Diseases Of Turkeys

During the past decade, the turkey industry has become an important branch of the livestock industry. The number of turkeys raised in the United States during 1945 was approximately 45,000,000 and the crop in 1946 will be almost as large. When this number is compared with the number of turkeys (3,000,000) raised in the United States in 1920, the increase is phenomenal. The turkey industry has grown from a minor farm enterprise to big business. A few years ago the average size flock was a few hundred. Now it is not uncommon to see flocks of several thousand. During the past year Iowa raised as many turkeys as the entire United States produced in 1920

DIII-D research advancing the physics basis for optimizing the tokamak approach to fusion energy

Publicación con muchos autores, entre ellos la investigadora de la Universidad de Sevilla: Cano Megías, PilarDIII-D physics research addresses critical challenges for the operation of ITER and the next generation of fusion energy devices. This is done through a focus on innovations to provide solutions for high performance long pulse operation, coupled with fundamental plasma physics understanding and model validation, to drive scenario development by integrating high performance core and boundary plasmas. Substantial increases in off-axis current drive efficiency from an innovative top launch system for EC power, and in pressure broadening for Alfven eigenmode control from a co-/counter-Ip steerable off-axis neutral beam, all improve the prospects for optimization of future long pulse/steady state high performance tokamak operation. Fundamental studies into the modes that drive the evolution of the pedestal pressure profile and electron vs ion heat flux validate predictive models of pedestal recovery after ELMs. Understanding the physics mechanisms of ELM control and density pumpout by 3D magnetic perturbation fields leads to confident predictions for ITER and future devices. Validated modeling of high-Z shattered pellet injection for disruption mitigation, runaway electron dissipation, and techniques for disruption prediction and avoidance including machine learning, give confidence in handling disruptivity for future devices. For the non-nuclear phase of ITER, two actuators are identified to lower the L–H threshold power in hydrogen plasmas. With this physics understanding and suite of capabilities, a high poloidal beta optimized-core scenario with an internal transport barrier that projects nearly to Q = 10 in ITER at ∼8 MA was coupled to a detached divertor, and a near super H-mode optimized-pedestal scenario with co-Ip beam injection was coupled to a radiative divertor. The hybrid core scenario was achieved directly, without the need for anomalous current diffusion, using off-axis current drive actuators. Also, a controller to assess proximity to stability limits and regulate βN in the ITER baseline scenario, based on plasma response to probing 3D fields, was demonstrated. Finally, innovative tokamak operation using a negative triangularity shape showed many attractive features for future pilot plant operation.US Department of Energy - Office of Science - Office of Fusion Energy Sciences DE-FC02- 04ER54698 y DE-AC52-07NA2734

Mathematical Model and Analysis of Drug Addiction among Adolescent’s Populace in Nigeria

Drug addiction has become a menace especially among adolescents which has massively contributed to the social vices perpetrated by youths in Nigeria. We constructed a five-compartment model to explain the transmission dynamics of addiction leading to a non-linear deterministic equation. The next generation approach was employed to obtain the basic reproduction number (R_0). The drug free equilibrium point was obtained and showed to be locally asymptotically stable when the threshold quantity is less than one. A suitable Lyapunov function was constructed for the global stability which was found to be globally asymptotically stable. Sensitivity analysis was conducted to ascertain the behavior of the various parameters on the threshold quantity to deduce a suitable intervention strategy. Numerical simulations are carried out, the analysis is discussed, and the results are presented in graphical form. Keywords: Addiction, model, drug, stability, basic reproduction number, sensitivity analysis

In normal rat, intraventricularly administered insulin-like growth factor-1 is rapidly cleared from CSF with limited distribution into brain

BACKGROUND: Putatively active drugs are often intraventricularly administered to gain direct access to brain and circumvent the blood-brain barrier. A few studies on the normal central nervous system (CNS) have shown, however, that the distribution of materials after intraventricular injections is much more limited than presumed and their exit from cerebrospinal fluid (CSF) is more rapid than generally believed. In this study, we report the intracranial distribution and the clearance from CSF and adjacent CNS tissue of radiolabeled insulin-like growth factor-1 after injection into one lateral ventricle of the normal rat brain. METHODS: Under barbiturate anesthesia, (125)I-labeled insulin-like growth factor-1 (IGF-1) was injected into one lateral ventricle of normal Sprague-Dawley rats. The subsequent distribution of IGF-1 through the cerebrospinal fluid (CSF) system and into brain, cerebral blood vessels, and systemic blood was measured over time by gamma counting and quantitative autoradiography (QAR). RESULTS: Within 5 min of infusion, IGF-1 had spread from the infused lateral ventricle into and through the third and fourth ventricles. At this time, 25% of the infused IGF-1 had disappeared from the CSF-brain-meningeal system; the half time of this loss was 12 min. The plasma concentration of cleared IGF-1 was, however, very low from 2 to 9 min and only began to rise markedly after 20 min. This delay between loss and gain plus the lack of radiotracer in the cortical subarachnoid space suggested that much of the IGF-1 was cleared into blood via the cranial and/or spinal nerve roots and their associated lymphatic systems rather than periventricular tissue and arachnoid villi. Less than 10% of the injected radioactivity remained in the CSF-brain system after 180 min. The CSF and arteries and arterioles within the subarachnoid cisterns were labeled with IGF-1 within 10 min. Between 60 and 180 min, most of the radioactivity within the cranium was retained within and around these blood vessels and by periaqueductal gray matter. Tissue profiles at two sites next to ventricular CSF showed that IGF-1 penetrated less than 1.25 mm into brain tissue and appreciable (125)I-activity remained at the tissue-ventricular CSF interface after 180 min. CONCLUSION: Our findings suggest that entry of IGF-1 into normal brain parenchyma after lateral ventricle administration is limited by rapid clearance from CSF and brain and slow movement, apparently by diffusion, into the periventricular tissue. Various growth factors and other neuroactive agents have been reported to be neuroprotective within the injured brain after intraventricular administration. It is postulated that the delivery of such factors to neurons and glia in the injured brain may be facilitated by abnormal CSF flow. These several observations suggest that the flow of CSF and entrained solutes may differ considerably between normal and abnormal brain and even among various neuropathologies

