Multidisciplinary Prehabilitation and Postoperative Rehabilitation for Avoiding Complications in Patients Undergoing Resection of Colon Cancer: Rationale, Design, and Methodology of the ONCOFIT Study

Funding: This study was funded by the University of Granada, Plan Propio de Investigación 2016- Excellence actions: Unit of Excellence on Exercise and Health (UCEES). P.C. was supported by the Margarita Salas postdoctoral grant, convened by de University of the Basque Country (UPV/EHU), funded by the Ministry of Universities of Spain and the European Union-Next Generation EU.ONCOFIT is a randomized clinical trial with a two-arm parallel design aimed at determining the influence of a multidisciplinary Prehabilitation and Postoperative Program (PPP) on post-surgery complications in patients undergoing resection of colon cancer. This intervention will include supervised physical exercise, dietary behavior change, and psychological support comparing its influence to the standard care. Primary and secondary endpoints will be assessed at baseline, at preoperative conditions, at the end of the PPP intervention (after 12 weeks) and 1-year post-surgery, and will include: post-surgery complications (primary endpoint); prolonged hospital length of stay; readmissions and emergency department call within 1-year after surgery; functional capacity; patient reported outcome measures targeted; anthropometry and body composition; clinical/tumor parameters; physical activity levels and sedentariness; dietary habits; other unhealthy habits; sleep quality; and fecal microbiota diversity and composition. Considering the feasibility of the present intervention in a real-life scenario, ONCOFIT will contribute to the standardization of a cost-effective strategy for preventing and improving health-related consequences in patients undergoing resection of colon cancer with an important clinical and economic impact, not only in the scientific community, but also in clinical practice.University of Granada, Plan Propio de Investigación 2016- Excellence actions: Unit of Excellence on Exercise and Health (UCEES)Margarita Salas postdoctoral grant, convened by de University of the Basque Country (UPV/EHU), funded by the Ministry of Universities of Spain and the European Union-Next Generation E

Multidisciplinary Prehabilitation and Postoperative Rehabilitation for Avoiding Complications in Patients Undergoing Resection of Colon Cancer: Rationale, Design, and Methodology of the ONCOFIT Study

ONCOFIT is a randomized clinical trial with a two-arm parallel design aimed at determining the influence of a multidisciplinary Prehabilitation and Postoperative Program (PPP) on post-surgery complications in patients undergoing resection of colon cancer. This intervention will include supervised physical exercise, dietary behavior change, and psychological support comparing its influence to the standard care. Primary and secondary endpoints will be assessed at baseline, at preoperative conditions, at the end of the PPP intervention (after 12 weeks) and 1-year post-surgery, and will include: post-surgery complications (primary endpoint); prolonged hospital length of stay; readmissions and emergency department call within 1-year after surgery; functional capacity; patient reported outcome measures targeted; anthropometry and body composition; clinical/tumor parameters; physical activity levels and sedentariness; dietary habits; other unhealthy habits; sleep quality; and fecal microbiota diversity and composition. Considering the feasibility of the present intervention in a real-life scenario, ONCOFIT will contribute to the standardization of a cost-effective strategy for preventing and improving health-related consequences in patients undergoing resection of colon cancer with an important clinical and economic impact, not only in the scientific community, but also in clinical practice.This study was funded by the University of Granada, Plan Propio de Investigación 2016-Excellence actions: Unit of Excellence on Exercise and Health (UCEES). P.C. was supported by the Margarita Salas postdoctoral grant, convened by de University of the Basque Country (UPV/EHU), funded by the Ministry of Universities of Spain and the European Union-Next Generation EU

Beneficios del ejercicio físico sobre la presión arterial en adultos mayores con hipertensión: Programa de intervención BET ON YOUR HEALTH.

El presente trabajo está enfocado en las personas mayores con hipertensión, y cómo las mismas podrían verse beneficiadas por la realización de ejercicio físico. En primer lugar, se establece una pequeña contextualización sobre la enfermedad. Qué significa padecer la misma, causas relacionadas con la aparición, síntomas asociados, prevalencia de la enfermedad y posibles tratamientos. Posteriormente, en los siguientes apartados, se exponen el conjunto de beneficios que obtendría una persona mayor con hipertensión con la realización de ejercicio. En los mismos, se establecen cuáles parecen ser las variables de entrenamiento (criterios TIFD-P) más eficientes para el tratamiento de la enfermedad, lo que sustentará el posterior programa “Bet on your Health”. El último punto del trabajo, está destinado al desarrollo de este programa de intervención, exponiendo todas las fases que componen el mismo y cómo se desarrollaría cada una de ellas.This paper focuses on older people with hypertension, and how they might benefit from physical exercise. Firstly, a brief contextualisation of the disease is given. What it means to suffer from it, causes related to its onset, associated symptoms, prevalence of the disease and possible treatments. Subsequently, in the following sections, the set of benefits that an older person with hypertension would obtain by taking exercise are set out. These sections establish which training variables (TYHP criteria) appear to be the most efficient for the treatment of the disease, which will underpin the subsequent "Bet on your Health" programme. The last point of the work is devoted to the development of this intervention programme, setting out all the phases that make it up and how each one of them would be developed