Outflow and hot dust emission in high redshift quasars

Correlations of hot dust emission with outflow properties are investigated, based on a large z~2 non-broad absorption lines quasar sample built from the Wide-field Infrared Survey and the Sloan Digital Sky Survey data releases. We use the near infrared slope and the infrared to UV luminosity ratio to indicate the hot dust emission relative to the emission from the accretion disk. In our luminous quasars, these hot dust emission indicators are almost independent of the fundamental parameters, such as luminosity, Eddington ratio and black hole mass, but moderately dependent on the blueshift and asymmetry index (BAI) and full width at half-maximum (FWHM) of CIV lines. Interestingly, the latter two correlations dramatically strengthen with increasing Eddington ratio. We suggest that, in high Eddington ratio quasars, CIV regions are dominated by outflows so the BAI and FWHM(CIV) can reliably reflect the general properties and velocity of outflows, respectively. While in low Eddington ratio quasars, CIV lines are primarily emitted by virialized gas so the BAI and FWHM(CIV) become less sensitive to outflows. Therefore, the correlations for the highest Eddington ratio quasars are more likely to represent the true dependence of hot dust emission on outflows and the correlations for the entire sample are significantly diluted by the low Eddington ratio quasars. Our results show that an outflow with a large BAI or velocity can double the hot dust emission on average. We suggest that outflows either contain hot dust in themselves or interact with the dusty interstellar medium or torus.Comment: 14 page, 4 figures, accepted for publication in ApJ

Outflow and hot dust emission in broad absorption line quasars

We have investigated a sample of 2099 broad absorption line (BAL) quasars with z=1.7-2.2 built from the Sloan Digital Sky Survey Data Release Seven and the Wide-field Infrared Survey. This sample is collected from two BAL quasar samples in the literature, and refined by our new algorithm. Correlations of outflow velocity and strength with hot dust indicator (beta_NIR) and other quasar physical parameters, such as Eddington ratio, luminosity and UV continuum slope, are explored in order to figure out which parameters drive outflows. Here beta_NIR is the near-infrared continuum slope, a good indicator of the amount of hot dust emission relative to accretion disk emission. We confirm previous findings that outflow properties moderately or weakly depends on Eddington ratio, UV slope and luminosity. For the first time, we report moderate and significant correlations of outflow strength and velocity with beta_NIR in BAL quasars. It is consistent with the behavior of blueshifted broad emission lines in non-BAL quasars. The statistical analysis and composite spectra study both reveal that outflow strength and velocity are more strongly correlated with beta_NIR than Eddington ratio, luminosity and UV slope. In particular, the composites show that the entire C IV absorption profile shifts blueward and broadens as beta_NIR increases, while Eddington ratio and UV slope only affect the high and low velocity part of outflows, respectively. We discuss several potential processes and suggest that dusty outflow scenario, i.e. dust is intrinsic to outflows and may contribute to the outflow acceleration, is most likely. The BAL quasar catalog is available from the authors upon request.Comment: 16 pages, 10 figures, 2 tables; Accepted for publication in The Astrophysical Journa

Diffraction of digital micromirror device gratings and its effect on properties of tunable fiber lasers

A digital micromirror device (DMD) is a kind of widely used spatial light modulator. We apply DMD as wavelength selector in tunable fiber lasers. Based on the two-dimensional diffraction theory, the diffraction of DMD and its effect on properties of fiber laser parameters are analyzed in detail. The theoretical results show that the diffraction efficiency is strongly dependent upon the angle of incident light and the pixel spacing of DMD. Compared with the other models of DMDs, the 0.55 in. DMD grating is an approximate blazed state in our configuration, which makes most of the diffracted radiation concentrated into one order. It is therefore a better choice to improve the stability and reliability of tunable fiber laser systems

Risk assessment of heavy metals in soils contaminated by smelting waste for the perspective of chemical fraction and spatial distribution

The heavy metals contamination in soil has attracted increasing attention. In this study, the main objective was to determine three heavy metals (Cd, Pb, and Cr) of soils contaminated by smelting waste, and to evaluate pollution risk. The Pb (15.48 mg/kg) and Cd (311.39 mg/kg) mean concentrations exceeded the national standard, while Cr (48.60 mg/kg) concentration did not exceed. The Heavy metal fractions analysis showed that three heavy metals were dominated by FeMn oxides fraction (Fe-Mn). The correlation and cluster analysis indicated that there was significant correlation between Cd and Pb (0.55< r < 0.96), while Cr was not correlation to Cd and Pb. The environmental pollution of heavy metals was assessed by the ratio of secondary phase and primary phase (RSP). The result showed that RSP values of Cd, Pb, and Cr range from 13.05–54.28, 16.11–4.97 and 1.61–52.33, which indicated soil was serious contaminated by them. These results showed that smelting waste discharge led to this smelter soil being seriously contaminated by multiple heavy metals which have a tendency to transport and accumulate into deep soil due to their high fractional transformation

Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Medicinal Chemistry, Copyright © 2022 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jmedchem.2c00204.The perinucleolar compartment (PNC) is a dynamic subnuclear body found at the periphery of the nucleolus. The PNC is enriched with RNA transcripts and RNA-binding proteins, reflecting different states of genome organization. PNC prevalence positively correlates with cancer progression and metastatic capacity, making it a useful marker for metastatic cancer progression. A high-throughput, high-content assay was developed to identify novel small molecules that selectively reduce PNC prevalence in cancer cells. We identified and further optimized a pyrrolopyrimidine series able to reduce PNC prevalence in PC3M cancer cells at submicromolar concentrations without affecting cell viability. Structure–activity relationship exploration of the structural elements necessary for activity resulted in the discovery of several potent compounds. Analysis of in vitro drug-like properties led to the discovery of the bioavailable analogue, metarrestin, which has shown potent antimetastatic activity with improved survival in rodent models and is currently being evaluated in a first-in-human phase 1 clinical trial

Analysis of Springback Behaviour in Micro Flexible Rolling of Crystalline Materials

,is paper presents a constitutive modelling of the polycrystalline thin metal strip under a state of combined loading in microflexible rolling. ,e concept of grained inhomogeneity is incorporated into the classic Chaboche hardening model that accounts for the Bauschinger effect, in order to provide more precise description and analysis of the springback mechanism in the particular forming operation. ,e model is first implemented in the finite element program ABAQUS to numerically predict the stress-strain relationship of 304 stainless steel specimens over a range of average grain sizes. After validation of the developed model by comparison of predicted curves and actual stress-strain data points, it is further applied to predict the thickness directional springback in microflexible rolling of 304 stainless steel strips with initial thickness of 250 μm and reduction changing from 5 to 10%. ,e model predictions show a reasonable agreement with the experimental measurements and have proven to be more accurate than those obtained from the conventional multilinear isotropic hardening model in combination with the Voronoi tessellation technique. In addition, the variation of thickness directional springback along with the scatter effect is compared and analysed in regard to the average grain size utilising both qualitative and quantitative approaches in respect of distinct types of data at different reductions

Analysis of Springback Behaviour in Micro Flexible Rolling of Crystalline Materials

This paper presents a constitutive modelling of the polycrystalline thin metal strip under a state of combined loading in microflexible rolling. The concept of grained inhomogeneity is incorporated into the classic Chaboche hardening model that accounts for the Bauschinger effect, in order to provide more precise description and analysis of the springback mechanism in the particular forming operation. The model is first implemented in the finite element program ABAQUS to numerically predict the stress-strain relationship of 304 stainless steel specimens over a range of average grain sizes. After validation of the developed model by comparison of predicted curves and actual stress-strain data points, it is further applied to predict the thickness directional springback in microflexible rolling of 304 stainless steel strips with initial thickness of 250 µm and reduction changing from 5 to 10%. The model predictions show a reasonable agreement with the experimental measurements and have proven to be more accurate than those obtained from the conventional multilinear isotropic hardening model in combination with the Voronoi tessellation technique. In addition, the variation of thickness directional springback along with the scatter effect is compared and analysed in regard to the average grain size utilising both qualitative and quantitative approaches in respect of distinct types of data at different reductions

Synthesis of chiral mono(N-heterocyclic carbene) palladium and gold complexes with a 1,1'-biphenyl scaffold and their applications in catalysis

Axially chiral mono(NHC)–Pd(II) and mono(NHC)–Au(I) complexes with one side shaped 1,1'-biphenyl backbone have been prepared from chiral 6,6'-dimethoxybiphenyl-2,2'-diamine. The complexes were characterized by X-ray crystal structure diffraction. The Pd(II) complex showed good catalytic activities in the Suzuki–Miyaura and Heck–Mizoroki coupling reactions, and the (S)-Au(I) complexes also showed good catalytic activities in the asymmetric intramolecular hydroamination reaction to give the corresponding product in moderate ee