3 research outputs found
Effects of masticatory hypofunction on mandibular morphology, mineral density and basal bone area
Aim: This experimental study investigated the association between
masticatory hypofunction and mandibular morphological dimensions and
internal bone characteristics. Methods: Twentyfour 21-day-old male
Wistar rats were randomly divided into two groups, according to the
diet consistency. The control group (CG) was fed a solid diet (pellets)
and the experimental group (EG) received a powdered diet during 50
days. All animals were euthanized and their mandibles removed and
processed for histomorphometric analysis. A calibrated examiner
performed linear and angular measurements (mandibular body length and
height, mandibular lengths, ramus depth and height, mandibular base
depth, mandibular head and gonial angle) on photographs, estimated bone
density in the mandibular ramus region on digital radiographs and
assessed the area of cortical and trabecular bone tissue in the second
molar region, in 5-μm-thick serial cuts stained with Cason’s
Trichrome. Measurements for the study groups were compared using
Mann-Whitney test (α=0.05). Results: some of the macroscopic
dimensions evaluated on photographs were significantly smaller in EG
compared to CG, specifically mandibular ramus height (10.77 mm vs.
11.11 mm, p=0.0375), mandibular body length (21.67 mm vs. 22.36 mm,
p=0.0165) and height (4.24 mm vs. 4.54 mm, p=0.0016), as well as
mandibular base depth (1.24 mm vs. 1.47 mm, p=0.0325). The relative
mineral bone density was significantly decreased in EG (1.04) compared
to CG (1.25), p<0.001. Rats in the EG also presented smaller
trabecular and cortical bone area (2.36 mm²) than those in CG
(3.16 mm²), p<0.001. Conclusions: Based on the above-mentioned
measurements, it may be concluded that masticatory hypofunction induced
by a powdered diet affected mandibular morphology and was associated
with significantly reduced bone content
Effects of masticatory hypofunction on mandibular morphology, mineral density and basal bone area
AIM: This experimental study investigated the association between masticatory hypofunction and mandibular morphological dimensions and internal bone characteristics. METHODS: Twentyfour 21-day-old male Wistar rats were randomly divided into two groups, according to the diet consistency. The control group (CG) was fed a solid diet (pellets) and the experimental group (EG) received a powdered diet during 50 days. All animals were euthanized and their mandibles removed and processed for histomorphometric analysis. A calibrated examiner performed linear and angular measurements (mandibular body length and height, mandibular lengths, ramus depth and height, mandibular base depth, mandibular head and gonial angle) on photographs, estimated bone density in the mandibular ramus region on digital radiographs and assessed the area of cortical and trabecular bone tissue in the second molar region, in 5-µm-thick serial cuts stained with Cason's Trichrome. Measurements for the study groups were compared using Mann-Whitney test (α=0.05). larvae to induce experimental candidiasis, and after 24 hours, the survival rate was assessed. RESULTS: some of the macroscopic dimensions evaluated on photographs were significantly smaller in EG compared to CG, specifically mandibular ramus height (10.77 mm vs. 11.11 mm, p=0.0375), mandibular body length (21.67 mm vs. 22.36 mm, p=0.0165) and height (4.24 mm vs. 4.54 mm, p=0.0016), as well as mandibular base depth (1.24 mm vs. 1.47 mm, p=0.0325). The relative mineral bone density was significantly decreased in EG (1.04) compared to CG (1.25), p<0.001. Rats in the EG also presented smaller trabecular and cortical bone area (2.36 mm²) than those in CG (3.16 mm²), p<0.001. CONCLUSIONS: Based on the above-mentioned measurements, it may be concluded that masticatory hypofunction induced by a powdered diet affected mandibular morphology and was associated with significantly reduced bone content
Effects of masticatory hypofunction on mandibular morphology, mineral density and basal bone area
is experimental study investigated the association between masticatory hypofunction and mandibular morphological dimensions and internal bone characteristics. Methods: Twentyfour 21-day-old male Wistar rats were randomly divided into two groups, according to the diet consistency. The control group (CG) was fed a solid diet (pellets) and the experimental group (EG) received a powdered diet during 50 days. All animals were euthanized and their mandibles removed and processed for histomorphometric analysis. A calibrated examiner performed linear and angular measurements (mandibular body length and height, mandibular lengths, ramus depth and height, mandibular base depth, mandibular head and gonial angle) on photographs, estimated bone density in the mandibular ramus region on digital radiographs and assessed the area of cortical and trabecular bone tissue in the second molar region, in 5-µm-thick serial cuts stained with Casons Trichrome. Measurements for the study groups were compared using Mann-Whitney test (α=0.05). Results: some of the macroscopic dimensions evaluated on photographs were significantly smaller in EG compared to CG, specifically mandibular ramus height (10.77 mm vs. 11.11 mm, p=0.0375), mandibular body length (21.67 mm vs. 22.36 mm, p=0.0165) and height (4.24 mm vs. 4.54 mm, p=0.0016), as well as mandibular base depth (1.24 mm vs. 1.47 mm, p=0.0325). The relative mineral bone density was significantly decreased in EG (1.04) compared to CG (1.25), p<0.001. Rats in the EG also presented smaller trabecular and cortical bone area (2.36 mm²) than those in CG (3.16 mm²), p<0.001. Conclusions: Based on the above-mentioned measurements, it may be concluded that masticatory hypofunction induced by a powdered diet affected mandibular morphology and was associated with significantly reduced bone content