Obsessive Compulsive Disorder and its Relationship with Some Variables

This study aims at reporting on the prevalence of Obsessive Compulsive Disorder (OCD) and its relation to some variables including gender, college, academic achievement and region among Sultan Qaboos university students. The Arabic adapted version of OCD Scale designed by Ibrahim and Al Fazari (2015) was administered to a sample of 820 students from all university colleges (2014-2015 academic year enrolments). The OCD validity was assessed using face validity, criterion-related validity, and factorial validity. The reliability of the OCD was assessed using Cronbach’s alpha and split-half method. The Cronbach’s alpha coefficient was .86 whereas the split- half method coefficient was .82. This study showed a higher level of obsessive compulsive disorder among university students (48. 53%). It was also found significant relationships between OCD and gender. A higher level of OCD was reported among female than male students. In addition, a significant relationship was found due to the college, academic achievement and region

Pengembangan Literasi Dasar dalam Meningkatkan Minat Membaca dan Menulis pada Anak Usia Dini di Perumahan Indah Permai Desa Petatal

Kuliah Kerja Nyata (KKN) merupakan kegiatan sosial kemasyarakatan bagi mahasiswa yang sedang kuliah. Kegiatan KKN menempatkan mahasiswa dalam kehidupan sosial di masyarakat dan hidup serta berinteraksi dengan masyarakat dalam membantu dan bermanfaat bagi desa dan masyarakat. Kegiatan KKN yang dilakukan adalah mengadakan seminar dengan tema literasi pada anak usia dini. Seminar ini bertujuan untuk mengembangkan literasi dasar anak dalam meningkatkan minat membaca dan menulis. Seminar literasi ini diadakan di Perumahan Indah Permai, Desa Petatal, Kabupaten Baru Bara. Metode penelitian yang digunakan adalah penelitian lapangan. Penelitian ini termasuk dalam penelitian deskriptif kualitatif. Untuk teknik pengumpulan data menggunakan teknik observasi, wawancara dan dokumentasi. Tujuan pengembangan literasi dasar pada anak sejak dini adalah untuk melatih anak membaca dan menulis sejak dini serta menumbuhkan minat membaca dan menulis. Anak-anak di Desa Petatal hanya membaca buku dan menulis saat belajar di sekolah dan jarang membaca buku dan menulis saat di rumah. Hal inilah yang menjadi salah satu penyebab rendahnya minat baca tulis

Cita en París. Nº 6/75

Cita con la belleza, nuevas tendencias en maquillaje -- Entrevista con el pintor Julio Le Parc -- Canta Michel SardouPrograma de entretenimiento dedicado al público femenino ; Disco propiedad de Radio Alcoy cedido para su difusión y conservació

Maternal sepsis in intensive care unit at Omdurman New Hospital-Tertiary Obstetric Facility, Khartoum-Sudan

Introduction: Sever sepsis and septic shock contributes to maternal morbidity and mortality. The etiology of sever sepsis and septic shock during pregnancy and postpartum result from obstetric related or non-obstetric related conditions. Objectives: It aimed to determine rate, characters, morbidity and mortality of septic obstetric cases at Omdurman New Hospital. Methods: It was a descriptive, prospective, analytic, cross-sectional hospital based total coverage study; conducted at Omdurman New Hospital (ONH), Khartoum-Sudan. Results: Sever sepsis and septic shock rate 1.16 (13/1124 = 1.16%) of hospital pregnancy complication admission. Hyperthermia, Tachycardia and hypotension are the main presenting clinical findings and uterine infection is the main focus of sepsis. The mean average Intensive Care Unit (ICU) stay is 6.3-day. Organs dysfunctions are the main morbidity and mortality is reported in five cases. Conclusion: Sever sepsis and septic shock contributes in maternal morbidity and mortality. Safe obstetric care prevents maternal sepsis and improves the outcome. Management of sever sepsis and septic shock remains a challenge in obstetric medicine

Quantitative Proteomics of Synaptosomal Fractions in a Rat Overexpressing Human DISC1 Gene Indicates Profound Synaptic Dysregulation in the Dorsal Striatum.

Disrupted-in-schizophrenia 1 (DISC1) is a key protein involved in behavioral processes and various mental disorders, including schizophrenia and major depression. A transgenic rat overexpressing non-mutant human DISC1, modeling aberrant proteostasis of the DISC1 protein, displays behavioral, biochemical and anatomical deficits consistent with aspects of mental disorders, including changes in the dorsal striatum, an anatomical region critical in the development of behavioral disorders. Herein, dorsal striatum of 10 transgenic DISC1 (tgDISC1) and 10 wild type (WT) littermate control rats was used for synaptosomal preparations and for performing liquid chromatography-tandem mass spectrometry (LC-MS)-based quantitative proteomics, using isobaric labeling (TMT10plex). Functional enrichment analysis was generated from proteins with level changes. The increase in DISC1 expression leads to changes in proteins and synaptic-associated processes including membrane trafficking, ion transport, synaptic organization and neurodevelopment. Canonical pathway analysis assigned proteins with level changes to actin cytoskeleton, Gαq, Rho family GTPase and Rho GDI, axonal guidance, ephrin receptor and dopamine-DARPP32 feedback in cAMP signaling. DISC1-regulated proteins proposed in the current study are also highly associated with neurodevelopmental and mental disorders. Bioinformatics analyses from the current study predicted that the following biological processes may be activated by overexpression of DISC1, i.e., regulation of cell quantities, neuronal and axonal extension and long term potentiation. Our findings demonstrate that the effects of overexpression of non-mutant DISC1 or its misassembly has profound consequences on protein networks essential for behavioral control. These results are also relevant for the interpretation of previous as well as for the design of future studies on DISC1