attachment to NCCCCN

Electron attachment to NCCCCN, dicyanoacetylene (2-butynedinitrile), has been observed. Metastable parent anions, NCCCCN_∗, with microsecond or longer lifetimes are formed close to 0 eV electron energy with a cross section of ≥0.25 2. The stability of NCCCCN suggests that radiative attachment to NCCCCN and similar _∗ °A linear carbon chain molecules may be an important mechanism for the formation of negatively charged molecular ions in astrophysical environments. CCCN_ and CN_ fragment anions are formed at ∼3 and ∼6 eV

ARE CROP YIELDS NORMALLY DISTRIBUTED?

This paper revisits the issue of crop yield distributions using improved model specifications, estimation and testing procedures that address the methodological concerns raised in recent literature that could have invalidated previous conclusions of yield non-normality. It shows beyond reasonable doubt that some crop yield distributions are non-normal, kurtotic and right or left skewed, depending on the circumstances. A procedure to jointly estimate non-normal farm- and aggregate-level yield distributions with similar means but different variances is illustrated, and the consequences of incorrectly assuming yield normality are explored.Yield non-normality, probability distribution function models, Corn Belt yields, West Texas dryland cotton yields, Crop Production/Industries,

Final state interactions and hadron quenching in cold nuclear matter

I examine the role of final state interactions in cold nuclear matter in modifying hadron production on nuclear targets with leptonic or hadronic beams. I demonstrate the extent to which available experimental data in electron-nucleus collisions can give direct information on final state effects in hadron-nucleus and nucleus-nucleus collisions. For hadron-nucleus collisions, a theoretical estimate based on a parton energy loss model tested in lepton-nucleus collisions shows a large effect on mid-rapidity hadrons at fixed target experiments. At RHIC energy, the effect is large for negative rapidity hadrons, but mild at midrapidity. This final state cold hadron quenching needs to be taken into account in jet tomographic analysis of the medium created in nucleus-nucleus collisions.Comment: 14 pages, 7 figure

Roflumilast: first phosphodiesterase 4 inhibitor approved for treatment of COPD

In April 2010, the European Medicines Agency Committee for Medicinal Products for Human Use recommended approval of roflumilast, a selective phosphodiesterase 4 inhibitor, for the “maintenance treatment of severe chronic obstructive pulmonary disease (COPD, FEV1 postbronchodilator less than 50% predicted) associated with chronic bronchitis in adult patients with a history of frequent exacerbations as add-on to bronchodilator treatment”. This decision was based, in part, on the results of several large, international, multicenter, randomized, placebo-controlled trials of either six or 12 months’ duration that had been undertaken in COPD patients. Roflumilast 500 μg daily improved lung function and reduced exacerbations in patients with more severe COPD, especially those with chronic bronchitis, frequent exacerbations, or who required frequent rescue inhaler therapy in the placebo-controlled trials. It also improved lung function and reduced exacerbations in patients with moderately severe COPD treated with salmeterol or tiotropium. Advantages of roflumilast over inhaler therapy are that it is an oral tablet and only needs to be taken once daily. While taking roflumilast, the most common adverse effects patients experienced were gastrointestinal upset and headache. Weight loss, averaging 2.2 kg, occurred in patients treated with roflumilast. Patients taking roflumilast were more likely to drop out of the trials than patients in the control groups. Patients who discontinued therapy usually did so during the first few weeks and were more likely to have experienced gastrointestinal side effects. Roflumilast is the first selective phosphodiesterase 4 inhibitor and will offer physicians another treatment option for patients with more severe COPD

Cosmological Magnetic Fields from Primordial Helicity

Primordial magnetic fields may account for all or part of the fields observed in galaxies. We consider the evolution of the magnetic fields created by pseudoscalar effects in the early universe. Such processes can create force-free fields of maximal helicity; we show that for such a field magnetic energy inverse cascades to larger scales than it would have solely by flux freezing and cosmic expansion. For fields generated at the electroweak phase transition, we find that the predicted wavelength today can in principle be as large as 10 kpc, and the field strength can be as large as 10^{-10} G.Comment: 13 page

Repository as a Service (RaaS)

In his oft-quoted seminal paper ‘Institutional Repositories: Essential Infrastructure For Scholarship In The Digital Age’ Clifford Lynch (2003) described the Institutional Repository as “a set of services that a university offers to the members of its community for the management and dissemination of digital materials created by the institution and its community members.” This paper seeks instead to define the repository service at a more primitive level, without the specialism of being an ‘Institutional Repository’, and looks at how it can viewed as providing a service within appropriate boundaries, and what that could mean for the future development of repositories, our expectations of what repositories should be, and how they could fit into the set of services required to deliver an Institutional Repository service as describe by Lynch