1 research outputs found
Copper Cocatalyst Modulated Radical Generation for Selective Heterogeneous Photosynthesis of α‑Haloketones
The α-haloketones are important precursors for
synthetic
chemistry and pharmaceutical applications; however, their production
relies heavily on traditional synthetic methods via halogenation of
ketones that are toxic and environmentally risky. Here, we report
a heterogeneous photosynthetic strategy of α-haloketone production
from aromatic olefins using copper-modified graphitic carbon nitride
(Cu–C3N4) under mild reaction conditions.
By employing NiX2 (X = Cl, Br) as the halogen source, a
series of α-haloketones can be synthesized using atmospheric
air as the oxidant under visible-light irradiation. In comparison
with pristine carbon nitride, the addition of Cu as a cocatalyst provides
a moderate generation rate of halogen radicals and selective reduction
of molecular oxygen into •OOH radicals, thus leading
to a high selectivity to α-haloketones. The Cu–C3N4 also exhibits high stability and versatility,
rendering it a promising candidate for solar-driven synthetic applications