A physical model of the high-frequency seismic signal generated by debris flows

We propose a physical model for the high‐frequency (>1 Hz) spectral distribution of seismic power generated by debris flows. The modeled debris flow is assumed to have four regions where the impact rate and impulses are controlled by different mechanisms: the flow body, a coarser‐grained snout, a snout lip where particles fall from the snout on the bed, and a dilute front composed of saltating particles. We calculate the seismic power produced by this impact model in two end‐member scenarios, a thin‐flow and thick‐flow limit, which assume that the ratio of grain sizes to flow thicknesses are either near unity or much less than unity. The thin‐flow limit is more appropriate for boulder‐rich flows that are most likely to generate large seismic signals. As a flow passes a seismic station, the rise phase of the seismic amplitude is generated primarily by the snout while the decay phase is generated first by the snout and then the main flow body. The lip and saltating front generate a negligible seismic signal. When ground properties are known, seismic power depends most strongly on both particle diameter and average flow speed cubed, and also depends on length and width of the flow. The effective particle diameter for producing seismic power is substantially higher than the median grain size and close to the 73rd percentile for a realistic grain size distribution. We discuss how the model can be used to estimate effective particle diameter and average flow speed from an integrated measure of seismic power

A physical model of the high-frequency seismic signal generated by debris flows

We propose a physical model for the high‐frequency (>1 Hz) spectral distribution of seismic power generated by debris flows. The modeled debris flow is assumed to have four regions where the impact rate and impulses are controlled by different mechanisms: the flow body, a coarser‐grained snout, a snout lip where particles fall from the snout on the bed, and a dilute front composed of saltating particles. We calculate the seismic power produced by this impact model in two end‐member scenarios, a thin‐flow and thick‐flow limit, which assume that the ratio of grain sizes to flow thicknesses are either near unity or much less than unity. The thin‐flow limit is more appropriate for boulder‐rich flows that are most likely to generate large seismic signals. As a flow passes a seismic station, the rise phase of the seismic amplitude is generated primarily by the snout while the decay phase is generated first by the snout and then the main flow body. The lip and saltating front generate a negligible seismic signal. When ground properties are known, seismic power depends most strongly on both particle diameter and average flow speed cubed, and also depends on length and width of the flow. The effective particle diameter for producing seismic power is substantially higher than the median grain size and close to the 73rd percentile for a realistic grain size distribution. We discuss how the model can be used to estimate effective particle diameter and average flow speed from an integrated measure of seismic power

Toward an improved wall treatment for multiple-correction k-exact schemes

Improved wall boundary treatments are investigated for a family of high-order Godunovtype finite volume schemes based on k-exact polynomial reconstructions in each cell of the primitive variables, via a successive corrections procedure. We focus more particularly on the 1-exact and 2-exact schemes which offer a good trade-off between accuracy and computational efficiency. In both cases, the reconstruction stencil needs to be extended to the boundaries. Additionally, information about wall curvature has to be taken into account, which is done by using a surface model based on bicubic Bézier patches for the walls. The performance of the proposed models is presented for two compressible cases, namely the inviscid flow past a Gaussian bump and the viscous axisymmetric Couette flow

A study on spline quasi-interpolation based quadrature rules for the isogeometric Galerkin BEM

Two recently introduced quadrature schemes for weakly singular integrals [Calabr\`o et al. J. Comput. Appl. Math. 2018] are investigated in the context of boundary integral equations arising in the isogeometric formulation of Galerkin Boundary Element Method (BEM). In the first scheme, the regular part of the integrand is approximated by a suitable quasi--interpolation spline. In the second scheme the regular part is approximated by a product of two spline functions. The two schemes are tested and compared against other standard and novel methods available in literature to evaluate different types of integrals arising in the Galerkin formulation. Numerical tests reveal that under reasonable assumptions the second scheme convergences with the optimal order in the Galerkin method, when performing $h$-refinement, even with a small amount of quadrature nodes. The quadrature schemes are validated also in numerical examples to solve 2D Laplace problems with Dirichlet boundary conditions

Surgical impact on brain tumor invasion: A physical perspective

It is conventional strategy to treat highly malignant brain tumors initially with cytoreductive surgery followed by adjuvant radio- and chemotherapy. However, in spite of all such efforts, the patients' prognosis remains dismal since residual glioma cells continue to infiltrate adjacent parenchyma and the tumors almost always recur. On the basis of a simple biomechanical conjecture that we have introduced previously, we argue here that by affecting the 'volume-pressure' relationship and minimizing surface tension of the remaining tumor cells, gross total resection may have an inductive effect on the invasiveness of the tumor cells left behind. Potential implications for treatment strategies are discussed

