Southern Area of the Greek Agora in Kos. Archaeological park project.

The project, included in a degree thesis held at the Polytechnic of Bari, is a plan for an archaeological park set in the area of the Hellenistic agora of Kos (Greece). The proposal is based on a preliminary historical research, in these years carried out by prof. G. Rocco e M. Livadiotti, focused on the reconstruction of the ancient form of the large agora (IV-II cent. B.C.). The study analyses the remains of building structures and architectural fragments discovered in six different diggings. Our project goals are: 1) to allow visitors to understand the original plan of the city, although the deep contrast with the current urban tissue; 2) to redevelop the six archaeological sites analysed in order to make the remains of the ancient agora accessible to the public and, moreover, to allow to consider them as elements of a single monument. The planning is developed at urban scale and involves enlargement and redefinition of the excavated portions, creation of accesses and footbridges and eventually anastylosis in situ of some remains. Other relevant features of the project are: 1) the building of retaining walls made of concrete covered with a earth mixture which makes wall surface similar to the ground; 2) the insertion of 246-2 vegetation in some specific areas which, on one hand, functions as enclosure and visual barrier to modern city and, on the other, it works as instrument to highlight the most important streets of the ancient city. Since it’s not allowed to build in archaeological sites, it’s chosen to use green-system to configure three dimensional space. Therefore, control and knowledge of the specific form of woody species play an important role in the project

Focus on therapy of hypnic headache

Hypnic headache (HH) is a primary headache disorder, which occurs exclusively during sleep and usually begins after 50 years of age. There are no controlled trials for the treatment of HH. We reviewed all the available papers, including 119 cases published in literature up to date, reporting the efficacy of the medications used to treat HH. Acute treatment is not recommended, since no drug proved to be clearly effective and also because the intensity and the duration of the attacks do not require the intake of a medication in most cases. As for prevention, a wide variety of medications were reported to be of benefit in HH. The drugs that were found to be effective in at least five cases are: lithium, indomethacin, caffeine and flunarizine. Lithium was the most extensively studied compound and demonstrated to be an efficacious treatment in 32 cases. Unfortunately, despite its efficacy, significant adverse effects and poor tolerability are not rare, mainly in elderly patients. Many patients reported a good response to indomethacin, but some could not tolerate it. Caffeine and melatonin treatments did not yield robust evidence to recommend their use as single preventive agents. Nevertheless, their association with lithium or indomethacin seems to produce an additional therapeutic efficacy. A course of lithium should be tried first, followed 3–4 months later by tapering. If headache recurs during tapering, a longer duration of therapy may be needed. If lithium treatment does not provide a significant response, indomethacin can be commenced as second-line approach. If these treatments prove to be ineffective or poorly tolerated, other agents, such as caffeine and melatonin, can be administered

'Rocha' pear mineral composition relation with quality traits

info:eu-repo/semantics/publishedVersio

Effect of naphthaleneacetic acid on restoring ‘Rocha’ pear ripening under 1-MCP evergreen effect

info:eu-repo/semantics/publishedVersio

FreeBirds leaflet - Introduction to the project

Italian version of the FreeBirds leaflet (Core Organic Cofund) - Introduction to the projec

Effect of naphthaleneacetic acid on restoring ‘Rocha’ pear ripening under 1-MCP evergreen effect

'Rocha’ pear (Pyrus communis L. cv. Rocha), a DOP cultivar from the west region of Portugal, is quite appreciated worldwide due to its exceptional organoleptic quality. Because of its high exportation, preservation of this cultivar during long-term cold storage is of utmost importance, but remains a challenge for suppliers, especially after diphenylamine exclusion from the agricultural sector. Since then, postharvest disorders have been prevented through the use of 1-methylcyclopropene (1-MCP). Nevertheless, this compound disrupts the normal ripening of fruit, affecting its eating quality and producer’s sustainability. Consequently, there is the need for developing innovative solutions to recover ‘Rocha’ pear ripening capacity after 1-MCP application. Several strategies have been investigated to avoid the persistent blockage of ripening after 1-MCP as, for example, the application exogenous ethylene, the increase of temperature, but demand high energy consumption. This study was designed to test the restorage of ripening via immersion of 1-MCP treated fruits in an auxin- 1-Naphthaleneacetic acid (1-NAA) solution. Fruit ripening as judged by ethylene evolution and respiration associated with color changes and softening, was accelerated by 1-NAA treatment compared to control (pear only treated with 1-MCP). 1-NAA treatment effect was evident through the firmness loss of the fruit (ca. 60%) and increased internal ethylene production (ca. 50%). Also, exogenous 1-NAA treatment increased 1-aminocyclopropane carboxylic acid and ACC oxidase activity corroborating the physiological results obtained. The results provide information regarding how 1-MCP blockage may be circumvented, thus opening avenues for consistent ripening of ‘Rocha’ pear ensuring fruit quality and reducing postharvest losses.info:eu-repo/semantics/publishedVersio

'Rocha’ Pear ripening under the 1-mcp evergreen effect: the impact of the auxin 1-naphthaleneacetic acid treatment

‘Rocha’ pear (Pyrus communis L. cv. Rocha), is a DOP cultivar from the West region of Portugal that is appreciated worldwide. Combined with controlled atmosphere storage, 1-methylcyclopropene (1-MCP) application, an antagonist of ethylene action, has been one of the most applied techniques to extend the storage of ‘Rocha’ pear. However, fruit industry is facing a problem resulting from 1-MCP application: it prevents the normal ripening of the fruit and affects the final quality at the consumer level. In this study, we exposed 1-MCP treated fruits to an auxin 1-naphthaleneacetic acid (1- NAA) solution (2 mM) and analyzed the efficacy in restoring the ripening of ‘Rocha’ pear. First, during the first 24 h, we determined the primary impact of 1-NAA on the expression of genes encoding ethylene receptors (PcETRs) and ethylene biosynthesis enzymes (PcACS and PcACO), combined with lipid peroxidation and reactive oxygen species. We also studied the effect of 1-NAA on ethylene production, respiration, and other ripening markers (firmness and sugars) across shelf life. Herein, the expression of PcACS1 and PcACS4 increased in 1-MCP fruit treated with 1- NAA compared to pear treated only with 1-MCP. Additionally, the expression of PcETR2 and PcETR5 was enhanced, revealing the potential of the 1-NAA treatment in inducing the production of new ethylene receptors. Time course physicochemical analysis revealed that fruit ripening was accelerated by 1- NAA treatment, as judged by ethylene evolution and respiration associated with softening. The 1-NAA treatment increased firmness loss (ca. 60%) and internal ethylene production (ca. 50%). Also, exogenous 1-NAA treatment increased 1- aminocyclopropane carboxylic acid (ca. 28%) and ACC oxidase activity (ca. 15%) corroborating the increased in gene expression. Our findings reveal that 1-NAA treatment may circumvent 1-MCP effect providing valuable information for ripening studies in pear.info:eu-repo/semantics/publishedVersio

The effect of temperature and exogenous ethylene on the ripening of ‘Rocha’ pear pretreated with 1-MCP

info:eu-repo/semantics/publishedVersio