Computational sequence analysis of a plastid-localized enzyme in plants

1-deoxy-D-xylulose-5 phosphate synthase (DXPS), a key regulatory enzyme in the nonmevalonate branch of the terpenoid biosynthetic pathway, is located in plastids. Sequence analysis of the DXPS and DXPS-like genes and signal sequences from multiple plant species included primary structure sequence alignments, common secondary structure features, and predicted hydrophobicity regions. The functional protein was found to be highly conserved, however the inferred gene trees did not resemble classical species trees. Although conservation of the signal sequence was not significant, there was similarity between hydrophobicity plots

Discontinuation of clonazepam in the treatment of social phobia

Connor, Kathryn M.; Davidson, Jonathan R. T.; Potts, Nicholas L. S.; Tupler, Larry A.; Miner, Cherri M.; Malik, Mary L.; Book, Sarah W.; Colket, Jeffrey T.; Ferrell, Fa