Dynamical and radiative properties of astrophysical supersonic jets I. Cocoon morphologies

We present the results of a numerical analysis of the propagation and interaction of a supersonic jet with the external medium. We discuss the motion of the head of the jet into the ambient in different physical conditions, carrying out calculations with different Mach numbers and density ratios of the jet to the exteriors. Performing the calculation in a reference frame in motion with the jet head, we can follow in detail its long term dynamics. This numerical scheme allows us also to study the morphology of the cocoon for different physical parameters. We find that the propagation velocity of the jet head into the ambient medium strongly influences the morphology of the cocoon, and this result can be relevant in connection to the origin and structure of lobes in extragalactic radiosources.Comment: 14 pages, TeX. Accepted for A&

A new approach to the study of quasi-normal modes of rotating stars

We propose a new method to study the quasi-normal modes of rotating relativistic stars. Oscillations are treated as perturbations in the frequency domain of the stationary, axisymmetric background describing a rotating star. The perturbed quantities are expanded in circular harmonics, and the resulting 2D-equations they satisfy are integrated using spectral methods in the (r,theta)-plane. The asymptotic conditions at infinity, needed to find the mode frequencies, are implemented by generalizing the standing wave boundary condition commonly used in the non rotating case. As a test, the method is applied to find the quasi-normal mode frequencies of a slowly rotating star.Comment: 24 pages, 7 figures, submitted to Phys. Rev.

Raman Fingerprint of Charged Impurities in Graphene

We report strong variations in the Raman spectra for different single-layer graphene samples obtained by micromechanical cleavage, which reveals the presence of excess charges, even in the absence of intentional doping. Doping concentrations up to ~10^13 cm-2 are estimated from the G peak shift and width, and the variation of both position and relative intensity of the second order 2D peak. Asymmetric G peaks indicate charge inhomogeneity on the scale of less than 1 micron.Comment: 3 pages, 5 figure

Distributed bounded-error state estimation for partitioned systems based on practical robust positive invariance

We propose a partition-based state estimator for linear discrete-time systems composed by coupled subsystems affected by bounded disturbances. The architecture is distributed in the sense that each subsystem is equipped with a local state estimator that exploits suitable pieces of information from parent subsystems. Moreover, differently from methods based on moving horizon estimation, our approach does not require the on-line solution to optimization problems. Our state-estimation scheme, that is based on the notion of practical robust positive invariance developed in Rakovic 2011, also guarantees satisfaction of constraints on local estimation errors and it can be updated with a limited computational effort when subsystems are added or removed

Two distinct desynchronization processes caused by lesions in globally coupled neurons

To accomplish a task, the brain works like a synchronized neuronal network where all the involved neurons work together. When a lesion spreads in the brain, depending on its evolution, it can reach a significant portion of relevant area. As a consequence, a phase transition might occur: the neurons desynchronize and cannot perform a certain task anymore. Lesions are responsible for either disrupting the neuronal connections or, in some cases, for killing the neuron. In this work, we will use a simplified model of neuronal network to show that these two types of lesions cause different types of desynchronization.Comment: 5 pages, 3 figure

Erratum to: Do RANKL inhibitors (denosumab) affect inflammation and immunity?

Receptor activator of nuclear factor kappa B ligand (RANKL) and its natural antagonist, osteoprotegerin (OPG), are, respectively, an indispensable factor and a potent inhibitor for osteoclast differentiation, activity, and survival. The development of a human monoclonal antibody to RANKL, denosumab, constitutes a novel approach to prevent fragility fractures in osteoporosis, skeletal complications of malignancy, and potentially bone erosions in rheumatoid arthritis (RA). In addition to being expressed by osteoblasts, RANKL is abundantly produced by activated T cells, and synoviocytes in RA, whereas its receptor, RANK, is also expressed by monocytes/macrophages and dendritic cells. However, in preclinical and clinical studies of RA—including patients with some degree of immunosuppression—RANKL inhibitors did not significantly alter inflammatory processes. RANKL, RANK, and OPG deficiency in murine models highlights the important role of this pathway in the development and maturation of the immune system in rodents, including functions of T and/or B cells, whereas OPG overexpression in mice and rats seems innocuous with regard to immunity. In contrast, loss-of-function mutations in humans have more limited effects on immune cells. In clinical studies, the overall rate of infections, cancer, and death was similar with denosumab and placebo. Nevertheless, the risk of severe infections and cancer in some specific tissues remains to be carefully scrutinize

Investment and Usage of New Technologies: Evidence from a Shared ATM Network

When new technologies become available, it is not only essential that firms have the correct investment incentives, but often also that consumers make the proper usage decisions. This paper studies investment and usage in a shared ATM network. Be- cause all banks coordinate their ATM investment decisions, there is no strategic but only a pure cost-saving incentive to invest. At the same time, because retail fees for cash withdrawals are regulated to zero at both branches and ATMs, consumers may not have the proper incentives to substitute their transactions from branches to the available ATMs. We develop an empirical model of coordinated investment and cash withdrawal demand, where banks choose the number of ATMs and consumers decide whether to withdraw cash at ATMs or branches. We find that banks substantially underinvested in the shared ATM network and thus provided too little geographic coverage. This contrasts with earlier findings of strategic overinvestment in networks with partial incompatibility. Furthermore, we find that consumer usage of the avail- able ATM network is too low because of the zero retail fees for cash withdrawals at branches. A direct promotion of investment (through subsidies or other means) can improve welfare, but the introduction of retail fees on cash withdrawals at branches would be more e¤ective, even if this does not encourage investment per se.