Preliminary Surface Study of Short Term Dissolution of UK High Level Waste Glass

AbstractA simulated Magnox glass which is Mg- and Al- rich was subjected to aqueous corrosion in static mode with deionised water at 90°C for 7 days and assessed using Cameca and Ion-ToF Secondary Ion Mass Spectrometry (SIMS). Depth profiling and ion imaging were done for both unleached and leached samples to reveal elemental distributions from the glass surface into the bulk. All the elements were distributed evenly for unleached glass. After leaching, depletion of alkali ions i.e. Na and Li was observed indicating the interdiffusion (ion exchange) process of the initial stage of leaching. Enrichment of Mg near the surface layer indicated precipitation of Mg-rich crystals at the near surface region

Early stages of surface alteration of soda-rich-silicate glasses in the museum environment

This paper studied the alteration of three soda-rich-silicate glass types (Cristallo, façon-de-Venise and soda-lime silicate). Replica samples were exposed to different environments simulating museum-like conditions – room temperature and different relative humidities (RH). Results were analysed by SIMS, μ-FTIR, Optical Microscopy and Optical 3D profilometry. Cristallo appears as the most vulnerable, whilst the soda-lime glass appears as the most resistant to the environmental deterioration. The thickness of the altered layer is proportional to the time of exposure and to the RH of the surrounding atmosphere. From the results obtained, the glass composition and the water available and adsorbed to the surface strongly influence the kinetics of the surface alteration

Analysis and imaging of biocidal agrochemicals using ToF-SIMS

ToF-SIMS has been increasingly widely used in recent years to look at biological matrices, in particular for biomedical research, although there is still a lot of development needed to maximise the value of this technique in the life sciences. The main issue for biological matrices is the complexity of the mass spectra and therefore the difficulty to specifically and precisely detect analytes in the biological sample. Here we evaluated the use of ToF-SIMS in the agrochemical field, which remains a largely unexplored area for this technique. We profiled a large number of biocidal active ingredients (herbicides, fungicides, and insecticides); we then selected fludioxonil, a halogenated fungicide, as a model compound for more detailed study, including the effect of co-occurring biomolecules on detection limits. There was a wide range of sensitivity of the ToF-SIMS for the different active ingredient compounds, but fludioxonil was readily detected in real-world samples (wheat seeds coated with a commercial formulation). Fludioxonil did not penetrate the seed to any great depth, but was largely restricted to a layer coating the seed surface. ToF-SIMS has clear potential as a tool for not only detecting biocides in biological samples, but also mapping their distribution

Development and initial testing of the person-centred health care for older adults survey.

Background: Health services are encouraged to adopt a strong person-centered approach to the provision of care and services for older people. The aim of this project was to establish a user-friendly, psychometrically valid, and reliable measure of healthcare staff’s practice, attitudes, and beliefs regarding person-centered healthcare. Methods: Item reduction (factor analysis) of a previously developed “benchmarking person-centred care” survey, followed by psychometric evaluations of the internal consistency reliability and construct validity, was conducted. The initial survey was completed by 1,428 healthcare staff from 17 health services across Victoria, Australia. Results: After removing 17 items from the previously developed “benchmarking person-centred care” survey, the revised 31-item survey (Person-Centred Health Care for Older Adults Survey) attained eight factors that explain 62.7% of the total variance with a Cronbach’s α coefficient of 0.91, indicating excellent internal consistency. Expert consultation confirmed that the revised survey had content validity. Conclusions: The results indicated that the Person-Centred Health Care for Older Adults Survey is a user-friendly, psychometrically valid, and reliable measure of staff perceptions of person-centered healthcare for use in hospital settings

Body size, food habits, reproduction and growth in a population of black whip snakes (Demansia vestigiata) (Serpentes: Elapidae

