A definition of digital media literacy competences required by workers to collaborate in distance work environments

This chapter is structured as follows. First, we lay out the theoretical framework for our work. We introduce the concept of digital media literacy (DML) and discuss how it positions our object of study beyond a technologically-centered approach, encompasses both basic operational skills and full-fledged competences, and allows us to articulate both functional and critical aspects of these competences. We then specify the relationship between DML and the social practices that actualize them. Finally, we define categories of collaborative work that are essential to our observation of distance collaboration practices. Second, we detail the methods of data collection and analysis we used to infer a map of DML competence from the interview and observational data of sixty workers engaged in distance collaboration in ten public and private Belgian organizations. Third, we present an overview of the results of our analyses, followed by a detailed description of the domains of competence we identified in terms of activities collaborators perform, and dimensions these activities include. Fourth, we offer an alternative, complementary look at our data in the form of aggregated quantitative indicators. Finally, our conclusions are presented based on the discussion of the results

Histidine modification and mutagenesis point to the involvement of a large conformational change in the mechanism of action of phage lambda lysozyme

Phage lambda lysozyme is structurally related to other known lysozymes but its mechanism of action is different from the classical lysozyme mechanism, acting as a transglycosidase rather than a hydrolase. As two conformations have been revealed by the crystal structure, we investigated the effect of mutating and modifying a histidine located near to or far from the active site in the respective closed and open conformations. Whereas its asparagine mutation has little or no effect on activity, its N-carbethoxylation inactivates the enzyme. This provide further evidence for the involvement of the closed conformation and for the need of conformational mobility in lambda lysozyme function

Erratum

Communication interculturelle et mode de résolution de confliten entreprise. Le cas de l’arbre à palabres comme mode de résolutionde conflit dans les entreprises ivoiriennes.Jules Evariste Agnini Toa et Carine LassaradeCet article, publié dans les varias du numéro 29 aux pages 197-208, doit être cosigné par Carine Lassarade.Communication interculturelle et mode de résolution de confliten entreprise. Le cas de l’arbre à palabres comme mode de résolutionde conflit dans les entreprises ivoiriennes.Jules Evariste Agnini Toa et Carine LassaradeCet article, publié dans les varias du numéro 29 aux pages 197-208, doit être cosigné par Carine Lassarade