3 research outputs found
Study of Visual Evoked Potentials in Patients Suffering from Exotropia
Background: The present study aims to investigate the visual evoked potentials in patients with exotropia, a type of ocular deviation in which one or both eyes are deflected outwards.
Material and Methods: Twenty-five patients with exotropia aged 6-8 years participated in this study as a case group, and twenty-five age- and sex-matched controls were selected as control. VEP was recorded using the Pattern Reversal checkerboard technique for all participants. Latency (msec) and amplitude (μV) of VEP, P100 peak were measured in both groups.
Results: The mean amplitude of VEP, P100 peak was 2.92 and 7.84 μV in case and control groups, respectively, showing a statistically significant difference (P = 0.001). The difference in mean latency of the VEP, P100 peak was not statistically significant between the two groups (P = 0.45).
Conclusion: Exotropia is a visual disturbance that affects visual evoked potential P100 peak amplitude, whereas the latency of P100 remains intact
Flash Visual Evoked Potential Recording in Patients with Orbital Fracture
Background:Â This study aims to record and analyze visual evoked potentials in patients with orbital fractures in order to improve understanding and treatment of this condition.
Materials and Methods:Â In order to assess their visual function, visual evoked potentials (VEP) were recorded using flash stimulation. The latency (in milliseconds) and amplitude (in microvolts) of the P100 component of the VEP were measured in the patient group and compared to a control group of 11 individuals matched for age and sex who had a healthy visual system.
Results: TThe study included two groups with an equal number of males and females. There, no statistically significant difference in terms of age and sex between the two groups. The best corrected visual acuity (BCVA) showed a large difference between the two groups, with the patients having only light perception ability while the control group had full vision (10/10). The mean latency for VEP100 peak was 130.36 ± 8 in the case group and 99.63 ± 2.33 in the control group. The mean amplitude was 1.27 ± 0.46 in the case group and 4.27 ± 0.78 in the control group. Both the latency and amplitude of VEP100 peak showed significant differences between the case and control groups (P < 0.001).
Conclusion: Head trauma can result in eye dysfunction, primarily affecting the visual pathway. One way to diagnose this condition is by measuring the latency and amplitude of the VEP p1000 peak
Retinal Screening of Patients Suffering from Bardet – Biedl Syndrome Using Electroretinography
Background: Bardet-Biedl Syndrome (BBS) is a complex genetic disorder that affects various systems in the body, including the visual system. The aim of this study is to investigate the adverse effects of BBS on the retina using Electroretinography (ERG).
Material and Methods: In this case-control study, 10 BBS patients (6 males and 4 females) aged between 12 and 20 years were selected as the case group. Additionally, 10 age- and sex-matched healthy individuals with normal retinal function were included as the control group. ERG recordings were performed to measure the amplitude (µV) and latency (msec) of the ERG b-wave in both groups.
Results: The mean age of the case group was 15.4 ± 3.06 years, and it was 15 ± 2.78 years in the control group. The mean visual acuity in the case group was 0.49 ± 0.14 (LogMAR), significantly different from the control group with a mean visual acuity of 0 ± 0 (LogMAR). The difference in visual acuity was statistically significant between the two groups. Furthermore, the case group showed significantly lower amplitude and higher latency of the ERG b-wave peak compared to the control group (p < 0.001).
Conclusions: Bardet-Biedl Syndrome has adverse effects on the visual system, particularly the retina, resulting in a decrease in amplitude and an increase in the latency of the ERG b-wave. These findings indicate impaired retinal function in BBS patients, highlighting the importance of early detection and management of retinal abnormalities in individuals affected by this rare genetic disorder