Evolution of 2D deuterium and impurity radiation profiles during transitions from attached to detached divertor operation in DIII-D

This paper presents the detailed evolution of conditions along both the inner and outer divertor legs during the transition from attached ELMing H-mode to partially detached divertor (PDD) operation in DIII-D. Visible emission profiles in a poloidal plane show that in ELMing H-mode prior to deuterium gas injection, CIII emission peaks in the inner SOL near the X-point and deuterium emission (from ionization and recombination) peaks at the inner target plate near the inner strike point (ISP). The spatial profiles of the recombination and ionization zones, determined by forming images of the ratio of intensities from simultaneous images of D{sub {alpha}} and D{sub {gamma}} emission, show that recombination dominates the inner leg emission near the target; ionization dominates in a poloidally narrow zone upstream in the inner leg. After deuterium injection, when the PDD transition begins, the profiles of carbon visible emission show first an increase in the inner SOL near the X-point, followed by increases in emission in the lower regions of the outer leg. Deuterium emission at the transition onset decreases at th4e ISP and increases across the private flux region below the X-point. As the transition to PDD conditions proceeds the deuterium emission increases in the private flux region; recombination dominates near the floor and ionization higher near the X-point. Carbon emission appears along both divertor legs and at the X-point. In the final quasi-steady PDD state, the recombination emission in the outer leg is near the separatrix and along the target plate; emission from collisional excitation dominates in the upper part of the outer leg just below the X-point, and carbon emission is localized at the X-point. These results suggest that transport of neutral deuterium between the inner and outer divertor legs through the private flux region plays an important role in the initiation of outer leg detachment in DIII-D

Supervision and Scholarly Writing: Writing to Learn - Learning to Write

This paper describes an action research project on postgraduate students’ scholarly writing in which I employed reflective approaches to examine and enhance my postgraduate supervisory practice. My reflections on three distinct cycles of supervision illustrate a shift in thinking about scholarly writing and an evolving understanding of how to support postgraduate students’ writing. These understandings provide the foundation for a future-oriented fourth cycle of supervisory practice, which is characterised by three principles, namely the empowerment of students as writers, the technological context of contemporary writing, and ethical issues in writing

Doppler coherence imaging and tomography of flows in tokamak plasmas

This article describes the results of spatial heterodyne Doppler "coherence imaging" of carbon ion flows in the divertor region of the DIII-D tokamak. Spatially encoded interferometric projections of doubly ionized carbon emission at 465 nm have been demodulated and tomographically inverted to obtain the spatial distribution of the carbon ion parallel flow and emissivity. The operating principles of the new instruments are described, and the link between measured properties and line integrals of the flow field are established. An iterative simultaneous arithmetic reconstruction procedure is applied to invert the interferometric phase shift projections, and the reconstructed parallel flow field amplitudes are found to be in reasonable agreement with UEDGE modeling

How are "teaching the teachers" courses in evidence based medicine evaluated? A systematic review

Background Teaching of evidence-based medicine (EBM) has become widespread in medical education. Teaching the teachers (TTT) courses address the increased teaching demand and the need to improve effectiveness of EBM teaching. We conducted a systematic review of assessment tools for EBM TTT courses. To summarise and appraise existing assessment methods for teaching the teachers courses in EBM by a systematic review. Methods We searched PubMed, BioMed, EmBase, Cochrane and Eric databases without language restrictions and included articles that assessed its participants. Study selection and data extraction were conducted independently by two reviewers. Results Of 1230 potentially relevant studies, five papers met the selection criteria. There were no specific assessment tools for evaluating effectiveness of EBM TTT courses. Some of the material available might be useful in initiating the development of such an assessment tool. Conclusion There is a need for the development of educationally sound assessment tools for teaching the teachers courses in EBM, without which it would be impossible to ascertain if such courses have the desired effect