Promising System for Selecting Healthy In Vitro–Fertilized Embryos in Cattle

Conventionally, in vitro–fertilized (IVF) bovine embryos are morphologically evaluated at the time of embryo transfer to select those that are likely to establish a pregnancy. This method is, however, subjective and results in unreliable selection. Here we describe a novel selection system for IVF bovine blastocysts for transfer that traces the development of individual embryos with time-lapse cinematography in our developed microwell culture dish and analyzes embryonic metabolism. The system can noninvasively identify prognostic factors that reflect not only blastocyst qualities detected with histological, cytogenetic, and molecular analysis but also viability after transfer. By assessing a combination of identified prognostic factors—(i) timing of the first cleavage; (ii) number of blastomeres at the end of the first cleavage; (iii) presence or absence of multiple fragments at the end of the first cleavage; (iv) number of blastomeres at the onset of lag-phase, which results in temporary developmental arrest during the fourth or fifth cell cycle; and (v) oxygen consumption at the blastocyst stage—pregnancy success could be accurately predicted (78.9%). The conventional method or individual prognostic factors could not accurately predict pregnancy. No newborn calves showed neonatal overgrowth or death. Our results demonstrate that these five predictors and our system could provide objective and reliable selection of healthy IVF bovine embryos

Environmental demands and the emergence of social structure: Technological dynamism and interorganizational network forms

This study investigates the origins of variation in the structures of global interorganizational networks across industries. We combine empirical analyses of existing interorganizational networks with an agent-based simulation model of network emergence. Our insights are twofold. First, we find that differences in technological dynamism across industries and the concomitant demands for value creation engender variation in firms ’ collaborative behaviors. Specifically, firms in technologically dynamic industries on average pursue more open networks, which foster access to new and diverse resources that help sustain continuous innovation. By contrast, firms in technologically stable industries on average pursue more closed networks, which foster reliable collaboration and help preserve existing resources. Second, we show that because of the observed cross-industry differences in firms ’ collaborative behaviors, the emergent industry-wide networks take on distinct global forms. Technologically stable industries feature clan networks, characterized by low global connectedness and medium-to-strong community structures. Technologically dynamic industries, by contrast, feature community networks, characterized by high connectedness and medium community structures. Convention networks, which feature high global connectedness and weak community structures, wer

Predictors of Intraspinal Pressure and Optimal Cord Perfusion Pressure After Traumatic Spinal Cord Injury.

BACKGROUND/OBJECTIVES: We recently developed techniques to monitor intraspinal pressure (ISP) and spinal cord perfusion pressure (SCPP) from the injury site to compute the optimum SCPP (SCPPopt) in patients with acute traumatic spinal cord injury (TSCI). We hypothesized that ISP and SCPPopt can be predicted using clinical factors instead of ISP monitoring. METHODS: Sixty-four TSCI patients, grades A-C (American spinal injuries association Impairment Scale, AIS), were analyzed. For 24 h after surgery, we monitored ISP and SCPP and computed SCPPopt (SCPP that optimizes pressure reactivity). We studied how well 28 factors correlate with mean ISP or SCPPopt including 7 patient-related, 3 injury-related, 6 management-related, and 12 preoperative MRI-related factors. RESULTS: All patients underwent surgery to restore normal spinal alignment within 72 h of injury. Fifty-one percentage had U-shaped sPRx versus SCPP curves, thus allowing SCPPopt to be computed. Thirteen percentage, all AIS grade A or B, had no U-shaped sPRx versus SCPP curves. Thirty-six percentage (22/64) had U-shaped sPRx versus SCPP curves, but the SCPP did not reach the minimum of the curve, and thus, an exact SCPPopt could not be calculated. In total 5/28 factors were associated with lower ISP: older age, excess alcohol consumption, nonconus medullaris injury, expansion duroplasty, and less intraoperative bleeding. In a multivariate logistic regression model, these 5 factors predicted ISP as normal or high with 73% accuracy. Only 2/28 factors correlated with lower SCPPopt: higher mean ISP and conus medullaris injury. In an ordinal multivariate logistic regression model, these 2 factors predicted SCPPopt as low, medium-low, medium-high, or high with only 42% accuracy. No MRI factors correlated with ISP or SCPPopt. CONCLUSIONS: Elevated ISP can be predicted by clinical factors. Modifiable factors that may lower ISP are: reducing surgical bleeding and performing expansion duroplasty. No factors accurately predict SCPPopt; thus, invasive monitoring remains the only way to estimate SCPPopt