Abstract. Two species of large black whip snakes (Demansia vestigiata and D. papuensis) are morphologically and ecologically similar and have broadly overlapping distributions. A long history of taxonomic difficulties has meant that most previous taxonomic and ecological studies comprise composite samples of both taxa. Here, we provide ecological data (body sizes, food habits, reproduction and inferred growth rates) collected from captured and road-killed specimens from a tropical population of D. vestigiata at Townsville, north-eastern Queensland, Australia. Males attain larger body sizes and have longer tails than females. All food items were ectotherms (lizards and frogs). Female reproductive cycles were strongly seasonal. Clutch size is significantly positively related to maternal body size. Egg dimensions, clutch mass and neonatal size are reported. Inferred growth rates indicate that sexual maturation is attained at~21 months for females

Life history parameters in acellular extrinsic fiber cementum microstructure

Life-history parameters such as pregnancies, skeletal trauma, and renal disease have previously been identified from hypomineralized growth layers (incremental lines) of acellular extrinsic fiber cementum (AEFC). The precise periodicity of these growth layers remains vaguely approximated, so causal life-history explanations using tooth cementum cannot yet be rigorously calculated or tested. On the other hand, we show how life history parameters in AEFC can be identified by two contrasting elemental detection methods. Based on our results we reject the possibility of accurate estimation of pregnancies and other life history parameters from cementum using scanning electron microscopy alone. Here, we propose a new methodological approach for cementum research, Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS), to measure degree and distribution of mineralization of cementum growth layers. Our results show that Tof-SIMS can significantly increase our knowledge of cementum composition and is therefore a powerful new tool for life history researchers

Structural changes and conductance thresholds in metal-free intrinsic SiOx resistive random access memory

We present an investigation of structural changes in silicon-rich silicon oxide metal-insulator-metal resistive RAM devices. The observed unipolar switching, which is intrinsic to the bulk oxide material and does not involve movement of metal ions, correlates with changes in the structure of the oxide. We use atomic force microscopy, conductive atomic force microscopy, x-ray photoelectron spectroscopy, and secondary ion mass spectroscopy to examine the structural changes occurring as a result of switching. We confirm that protrusions formed at the surface of samples during switching are bubbles, which are likely to be related to the outdiffusion of oxygen. This supports existing models for valence-change based resistive switching in oxides. In addition, we describe parallel linear and nonlinear conduction pathways and suggest that the conductance quantum, G0, is a natural boundary between the high and low resistance states of our devices

Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye.

Accumulation of protein- and lipid-containing deposits external to the retinal pigment epithelium (RPE) is common in the aging eye, and has long been viewed as the hallmark of age-related macular degeneration (AMD). The cause for the accumulation and retention of molecules in the sub-RPE space, however, remains an enigma. Here, we present fluorescence microscopy and X-ray diffraction evidence for the formation of small (0.5-20 μm in diameter), hollow, hydroxyapatite (HAP) spherules in Bruch's membrane in human eyes. These spherules are distinct in form, placement, and staining from the well-known calcification of the elastin layer of the aging Bruch's membrane. Secondary ion mass spectrometry (SIMS) imaging confirmed the presence of calcium phosphate in the spherules and identified cholesterol enrichment in their core. Using HAP-selective fluorescent dyes, we show that all types of sub-RPE deposits in the macula, as well as in the periphery, contain numerous HAP spherules. Immunohistochemical labeling for proteins characteristic of sub-RPE deposits, such as complement factor H, vitronectin, and amyloid beta, revealed that HAP spherules were coated with these proteins. HAP spherules were also found outside the sub-RPE deposits, ready to bind proteins at the RPE/choroid interface. Based on these results, we propose a novel mechanism for the growth, and possibly even the formation, of sub-RPE deposits, namely, that the deposit growth and formation begin with the deposition of insoluble HAP shells around naturally occurring, cholesterol-containing extracellular lipid droplets at the RPE/choroid interface; proteins and lipids then attach to these shells, initiating or supporting the growth of sub-RPE deposits